Basic Information
ID: ALA1794299
Type: Functional
Description: PUBCHEM_BIOASSAY: Inhibitors of DNA Polymerase Beta: Hit validation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485311]
Activity Charts
Bioactivity
Activity Types for Assay ALA1794299
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 308.29 | 3.71 | 3.71 |
| 327.37 | 2.86 | 2.86 |
| 342.38 | 2.83 | 2.83 |
| 292.32 | 1.88 | 1.88 |
| 358.38 | 2.06 | 2.06 |
| 404.49 | 4.80 | 4.80 |
| 286.28 | 2.82 | 2.82 |
| 422.44 | 5.33 | 5.33 |
| 282.30 | 3.10 | 3.10 |
| 375.45 | 4.72 | 4.72 |
| 290.34 | 2.48 | 2.48 |
| 371.33 | 4.42 | 4.42 |
| 310.31 | 2.40 | 2.40 |
| 287.34 | 3.46 | 3.46 |
| 404.26 | 3.76 | 3.76 |
| 419.44 | 4.81 | 4.81 |
| 448.58 | 4.92 | 4.92 |
| 397.78 | 3.43 | 3.43 |
| 303.70 | 3.44 | 3.44 |
| 348.40 | 4.20 | 4.20 |
| 444.47 | 3.08 | 3.08 |
| 412.56 | 2.37 | 2.37 |
| 326.74 | 2.88 | 2.88 |
| 385.45 | 3.36 | 3.36 |
| 477.33 | 1.22 | 1.22 |
| 537.45 | 4.90 | 4.90 |
| 378.44 | 2.52 | 2.52 |
| 284.27 | 2.88 | 2.88 |
| 392.51 | 5.14 | 5.14 |
| 521.37 | 5.67 | 5.67 |
| 391.33 | 5.08 | 5.08 |
| 561.66 | ||
| 449.87 | 2.60 | 2.60 |
| 308.45 | 4.43 | 4.43 |
| 253.30 | 3.19 | 3.19 |
| 432.48 | 2.46 | 2.46 |
| 287.31 | 2.07 | 2.07 |
| 458.52 | 2.54 | 2.54 |
| 412.40 | 2.42 | 2.42 |
| 286.29 | 2.20 | 2.20 |
| 390.24 | 3.91 | 3.91 |
| 389.44 | 2.63 | 2.63 |
| 413.48 | 2.41 | 2.41 |
| 446.32 | 4.36 | 4.36 |
| 351.36 | 4.17 | 4.17 |
| 396.47 | 4.20 | 4.20 |
| 276.30 | 3.89 | 3.89 |
| 277.39 | 2.82 | 2.82 |
| 450.52 | 3.33 | 3.33 |
| 475.53 | 2.67 | 2.67 |
| 427.51 | 2.66 | 2.66 |
| 338.34 | 3.76 | 3.76 |
| 382.42 | 4.51 | 4.51 |
| 380.30 | 4.43 | 4.43 |
| 539.71 | 4.12 | 4.12 |
| 300.31 | 3.12 | 3.12 |
| 509.98 | 1.95 | 1.95 |
| 304.40 | 3.25 | 3.25 |
| 476.41 | 4.20 | 4.20 |
| 280.35 | 4.78 | 4.78 |
| 295.43 | 3.51 | 3.51 |
| 428.51 | 2.48 | 2.48 |
| 294.31 | 3.13 | 3.13 |
| 448.55 | 4.34 | 4.34 |
| 415.49 | 5.75 | 5.75 |
| 498.63 | 4.67 | 4.67 |
| 499.60 | 4.93 | 4.93 |
| 290.37 | 3.72 | 3.72 |
| 381.39 | 4.36 | 4.36 |
| 252.72 | 3.91 | 3.91 |
| 383.21 | 4.03 | 4.03 |
| 341.39 | 2.62 | 2.62 |
| 303.31 | 1.91 | 1.91 |
| 444.47 | 2.92 | 2.92 |
| 453.40 | 4.41 | 4.41 |
| 460.52 | 4.22 | 4.22 |
| 476.49 | 2.63 | 2.63 |
| 467.57 | 4.09 | 4.09 |
| 459.56 | 5.30 | 5.30 |
| 370.79 | 3.50 | 3.50 |
| 346.34 | 2.19 | 2.19 |
| 387.53 | 3.87 | 3.87 |
| 281.31 | 1.72 | 1.72 |
| 437.40 | 2.87 | 2.87 |
| 396.41 | 3.22 | 3.22 |
| 326.40 | 2.80 | 2.80 |
| 356.38 | 3.93 | 3.93 |
| 465.51 | 3.89 | 3.89 |
| 452.52 | 2.11 | 2.11 |
| 413.39 | 4.73 | 4.73 |
| 321.34 | 3.06 | 3.06 |
