Assay Report Card

Basic Information

ID: ALA1789905

Type: Functional

Description: NOVARTIS: Antimalarial liver stage activity measured as a greater than 50% reduction in Plasmodium yoelii schizont area in HepG2-A16-CD81 cells at 10uM compound concentration, determined by immuno-fluorescence.

Organism: Plasmodium yoelii

Cell type: HepG2-A16-CD81

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
295.422.842.84
289.341.051.05
174.211.101.10
248.722.522.52
399.975.975.97
371.823.103.10
209.641.781.78
344.855.385.38
296.413.393.39
294.403.163.16
389.525.265.26
221.263.613.61
214.271.871.87
289.722.682.68
480.654.944.94
341.465.035.03
248.241.931.93
333.412.572.57
334.303.393.39
268.741.401.40
367.493.733.73
326.352.502.50
277.803.643.64
368.484.884.88
428.535.045.04
355.402.432.43
289.382.052.05
281.351.041.04
527.586.176.17
279.393.753.75
288.313.363.36
258.283.363.36
282.342.392.39
252.282.592.59
340.814.604.60
306.373.943.94
324.423.173.17
244.692.532.53
520.654.644.64
361.535.885.88
366.514.404.40
347.515.495.49
412.385.875.87
459.385.715.71
355.514.114.11
333.484.934.93
422.503.173.17
442.524.044.04
430.554.354.35
446.553.963.96
362.792.522.52
356.433.903.90
245.282.682.68
259.313.243.24
395.265.345.34
339.423.353.35
382.515.275.27
318.423.733.73
434.974.994.99
478.525.655.65
503.624.774.77
270.724.344.34
225.252.692.69
277.803.823.82
323.423.363.36
317.353.643.64
555.592.232.23
393.323.523.52
478.423.873.87
272.313.663.66
323.423.643.64
353.453.653.65
337.453.953.95
357.874.304.30
267.364.264.26
327.435.955.95
434.544.114.11
319.454.594.59
231.261.251.25
448.914.894.89
463.884.794.79
466.415.145.14
254.323.343.34
329.484.784.78
420.563.353.35
406.496.596.59
384.535.895.89
334.473.443.44
425.327.397.39
291.313.043.04
380.403.013.01
338.373.313.31
313.403.713.71
324.814.164.16
454.323.803.80
286.381.471.47
268.243.133.13
332.792.482.48
233.703.063.06
266.303.703.70
293.373.603.60
273.332.442.44
414.315.175.17
237.263.083.08
356.382.722.72
556.105.965.96
252.112.912.91
333.225.605.60
353.476.126.12
361.234.164.16
297.791.271.27
392.252.442.44
267.282.862.86
430.815.475.47
385.442.252.25
352.394.074.07
370.413.633.63
290.253.793.79
495.157.647.64
405.463.553.55
420.494.174.17
426.355.045.04
332.412.352.35
432.555.115.11
445.804.934.93
338.284.624.62
498.942.892.89
347.466.006.00
419.873.983.98
351.243.433.43
298.774.954.95
449.503.943.94
444.604.994.99
364.455.075.07
420.585.815.81
434.543.953.95
328.404.704.70
427.321.751.75
226.323.283.28
419.935.325.32
297.744.454.45
270.383.613.61
333.393.723.72
323.353.093.09
470.214.044.04
426.524.394.39
367.543.563.56
469.704.184.18
272.381.841.84
496.664.374.37
301.773.703.70
373.884.514.51
456.855.935.93
349.263.653.65
405.264.714.71
398.724.154.15
448.785.015.01
384.444.474.47
590.287.267.26
567.364.904.90
372.453.193.19
311.352.512.51
316.792.782.78
476.505.065.06
212.302.632.63
381.303.823.82
281.363.793.79
485.905.065.06
464.495.545.54
448.915.135.13
413.503.833.83
460.585.905.90
362.485.795.79
420.493.683.68
352.442.302.30
414.344.364.36
517.114.944.94
416.404.314.31
311.354.174.17
304.274.034.03
410.306.156.15
473.405.275.27
407.482.812.81
341.445.945.94
350.383.313.31
346.822.792.79
297.744.454.45
445.525.685.68
444.276.036.03
261.414.114.11
480.245.605.60
490.525.355.35
456.514.034.03
377.874.094.09
357.371.261.26
319.363.473.47
475.388.558.55
351.414.024.02
409.554.754.75
636.7110.4510.45
436.543.713.71
