Basic Information
ID: ALA1777342
Type: Binding
Description: Inhibition of human microsomal PGES1 in cell-free system assessed as inhibition of conversion of PGH2 to PGE2 at 10 uM by HPLC assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1777342
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 472.09 | 8.01 | 8.01 |
| 512.36 | 6.88 | 6.88 |
| 572.57 | 4.05 | 4.05 |
| 565.41 | 8.49 | 8.49 |
| 489.35 | 4.51 | 4.51 |
| 641.00 | 7.84 | 7.84 |
| 442.61 | 6.19 | 6.19 |
| 499.42 | 7.04 | 7.04 |
| 535.33 | 7.00 | 7.00 |
| 403.54 | 5.25 | 5.25 |