Basic Information
ID: ALA1772078
Type: Binding
Description: Inhibition of human ICMT at 10 uM incubated with N-Acetyl-S-farnesyl-L-cysteine substrate for 5 mins followed by addition of [14C]-SAM measured after 30 mins by liquid scintillation counting
Format: BAO_0000357
Organism: Homo sapiens
Target: Isoprenylcysteine carboxyl methyltransferase(ALA4699)
Document: ALA1770082
Inhibition of human ICMT at 10 uM incubated with N-Acetyl-S-farnesyl-L-cysteine substrate for 5 mins followed by addition of [14C]-SAM measured after 30 mins by liquid scintillation counting: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1772078
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 535.82 | 7.11 | 7.11 |
| 541.78 | 7.24 | 7.24 |
| 479.71 | 5.88 | 5.88 |
| 491.72 | 6.21 | 6.21 |
| 550.61 | 6.39 | 6.39 |
| 501.80 | 6.87 | 6.87 |
| 522.73 | 5.53 | 5.53 |
| 591.92 | 8.94 | 8.94 |
| 479.71 | 5.71 | 5.71 |
| 507.76 | 6.52 | 6.52 |
| 495.71 | 5.58 | 5.58 |
| 540.70 | 5.49 | 5.49 |
| 533.68 | 6.59 | 6.59 |
| 544.58 | 6.33 | 6.33 |
| 507.76 | 6.69 | 6.69 |
| 518.12 | 6.36 | 6.36 |
| 555.63 | 6.27 | 6.27 |
| 465.68 | 5.57 | 5.57 |
| 516.73 | 6.12 | 6.12 |
| 501.66 | 5.85 | 5.85 |
| 521.79 | 6.87 | 6.87 |
| 500.13 | 6.22 | 6.22 |
| 515.74 | 6.72 | 6.72 |
| 510.68 | 5.48 | 5.48 |
| 558.81 | 6.79 | 6.79 |
| 507.72 | 5.77 | 5.77 |
| 525.73 | 5.59 | 5.59 |
| 539.80 | 5.91 | 5.91 |
| 510.68 | 5.48 | 5.48 |
| 525.73 | 5.59 | 5.59 |
| 510.68 | 5.48 | 5.48 |
| 483.67 | 5.71 | 5.71 |
| 471.71 | 5.63 | 5.63 |
| 397.56 | 3.84 | 3.84 |
| 442.56 | 3.75 | 3.75 |
| 415.55 | 3.98 | 3.98 |
| 390.48 | 2.64 | 2.64 |
| 460.62 | 4.59 | 4.59 |
| 557.78 | 7.36 | 7.36 |