Basic Information
ID: ALA1780986
Type: Functional
Description: Antagonist activity at human recombinant P2X7 receptor expressed in HEK293 cells assessed as inhibition of benzoylbenzoic ATP-induced calcium production by FLIPR assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1780986
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 319.20 | 4.00 | 4.00 |
| 306.16 | 3.09 | 3.09 |
| 318.21 | 4.61 | 4.61 |
| 333.22 | 4.49 | 4.49 |
| 398.28 | 2.98 | 2.98 |
| 350.21 | 3.59 | 3.59 |
| 350.21 | 3.59 | 3.59 |
| 320.18 | 3.58 | 3.58 |
| 334.21 | 3.89 | 3.89 |
| 320.18 | 4.02 | 4.02 |
| 338.17 | 3.72 | 3.72 |
| 338.17 | 3.72 | 3.72 |
| 338.17 | 3.72 | 3.72 |
| 345.19 | 3.45 | 3.45 |
| 366.28 | 4.30 | 4.30 |
| 363.25 | 3.65 | 3.65 |
| 435.36 | 4.30 | 4.30 |
| 405.29 | 3.42 | 3.42 |
| 386.19 | 4.18 | 4.18 |
| 364.24 | 3.98 | 3.98 |
| 378.26 | 4.37 | 4.37 |
| 354.63 | 4.23 | 4.23 |
| 354.63 | 4.23 | 4.23 |
| 354.63 | 4.23 | 4.23 |
| 388.18 | 4.60 | 4.60 |
| 388.18 | 4.60 | 4.60 |
| 388.18 | 4.60 | 4.60 |
| 404.18 | 4.48 | 4.48 |
| 404.18 | 4.48 | 4.48 |
| 404.18 | 4.48 | 4.48 |
| 380.24 | 3.60 | 3.60 |
| 364.19 | 3.31 | 3.31 |
| 362.22 | 3.52 | 3.52 |
| 348.24 | 4.20 | 4.20 |
| 356.16 | 3.86 | 3.86 |
| 356.16 | 3.86 | 3.86 |
| 372.62 | 4.37 | 4.37 |
| 390.61 | 4.51 | 4.51 |
| 346.22 | 4.07 | 4.07 |
| 346.22 | 4.07 | 4.07 |
| 348.19 | 3.51 | 3.51 |
| 348.24 | 4.32 | 4.32 |
| 334.21 | 4.14 | 4.14 |
| 334.21 | 4.14 | 4.14 |
| 334.21 | 3.61 | 3.61 |