Basic Information
ID: ALA1771833
Type: Functional
Description: Antagonist activity at human EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium concentration after 1 hr by FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Prostanoid EP3 receptor(ALA3710)
Document: ALA1770146
Antagonist activity at human EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium concentration after 1 hr by FLIPR assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1771833
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 334.33 | 2.68 | 2.68 |
| 362.39 | 3.31 | 3.31 |
| 360.37 | 3.07 | 3.07 |
| 388.42 | 3.85 | 3.85 |
| 402.45 | 4.24 | 4.24 |
| 396.40 | 3.71 | 3.71 |
| 410.43 | 3.90 | 3.90 |
| 388.30 | 3.22 | 3.22 |
| 404.42 | 3.08 | 3.08 |
| 348.36 | 3.02 | 3.02 |
| 376.41 | 3.80 | 3.80 |
| 333.35 | 2.25 | 2.25 |
| 319.36 | 2.72 | 2.72 |
| 320.35 | 3.15 | 3.15 |
| 347.37 | 4.00 | 4.00 |
| 333.34 | 3.69 | 3.69 |
| 346.39 | 4.02 | 4.02 |
| 362.39 | 3.31 | 3.31 |
| 348.36 | 2.69 | 2.69 |
| 396.83 | 3.97 | 3.97 |
| 441.28 | 4.08 | 4.08 |
| 376.41 | 3.62 | 3.62 |
| 438.48 | 4.98 | 4.98 |
| 430.38 | 4.33 | 4.33 |
| 362.39 | 3.31 | 3.31 |
| 362.39 | 3.31 | 3.31 |