Basic Information
ID: ALA1775840
Type: Binding
Description: Inhibition of Mycobacterium tuberculosis N-terminal His6-tagged PTPB preincubated with compound for 30 mins before pNPP substrate addition by microplate spectrophotometer analysis
Format: BAO_0000357
Organism: Mycobacterium tuberculosis
Target: Phosphotyrosine-protein phosphatase PTPB(ALA4540)
Document: ALA1773067
Inhibition of Mycobacterium tuberculosis N-terminal His6-tagged PTPB preincubated with compound for 30 mins before pNPP substrate addition by microplate spectrophotometer analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1775840
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 380.47 | 4.55 | 4.55 |
| 418.47 | 4.83 | 4.83 |
| 424.87 | 4.72 | 4.72 |
| 520.61 | 6.39 | 6.39 |
| 492.55 | 5.61 | 5.61 |
| 482.61 | 3.03 | 3.03 |
| 481.60 | 2.97 | 2.97 |
| 533.67 | 4.10 | 4.10 |
| 510.64 | 3.58 | 3.58 |
| 506.63 | 3.16 | 3.16 |