Basic Information
ID: ALA1787315
Type: Functional
Description: Inhibition of cholesterol synthesis in rat hepatocytes assessed as reduction of [14C]-cholesterol level using [14C]-acetic acid preincubated for 4 hrs before addition of [14C]-acetic acid by liquid scintillation counting
Organism: Rattus norvegicus
Cell type: Hepatocyte
Activity Charts
Bioactivity
Activity Types for Assay ALA1787315
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 511.59 | 3.89 | 3.89 |
| 481.55 | 2.40 | 2.40 |
| 535.52 | 3.61 | 3.61 |
| 519.55 | 3.72 | 3.72 |
| 517.53 | 3.47 | 3.47 |
| 531.56 | 3.78 | 3.78 |
| 531.56 | 3.78 | 3.78 |
| 531.56 | 3.78 | 3.78 |
| 547.56 | 3.48 | 3.48 |
| 547.56 | 3.48 | 3.48 |
| 547.56 | 3.48 | 3.48 |
| 535.52 | 3.61 | 3.61 |
| 535.52 | 3.61 | 3.61 |
| 553.51 | 3.75 | 3.75 |
| 553.51 | 3.75 | 3.75 |
| 549.55 | 3.92 | 3.92 |
| 565.55 | 3.62 | 3.62 |
| 560.56 | 2.57 | 2.57 |
| 624.67 | 2.72 | 2.72 |