Basic Information
ID: ALA1787780
Type: Binding
Description: Allosteric modulation of human GABAA alpha3beta3gamma2 receptor expressed in Xenopus laevis oocytes assessed as effect on GABA-induced chloride current at holding potential of -60mV by two-electrode voltage-clamp electrophysiology assay relative to 1 uM Diazepam
Organism: Homo sapiens
Cell type: Oocyte
Activity Charts
Bioactivity
Activity Types for Assay ALA1787780
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 405.50 | 4.65 | 4.65 |
| 286.38 | 2.55 | 2.55 |
| 320.40 | 3.33 | 3.33 |
| 334.42 | 3.64 | 3.64 |
| 334.42 | 3.64 | 3.64 |
| 366.42 | 3.04 | 3.04 |
| 389.46 | 4.01 | 4.01 |
| 375.43 | 3.62 | 3.62 |
| 382.40 | 2.93 | 2.93 |
| 384.41 | 3.18 | 3.18 |
| 393.42 | 3.76 | 3.76 |
| 368.40 | 1.83 | 1.83 |
| 337.38 | 2.42 | 2.42 |
| 350.42 | 3.34 | 3.34 |
| 354.39 | 3.17 | 3.17 |
| 384.41 | 3.18 | 3.18 |
| 383.38 | 2.32 | 2.32 |
| 384.37 | 1.72 | 1.72 |
| 349.39 | 2.48 | 2.48 |
| 360.42 | 3.40 | 3.40 |