Assay Report Card

Basic Information

ID: ALA1764758

Type: Functional

Description: Inhibition of 11beta-HSD1 in ICR mouse assessed as conversion of [3H]cortisone to [3H]cortisol at 10 mg/kg, po after 16 hrs by scintillation counting

Organism: Mus musculus

Strain: ICR

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
435.366.326.32
367.844.304.30
366.853.703.70
394.914.364.36
422.965.135.13
420.944.844.84
402.284.964.96
401.304.364.36
338.844.194.19
380.884.564.56
444.934.654.65
448.985.925.92
460.976.076.07
433.904.854.85
373.294.844.84
415.325.225.22
479.375.305.30
401.905.065.06
416.924.644.64
461.955.085.08
401.905.065.06
417.904.774.77
436.355.725.72
418.935.885.88
390.875.265.26
405.956.336.33
418.905.815.81
430.945.685.68
416.915.375.37
419.895.205.20
467.915.665.66
409.882.802.80
454.345.665.66