Basic Information
ID: ALA1771831
Type: Binding
Description: Inhibition of human recombinant BACE-1 expressed in HEK293 cells assessed as inhibition of amyloid precursor protein cleavage into amyloid beta after 60 mins using Rh-EVNLDAEFK-Quencher as a substrate by FRET assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1771831
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 302.24 | 1.99 | 1.99 |
| 420.46 | 5.27 | 5.27 |
| 422.48 | 5.30 | 5.30 |
| 286.24 | 2.28 | 2.28 |
| 438.48 | 4.46 | 4.46 |
| 420.46 | 5.27 | 5.27 |
| 418.45 | 5.46 | 5.46 |
| 436.46 | 4.13 | 4.13 |
| 452.46 | 3.21 | 3.21 |