Basic Information
ID: ALA1785541
Type: Binding
Description: Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as substrate after 10 to 15 mins by DCIP dye-based assay
Format: BAO_0000019
Organism: Plasmodium falciparum
Target: Dihydroorotate dehydrogenase(ALA3486)
Document: ALA1781999
Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as substrate after 10 to 15 mins by DCIP dye-based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1785541
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 265.32 | 2.67 | 2.67 |
| 268.32 | 2.24 | 2.24 |
| 267.34 | 3.30 | 3.30 |
| 239.28 | 2.04 | 2.04 |
| 253.31 | 2.74 | 2.74 |
| 267.34 | 3.13 | 3.13 |
| 281.36 | 3.52 | 3.52 |
| 295.39 | 3.91 | 3.91 |
| 309.42 | 4.30 | 4.30 |
| 323.44 | 4.69 | 4.69 |
| 337.47 | 5.08 | 5.08 |
| 281.36 | 3.47 | 3.47 |
| 265.32 | 3.05 | 3.05 |
| 251.29 | 2.82 | 2.82 |
| 249.28 | 2.16 | 2.16 |
| 307.28 | 3.28 | 3.28 |
| 325.32 | 3.79 | 3.79 |
| 351.30 | 4.83 | 4.83 |
| 331.38 | 3.76 | 3.76 |
| 294.36 | 2.78 | 2.78 |
| 310.36 | 2.01 | 2.01 |
| 296.38 | 3.39 | 3.39 |
| 297.36 | 3.35 | 3.35 |
| 292.35 | 2.98 | 2.98 |
| 299.35 | 3.61 | 3.61 |
| 277.69 | 2.97 | 2.97 |
| 361.25 | 4.21 | 4.21 |
| 329.23 | 3.47 | 3.47 |
| 279.35 | 3.06 | 3.06 |
| 269.26 | 1.91 | 1.91 |
| 281.34 | 3.39 | 3.39 |
| 333.28 | 3.07 | 3.07 |
| 189.22 | 1.01 | 1.01 |
| 203.25 | 1.40 | 1.40 |
| 217.28 | 1.79 | 1.79 |
| 231.30 | 2.18 | 2.18 |
| 245.33 | 2.57 | 2.57 |
| 259.36 | 2.96 | 2.96 |
| 315.47 | 4.52 | 4.52 |
| 265.32 | 2.01 | 2.01 |
| 283.31 | 2.15 | 2.15 |
| 344.22 | 2.77 | 2.77 |
| 325.37 | 2.03 | 2.03 |
| 279.35 | 2.40 | 2.40 |
| 297.34 | 2.54 | 2.54 |
| 313.79 | 3.06 | 3.06 |
| 241.25 | 1.84 | 1.84 |
| 257.27 | 2.18 | 2.18 |
| 307.28 | 3.06 | 3.06 |
| 253.31 | 2.09 | 2.09 |
| 267.34 | 2.48 | 2.48 |
| 247.35 | 2.82 | 2.82 |
| 307.28 | 3.45 | 3.45 |
| 347.22 | 3.91 | 3.91 |
| 313.67 | 3.54 | 3.54 |
| 295.39 | 3.86 | 3.86 |
| 337.31 | 3.64 | 3.64 |
| 281.36 | 3.44 | 3.44 |
| 283.31 | 2.80 | 2.80 |