Basic Information
ID: ALA1772079
Type: Binding
Description: Inhibition of human ICMT incubated with N-Acetyl-S-farnesyl-L-cysteine substrate for 5 mins followed by addition of [14C]-SAM measured after 30 mins by liquid scintillation counting
Format: BAO_0000357
Organism: Homo sapiens
Target: Isoprenylcysteine carboxyl methyltransferase(ALA4699)
Document: ALA1770082
Inhibition of human ICMT incubated with N-Acetyl-S-farnesyl-L-cysteine substrate for 5 mins followed by addition of [14C]-SAM measured after 30 mins by liquid scintillation counting: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1772079
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 465.68 | 5.57 | 5.57 |
| 558.81 | 6.79 | 6.79 |
| 510.68 | 5.48 | 5.48 |
| 483.67 | 5.71 | 5.71 |
| 471.71 | 5.63 | 5.63 |
| 557.78 | 7.36 | 7.36 |