Antagonist activity at human XIAP linker BIR2-BIR3 domain assessed as restoration of caspase 9 activity at 1.5 uM preincubated for 15 mins using Z-LEH...

Basic Information

ID: ALA1777204

Type: Functional

Description: Antagonist activity at human XIAP linker BIR2-BIR3 domain assessed as restoration of caspase 9 activity at 1.5 uM preincubated for 15 mins using Z-LEHD substrate by caspase-Glo 9 assay

Format: BAO_0000019

Organism: Homo sapiens

Target:  Inhibitor of apoptosis protein 3(ALA4198)

Document:  ALA1772970

Antagonist activity at human XIAP linker BIR2-BIR3 domain assessed as restoration of caspase 9 activity at 1.5 uM preincubated for 15 mins using Z-LEHD substrate by caspase-Glo 9 assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
476.622.922.92
1121.45
1037.28
1065.34
1093.39
1177.55
1233.66
1101.46
1093.34
1264.59