Basic Information
ID: ALA1772131
Type: Binding
Description: Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-evoked current by manual patch-clamp electrophysiology assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1772131
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 215.26 | 2.54 | 2.54 |
| 170.21 | 2.33 | 2.33 |
| 225.25 | 3.27 | 3.27 |
| 212.09 | 2.09 | 2.09 |
| 171.20 | 1.73 | 1.73 |
| 164.23 | 1.75 | 1.75 |
| 163.24 | 2.36 | 2.36 |
| 159.19 | 1.66 | 1.66 |
| 173.22 | 1.54 | 1.54 |
| 170.21 | 2.33 | 2.33 |
| 238.29 | 2.06 | 2.06 |
| 270.33 | 3.73 | 3.73 |
| 261.33 | 3.32 | 3.32 |
| 353.26 | 4.87 | 4.87 |
| 371.28 | 4.50 | 4.50 |
| 278.18 | 4.31 | 4.31 |
| 307.44 | 3.77 | 3.77 |
| 277.29 | 4.02 | 4.02 |
| 436.48 | 6.42 | 6.42 |
| 251.33 | 2.36 | 2.36 |
| 307.44 | 2.75 | 2.75 |
| 375.44 | 3.77 | 3.77 |
| 266.34 | 3.26 | 3.26 |
| 345.45 | 3.61 | 3.61 |
| 367.88 | 4.40 | 4.40 |