Basic Information
ID: ALA1781817
Type: Binding
Description: Inhibition of recombinant squalene synthase assessed as conversion of trans,trans-[1-3H]farnesyl pyrophosphate to [3H]squalene after 10 mins by liquid scintillation counting
Format: BAO_0000357
Target: Squalene synthetase(ALA3338)
Document: ALA1777787
Inhibition of recombinant squalene synthase assessed as conversion of trans,trans-[1-3H]farnesyl pyrophosphate to [3H]squalene after 10 mins by liquid scintillation counting: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1781817
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 603.11 | 4.30 | 4.30 |
| 645.15 | 4.87 | 4.87 |
| 457.91 | 5.77 | 5.77 |
| 457.91 | 5.77 | 5.77 |
| 457.91 | 5.77 | 5.77 |
| 527.02 | 5.28 | 5.28 |
| 583.08 | 6.40 | 6.40 |
| 569.05 | 6.01 | 6.01 |
| 477.94 | 3.67 | 3.67 |