Basic Information
ID: ALA1787627
Type: ADME
Description: Intrinsic clearance in human liver microsomes at 1 uM after 25 mins by LC/MS/MS analysis in presence of NADPH
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA1787627
CL
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 405.50 | 4.65 | 4.65 |
| 311.43 | 3.77 | 3.77 |
| 286.38 | 2.55 | 2.55 |
| 306.37 | 3.02 | 3.02 |
| 334.42 | 3.64 | 3.64 |
| 334.42 | 3.64 | 3.64 |
| 320.40 | 3.33 | 3.33 |
| 320.40 | 3.33 | 3.33 |
| 334.42 | 3.64 | 3.64 |
| 334.42 | 3.64 | 3.64 |
| 364.41 | 2.79 | 2.79 |
| 392.46 | 3.42 | 3.42 |
| 380.45 | 3.43 | 3.43 |
| 366.42 | 3.04 | 3.04 |
| 378.43 | 3.18 | 3.18 |
| 352.39 | 2.65 | 2.65 |
| 366.42 | 3.03 | 3.03 |
| 420.39 | 3.58 | 3.58 |
| 382.42 | 2.01 | 2.01 |
| 338.37 | 2.26 | 2.26 |
| 380.45 | 3.42 | 3.42 |
| 392.46 | 3.57 | 3.57 |
| 403.48 | 4.26 | 4.26 |
| 403.48 | 4.40 | 4.40 |
| 363.42 | 3.48 | 3.48 |
| 349.39 | 3.09 | 3.09 |
| 389.46 | 4.01 | 4.01 |
| 375.43 | 3.62 | 3.62 |
| 382.40 | 2.93 | 2.93 |
| 384.41 | 3.18 | 3.18 |
| 396.42 | 3.32 | 3.32 |
| 370.38 | 2.79 | 2.79 |
| 384.41 | 3.17 | 3.17 |
| 407.45 | 4.15 | 4.15 |
| 393.42 | 3.76 | 3.76 |
| 381.41 | 3.62 | 3.62 |
| 368.40 | 1.83 | 1.83 |
| 337.38 | 2.42 | 2.42 |
| 350.42 | 3.34 | 3.34 |
| 354.39 | 3.17 | 3.17 |
| 384.41 | 3.18 | 3.18 |
| 383.38 | 2.32 | 2.32 |
| 384.37 | 1.72 | 1.72 |
| 349.39 | 2.48 | 2.48 |
| 360.42 | 3.40 | 3.40 |