Basic Information
ID: ALA1777341
Type: Binding
Description: Inhibition of human microsomal PGES1 in cell-free system assessed as inhibition of conversion of PGH2 to PGE2 by HPLC assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1777341
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 387.59 | 6.49 | 6.49 |
| 465.70 | 7.94 | 7.94 |
| 502.05 | 7.66 | 7.66 |
| 482.06 | 7.74 | 7.74 |
| 508.06 | 8.64 | 8.64 |
| 526.05 | 8.78 | 8.78 |
| 560.50 | 9.43 | 9.43 |
| 540.08 | 9.09 | 9.09 |
| 464.96 | 6.64 | 6.64 |
| 611.95 | 9.23 | 9.23 |
| 441.57 | 7.00 | 7.00 |
| 574.77 | 9.49 | 9.49 |
| 616.59 | 9.48 | 9.48 |
| 481.02 | 6.93 | 6.93 |
| 512.36 | 6.88 | 6.88 |
| 572.57 | 4.05 | 4.05 |
| 565.41 | 8.49 | 8.49 |
| 449.96 | 6.56 | 6.56 |
| 575.96 | 7.27 | 7.27 |
| 407.97 | 6.01 | 6.01 |
| 470.04 | 6.92 | 6.92 |
| 489.35 | 4.51 | 4.51 |
| 641.00 | 7.84 | 7.84 |
| 442.61 | 6.19 | 6.19 |
| 499.42 | 7.04 | 7.04 |
| 535.33 | 7.00 | 7.00 |
| 403.54 | 5.25 | 5.25 |