Basic Information
ID: ALA1768753
Type: Binding
Description: Inhibition of PI3Kalpha in human PC3 cells expressing Akt1 S473D mutant assessed as phosphorylation of Akt Thr308 by immunoblotting
Organism: Homo sapiens
Cell type: PC-3
Activity Charts
Bioactivity
Activity Types for Assay ALA1768753
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 607.64 | 6.83 | 6.83 |
| 485.44 | 6.91 | 6.91 |
| 432.41 | 5.20 | 5.20 |
| 424.36 | 5.09 | 5.09 |
| 438.38 | 5.10 | 5.10 |
| 450.40 | 5.34 | 5.34 |
| 451.38 | 4.74 | 4.74 |
| 474.42 | 6.24 | 6.24 |
| 474.42 | 6.24 | 6.24 |
| 431.47 | 6.20 | 6.20 |
| 370.39 | 4.38 | 4.38 |
| 384.41 | 4.39 | 4.39 |
| 411.44 | 5.06 | 5.06 |
| 460.39 | 5.63 | 5.63 |
| 397.41 | 4.03 | 4.03 |
| 420.45 | 5.53 | 5.53 |
| 451.89 | 6.55 | 6.55 |
| 404.83 | 4.73 | 4.73 |
| 440.87 | 5.87 | 5.87 |
| 417.83 | 4.37 | 4.37 |
| 416.84 | 4.98 | 4.98 |
| 435.43 | 6.03 | 6.03 |
| 388.38 | 4.22 | 4.22 |
| 485.44 | 6.91 | 6.91 |
| 438.38 | 5.10 | 5.10 |
| 424.36 | 5.09 | 5.09 |