421.504.194.19
360.505.015.01
527.214.054.05
407.473.803.80
354.414.464.46
378.334.894.89
483.525.985.98
419.493.853.85
420.603.633.63
464.495.405.40
442.545.075.07
435.955.655.65
330.394.444.44
417.466.776.77
336.393.673.67
307.403.133.13
400.873.783.78
479.555.165.16
492.505.975.97
336.353.683.68
475.388.558.55
536.424.034.03
281.282.922.92
272.443.923.92
354.623.483.48
289.343.203.20
515.584.404.40
411.284.774.77
281.404.444.44
332.364.284.28
321.423.883.88
486.495.805.80
425.334.944.94
429.383.413.41
253.740.870.87
332.364.284.28
402.885.045.04
352.413.933.93
377.484.974.97
636.7110.4510.45
273.733.143.14
403.484.014.01
358.375.165.16
283.760.880.88
238.082.602.60
354.414.614.61
534.965.035.03
354.424.294.29
430.525.225.22
430.525.535.53
365.444.164.16
403.912.982.98
368.444.394.39
405.453.733.73
683.526.886.88
356.863.983.98
440.184.684.68
305.434.284.28
415.453.333.33
362.893.253.25
342.833.683.68
434.502.712.71
379.443.063.06
278.403.383.38
323.854.114.11
263.773.253.25
453.875.135.13
356.434.694.69
322.454.084.08
308.173.793.79
379.463.953.95
385.353.403.40
492.542.102.10
302.383.193.19
267.343.103.10
391.603.853.85
409.303.803.80
416.523.933.93
350.774.194.19
326.144.414.41
332.412.352.35
402.503.543.54
370.493.803.80
432.495.735.73
378.484.534.53
276.344.274.27
519.838.668.66
396.285.845.84
361.535.825.82
429.014.084.08
267.761.181.18
363.334.564.56
315.804.014.01
463.654.124.12
383.534.804.80
312.844.044.04
455.824.064.06
306.774.034.03
382.454.234.23
367.535.175.17
288.353.773.77
332.631.631.63
395.224.304.30
388.482.462.46
480.954.924.92
350.382.912.91
439.564.324.32
472.424.704.70
379.631.481.48
475.225.795.79
440.544.644.64
334.782.922.92
396.325.035.03
470.176.646.64
379.335.105.10
301.781.831.83
426.544.884.88
352.732.052.05
398.454.814.81
295.343.823.82
362.484.054.05
396.282.512.51
384.304.084.08
382.854.594.59
400.483.753.75
360.804.604.60
288.181.531.53
425.995.045.04
448.915.135.13
251.382.872.87
231.301.421.42
482.225.975.97
256.282.722.72
464.573.863.86
270.382.912.91
267.351.781.78
345.381.581.58
363.372.382.38
325.384.344.34
480.495.595.59
326.443.223.22
562.516.946.94
342.832.862.86
308.342.772.77
266.311.741.74
425.534.234.23
541.656.306.30
579.608.168.16
486.704.354.35
325.393.573.57
294.383.893.89
380.885.205.20
364.452.992.99
364.434.214.21
275.352.252.25
398.491.481.48
268.323.003.00
650.577.957.95
581.947.977.97
418.502.262.26
335.342.352.35
270.34-0.07-0.07
595.795.795.79
301.351.811.81
331.803.503.50
321.423.523.52
307.402.332.33
530.035.005.00
371.444.004.00
368.392.312.31
228.182.692.69
344.844.694.69
552.507.247.24
369.791.801.80
442.144.954.95
490.724.904.90
402.953.393.39
335.813.843.84
545.896.856.85
427.514.594.59
261.092.902.90
392.46-0.10-0.10
449.562.562.56
458.585.725.72
320.353.483.48
341.415.365.36
425.585.745.74
407.903.213.21
270.123.523.52
449.482.432.43
473.363.113.11
481.458.048.04
555.436.986.98
391.565.155.15
380.52
613.865.795.79
586.694.264.26
401.332.782.78
465.642.542.54
292.373.803.80
421.912.232.23
544.704.054.05
342.244.424.42
395.872.902.90
393.724.934.93
453.594.404.40
356.473.923.92
600.819.179.17
327.393.473.47
310.384.224.22
512.744.094.09
294.352.392.39
388.435.235.23
249.272.912.91
358.364.394.39
432.533.813.81
404.275.345.34
324.454.654.65
246.311.651.65
330.270.450.45
543.666.196.19
297.795.095.09
384.412.652.65
323.443.093.09
352.461.041.04
491.465.365.36
300.243.863.86
586.755.635.63
449.286.346.34
