Basic Information
ID: ALA1777177
Type: Functional
Description: In vivo inhibition of mTORC2 in NCR nude mouse xenografted with human NCI-PC3 cells assessed as reduction in phosphorylated Akt level at 25 to 100 mg/kg, po administered as single dose relative to control
Organism: Mus musculus
Strain: NCR
Cell type: NCI-PC3
Activity Charts
Bioactivity
Activity Types for Assay ALA1777177
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 411.51 | 3.28 | 3.28 |
| 441.53 | 2.64 | 2.64 |