Basic Information
ID: ALA1788054
Type: Binding
Description: Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counter
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA1788054
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 408.88 | 1.84 | 1.84 |
| 467.93 | 2.17 | 2.17 |
| 467.93 | 2.17 | 2.17 |
| 484.00 | 2.64 | 2.64 |
| 484.00 | 2.64 | 2.64 |
| 477.97 | 2.58 | 2.58 |
| 495.96 | 2.72 | 2.72 |
| 481.95 | 2.56 | 2.56 |
| 481.95 | 2.56 | 2.56 |
| 498.02 | 3.03 | 3.03 |
| 498.02 | 3.03 | 3.03 |
| 491.99 | 2.97 | 2.97 |
| 509.98 | 3.11 | 3.11 |
| 493.97 | 2.73 | 2.73 |
| 493.97 | 2.73 | 2.73 |
| 510.03 | 3.20 | 3.20 |
| 510.03 | 3.20 | 3.20 |
| 504.00 | 3.13 | 3.13 |
| 471.96 | 2.77 | 2.77 |
| 521.99 | 3.27 | 3.27 |
| 453.90 | 1.87 | 1.87 |
| 495.98 | 2.95 | 2.95 |
| 491.95 | 2.17 | 2.17 |
| 507.99 | 3.12 | 3.12 |
| 497.95 | 1.53 | 1.53 |
| 511.98 | 2.19 | 2.19 |
| 549.01 | 1.83 | 1.83 |
| 639.05 | 2.10 | 2.10 |
| 467.93 | 1.65 | 1.65 |
| 467.93 | 1.65 | 1.65 |
| 484.00 | 2.12 | 2.12 |
| 484.00 | 2.12 | 2.12 |
| 507.99 | 2.86 | 2.86 |
| 507.99 | 2.86 | 2.86 |
| 524.06 | 3.33 | 3.33 |
| 524.06 | 3.33 | 3.33 |
| 455.89 | 2.30 | 2.30 |
| 455.89 | 2.30 | 2.30 |
| 471.96 | 2.77 | 2.77 |
| 465.93 | 2.71 | 2.71 |
| 483.92 | 2.85 | 2.85 |
| 472.35 | 2.82 | 2.82 |
| 472.35 | 2.82 | 2.82 |
| 488.41 | 3.28 | 3.28 |
| 488.41 | 3.28 | 3.28 |