335.403.993.99
234.282.162.16
477.652.462.46
311.474.744.74
620.892.162.16
306.391.781.78
378.455.175.17
443.575.905.90
365.474.384.38
425.505.205.20
244.391.091.09
362.473.013.01
465.627.407.40
272.320.550.55
342.422.612.61
318.793.653.65
355.445.265.26
488.517.087.08
277.333.463.46
488.574.644.64
343.434.924.92
519.652.862.86
326.443.403.40
348.453.603.60
601.694.814.81
519.696.196.19
487.534.744.74
513.981.621.62
231.211.651.65
365.444.604.60
328.393.163.16
323.405.345.34
356.423.593.59
489.605.415.41
382.513.993.99
246.192.152.15
414.521.511.51
376.873.493.49
369.372.552.55
420.465.495.49
446.564.364.36
345.914.404.40
285.262.742.74
242.062.642.64
341.485.275.27
385.783.883.88
340.403.603.60
480.883.563.56
328.423.503.50
421.574.284.28
316.363.103.10
293.122.812.81
424.552.592.59
363.514.364.36
354.504.184.18
312.421.221.22
466.575.135.13
256.322.702.70
418.483.583.58
353.472.172.17
625.54-0.32-0.32
383.454.324.32
462.551.331.33
417.464.584.58
575.672.962.96
295.200.740.74
363.452.872.87
443.534.444.44
293.323.803.80
432.504.934.93
380.473.273.27
295.302.182.18
309.353.433.43
388.453.893.89
368.373.833.83
436.473.623.62
223.321.821.82
470.605.355.35
408.574.084.08
411.605.185.18
447.524.634.63
406.533.663.66
363.514.924.92
351.452.552.55
250.312.932.93
405.284.364.36
291.792.552.55
566.663.943.94
359.812.832.83
333.502.482.48
374.452.182.18
296.373.893.89
366.382.442.44
292.30-0.14-0.14
570.624.944.94
417.314.824.82
371.403.213.21
379.893.463.46
304.322.752.75
453.522.242.24
568.705.165.16
412.306.206.20
434.974.994.99
345.203.843.84
418.203.243.24
468.778.248.24
325.443.813.81
586.663.053.05
389.576.126.12
392.523.673.67
509.577.877.87
280.173.963.96
440.592.392.39
331.464.794.79
459.797.697.69
464.994.784.78
382.444.244.24
313.351.901.90
528.633.583.58
353.381.401.40
404.904.004.00
381.394.054.05
518.576.936.93
426.512.872.87
367.152.162.16
381.504.584.58
222.682.752.75
411.553.753.75
313.383.083.08
247.252.132.13
344.213.743.74
365.893.663.66
411.985.375.37
464.501.561.56
377.493.293.29
527.718.338.33
271.302.932.93
201.231.241.24
282.711.271.27
393.492.912.91
617.734.684.68
428.626.726.72
231.260.850.85
377.282.522.52
435.524.814.81
424.243.463.46
495.495.555.55
521.615.125.12
303.751.671.67
630.545.785.78
640.816.406.40
436.563.843.84
348.242.872.87
508.502.642.64
269.303.513.51
340.423.253.25
387.275.235.23
413.955.115.11
304.404.454.45
281.321.861.86
311.173.843.84
377.403.923.92
267.742.012.01
345.453.853.85
461.584.144.14
347.423.943.94
265.703.073.07
308.392.672.67
415.584.664.66
434.016.766.76
401.474.754.75
423.355.275.27
518.602.772.77
444.553.783.78
431.513.103.10
378.414.514.51
508.965.155.15
323.423.383.38
356.434.994.99
484.965.205.20
405.503.623.62
342.382.712.71
424.884.154.15
416.524.544.54
555.685.375.37
359.435.615.61
651.835.865.86
387.496.346.34
326.402.182.18
354.623.483.48
355.484.754.75
316.282.832.83
357.453.663.66
409.965.765.76
289.794.714.71
352.373.033.03
438.573.673.67
236.283.013.01
635.166.706.70
315.384.154.15
316.312.562.56
385.123.793.79
502.734.644.64
319.843.803.80
355.534.174.17
585.637.257.25
394.483.573.57
534.507.927.92
496.505.205.20
539.769.289.28
408.894.474.47
379.464.374.37
333.443.883.88
429.443.303.30
357.424.464.46
530.474.954.95
455.215.535.53
284.793.473.47
288.733.583.58
424.894.694.69
338.124.014.01
379.504.564.56
642.836.426.42
452.564.034.03
370.413.513.51
549.504.394.39
281.363.353.35
391.231.741.74
