Assay Report Card

Basic Information

ID: ALA1775252

Type: Functional

Description: In vivo antihistaminic activity at histamine H1 receptor in ddY mouse assessed as inhibition of histamine-induced skin vascular permeability at 3 mg/kg, po administered 1 hr before histamine challenge by Evan's blue staining

Organism: Mus musculus

Strain: ddY

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
521.642.532.53
519.602.422.42
517.632.622.62
559.713.293.29
516.602.252.25
530.632.642.64