Assay Report Card

Basic Information

ID: ALA1777174

Type: Functional

Description: In vivo inhibition of mTORC1 in po dosed NCR nude mouse xenografted with human NCI-PC3 cells assessed as reduction in phosphorylated S6RP level after 10 hrs

Organism: Mus musculus

Strain: NCR

Cell type: NCI-PC3

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
411.513.283.28
441.532.642.64