Basic Information
ID: ALA1764757
Type: Binding
Description: Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation counting
Organism: Mus musculus
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA1764757
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 315.85 | 4.52 | 4.52 |
| 285.44 | 3.86 | 3.86 |
| 323.83 | 4.61 | 4.61 |
| 399.93 | 6.27 | 6.27 |
| 435.36 | 6.32 | 6.32 |
| 367.84 | 4.30 | 4.30 |
| 366.85 | 3.70 | 3.70 |
| 394.91 | 4.36 | 4.36 |
| 422.96 | 5.13 | 5.13 |
| 406.92 | 4.50 | 4.50 |
| 420.94 | 4.89 | 4.89 |
| 406.92 | 4.45 | 4.45 |
| 420.94 | 4.84 | 4.84 |
| 436.94 | 4.08 | 4.08 |
| 402.28 | 4.96 | 4.96 |
| 401.30 | 4.36 | 4.36 |
| 338.84 | 4.19 | 4.19 |
| 380.88 | 4.56 | 4.56 |
| 444.93 | 4.65 | 4.65 |
| 448.98 | 5.92 | 5.92 |
| 460.97 | 6.07 | 6.07 |
| 433.90 | 4.85 | 4.85 |
| 373.29 | 4.84 | 4.84 |
| 415.32 | 5.22 | 5.22 |
| 479.37 | 5.30 | 5.30 |
| 401.90 | 5.06 | 5.06 |
| 416.92 | 4.64 | 4.64 |
| 417.90 | 4.77 | 4.77 |
| 461.95 | 5.08 | 5.08 |
| 401.90 | 5.06 | 5.06 |
| 417.90 | 4.77 | 4.77 |
| 436.35 | 5.72 | 5.72 |
| 416.92 | 4.64 | 4.64 |
| 390.87 | 5.26 | 5.26 |
| 418.93 | 5.88 | 5.88 |
| 390.87 | 5.26 | 5.26 |
| 405.95 | 6.33 | 6.33 |
| 418.90 | 5.81 | 5.81 |
| 430.94 | 5.68 | 5.68 |
| 416.91 | 5.37 | 5.37 |
| 419.89 | 5.20 | 5.20 |
| 467.91 | 5.66 | 5.66 |
| 444.93 | 4.16 | 4.16 |
| 409.88 | 2.80 | 2.80 |
| 454.34 | 5.66 | 5.66 |