Basic Information
ID: ALA1787593
Type: Binding
Description: Inhibition of calf thymus topoisomerase 1-mediated relaxation of supercoiled pBR322 assessed as formation of nicked DNA at 1 to 50 uM after 15 mins using ethidium bromide staining by UV transilluminator
Format: BAO_0000357
Organism: Bos taurus
Target: Topoisomerase I(ALA6023)
Document: ALA1781993
Inhibition of calf thymus topoisomerase 1-mediated relaxation of supercoiled pBR322 assessed as formation of nicked DNA at 1 to 50 uM after 15 mins using ethidium bromide staining by UV transilluminator: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1787593
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 488.54 | 3.85 | 3.85 |
| 486.48 | 3.30 | 3.30 |