228.343.173.17
389.414.934.93
364.461.471.47
522.576.976.97
315.402.302.30
323.262.952.95
302.173.343.34
399.312.532.53
471.484.004.00
325.464.524.52
378.403.573.57
252.792.572.57
289.363.113.11
413.524.584.58
425.504.644.64
333.313.193.19
380.964.464.46
411.465.575.57
385.422.282.28
496.591.731.73
459.292.492.49
653.765.495.49
291.354.004.00
429.503.323.32
362.452.632.63
472.613.683.68
431.403.953.95
299.805.125.12
646.795.845.84
440.465.475.47
502.521.421.42
315.373.543.54
392.894.994.99
342.814.264.26
282.372.872.87
415.325.205.20
417.514.734.73
502.313.273.27
267.342.402.40
501.643.893.89
377.283.683.68
417.535.835.83
511.718.508.50
380.383.743.74
404.303.813.81
437.794.594.59
230.271.841.84
371.872.832.83
446.286.156.15
340.403.603.60
406.944.504.50
530.355.245.24
381.454.554.55
480.612.802.80
319.392.532.53
311.824.534.53
337.473.903.90
415.495.515.51
548.214.754.75
398.471.741.74
231.261.251.25
455.313.433.43
388.474.624.62
544.372.892.89
260.302.902.90
419.423.873.87
421.794.894.89
357.794.124.12
497.045.715.71
335.752.802.80
440.884.134.13
419.576.336.33
386.544.524.52
462.462.642.64
513.646.186.18
327.444.274.27
367.502.952.95
418.474.074.07
328.392.952.95
462.815.325.32
343.432.652.65
429.483.573.57
376.463.203.20
341.525.925.92
458.933.743.74
390.444.474.47
514.335.445.44
332.431.511.51
380.393.153.15
308.342.572.57
406.534.554.55
315.373.913.91
407.814.364.36
349.462.802.80
446.553.963.96
347.423.903.90
395.554.704.70
371.872.292.29
496.85-2.72-2.72
377.463.563.56
357.423.573.57
360.483.573.57
535.517.787.78
382.373.633.63
224.331.581.58
474.365.415.41
433.365.045.04
252.742.852.85
395.934.834.83
524.015.065.06
459.703.513.51
287.753.453.45
238.333.443.44
319.381.521.52
397.572.212.21
403.273.853.85
433.606.446.44
374.495.405.40
199.252.412.41
449.334.814.81
550.536.546.54
224.180.130.13
362.432.872.87
624.775.865.86
311.342.692.69
258.323.193.19
413.482.602.60
363.514.444.44
400.364.124.12
503.475.725.72
459.576.996.99
436.584.464.46
557.655.115.11
255.363.683.68
546.117.127.12
355.484.894.89
274.394.734.73
303.434.964.96
458.486.006.00
358.463.063.06
432.932.212.21
378.494.124.12
398.934.734.73
520.614.364.36
328.384.804.80
235.313.163.16
453.335.785.78
473.475.745.74
445.683.113.11
348.412.272.27
490.646.646.64
377.244.484.48
531.596.506.50
490.057.817.81
720.696.256.25
519.779.459.45
292.343.423.42
282.775.255.25
376.462.612.61
375.383.923.92
525.748.898.89
331.173.483.48
435.585.485.48
489.026.606.60
450.604.904.90
292.343.443.44
468.194.014.01
466.925.685.68
419.915.455.45
297.312.372.37
473.004.064.06
394.544.654.65
590.416.676.67
407.566.646.64
329.363.813.81
530.634.864.86
540.455.725.72
357.573.983.98
324.434.214.21
432.057.077.07
447.446.996.99
364.453.633.63
359.381.871.87
253.312.792.79
487.586.046.04
291.342.552.55
468.343.783.78
326.232.332.33
235.622.472.47
421.574.064.06
301.350.610.61
329.364.334.33
412.285.095.09
394.323.973.97
280.334.484.48
505.758.988.98
288.374.444.44
388.305.125.12
250.212.002.00
561.8610.5410.54
511.423.983.98
421.912.602.60
389.284.854.85
304.382.182.18
455.215.445.44
340.884.734.73
507.591.711.71
323.232.742.74
341.454.454.45
388.524.314.31
577.724.784.78
272.383.563.56
453.513.383.38
470.595.725.72
431.492.872.87
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336.443.743.74
380.443.373.37
526.384.854.85
566.025.895.89
324.721.571.57
251.20-0.24-0.24
318.342.792.79
421.452.942.94
332.282.782.78
474.648.808.80