| 551.79 | 3.53 | 3.53 |
| 435.47 | 2.88 | 2.88 |
| 378.88 | 3.26 | 3.26 |
| 259.33 | 3.13 | 3.13 |
| 405.40 | 5.46 | 5.46 |
| 464.40 | 6.65 | 6.65 |
| 425.47 | 3.00 | 3.00 |
| 477.31 | 5.27 | 5.27 |
| 342.36 | 4.24 | 4.24 |
| 371.42 | 2.19 | 2.19 |
| 414.49 | 5.11 | 5.11 |
| 354.39 | 2.72 | 2.72 |
| 367.22 | 4.33 | 4.33 |
| 440.55 | 4.41 | 4.41 |
| 370.37 | 5.10 | 5.10 |
| 493.54 | 3.78 | 3.78 |
| 319.32 | 3.69 | 3.69 |
| 361.46 | 3.34 | 3.34 |
| 424.53 | 2.77 | 2.77 |
| 497.57 | 2.86 | 2.86 |
| 273.29 | 2.44 | 2.44 |
| 376.37 | 4.01 | 4.01 |
| 489.58 | 5.31 | 5.31 |
| 374.42 | 3.59 | 3.59 |
| 315.42 | 3.37 | 3.37 |
| 487.57 | 4.81 | 4.81 |
| 412.51 | 3.49 | 3.49 |
| 412.54 | 4.14 | 4.14 |
| 350.40 | 4.16 | 4.16 |
| 495.61 | 5.50 | 5.50 |
| 330.34 | 3.67 | 3.67 |
| 398.28 | 3.30 | 3.30 |
| 351.43 | 3.72 | 3.72 |
| 427.57 | 2.29 | 2.29 |
| 498.95 | 4.04 | 4.04 |
| 326.38 | 3.41 | 3.41 |
| 397.91 | 3.75 | 3.75 |
| 482.24 | 2.53 | 2.53 |
| 465.56 | 3.91 | 3.91 |
| 357.37 | 3.72 | 3.72 |
| 397.55 | 5.23 | 5.23 |
| 313.43 | 3.32 | 3.32 |
| 476.41 | 4.20 | 4.20 |
| 345.45 | 3.38 | 3.38 |
| 288.36 | 3.10 | 3.10 |
| 342.46 | 3.21 | 3.21 |
| 461.47 | 3.58 | 3.58 |
| 292.29 | 4.22 | 4.22 |
| 360.43 | 3.22 | 3.22 |
| 375.48 | 3.39 | 3.39 |
| 446.42 | 2.89 | 2.89 |
| 283.28 | 3.41 | 3.41 |
| 444.53 | 5.17 | 5.17 |
| 409.51 | 3.53 | 3.53 |
| 448.49 | 5.59 | 5.59 |
| 335.39 | 4.51 | 4.51 |
| 425.56 | 2.63 | 2.63 |
| 352.42 | 3.25 | 3.25 |
| 374.40 | 1.60 | 1.60 |
| 353.77 | 4.34 | 4.34 |
| 369.38 | 1.39 | 1.39 |
| 362.35 | 1.16 | 1.16 |
| 492.51 | 3.24 | 3.24 |
| 416.48 | 4.53 | 4.53 |
| 469.52 | 3.45 | 3.45 |
| 315.41 | 3.75 | 3.75 |
| 432.51 | 4.01 | 4.01 |
| 483.55 | 2.26 | 2.26 |
| 439.59 | 5.29 | 5.29 |
| 477.50 | 4.43 | 4.43 |
| 448.49 | 5.41 | 5.41 |
| 384.44 | 1.56 | 1.56 |
| 497.65 | 6.45 | 6.45 |
| 485.51 | 2.14 | 2.14 |
| 524.70 | 4.54 | 4.54 |
| 336.39 | 3.53 | 3.53 |
| 347.39 | 2.87 | 2.87 |
| 405.48 | 3.68 | 3.68 |
| 559.67 | 4.02 | 4.02 |
| 329.36 | 4.45 | 4.45 |
| 380.40 | 5.13 | 5.13 |
| 480.47 | 1.57 | 1.57 |
| 307.31 | 2.67 | 2.67 |
| 399.49 | 6.05 | 6.05 |
| 355.35 | 1.91 | 1.91 |
| 308.37 | 3.36 | 3.36 |
| 358.85 | 4.53 | 4.53 |
| 324.34 | 2.79 | 2.79 |
| 276.32 | 3.15 | 3.15 |
| 396.45 | 1.73 | 1.73 |
| 354.39 | 2.85 | 2.85 |
| 395.48 | 3.76 | 3.76 |
| 459.46 | 3.23 | 3.23 |
| 312.44 | 3.20 | 3.20 |
| 420.47 | 5.35 | 5.35 |
| 396.86 | 4.15 | 4.15 |
| 381.37 | 4.30 | 4.30 |
| 451.45 | 5.00 | 5.00 |
| 320.37 | 3.79 | 3.79 |
| 458.59 | 4.59 | 4.59 |
| 433.61 | 5.21 | 5.21 |
| 410.41 | 2.94 | 2.94 |
| 400.42 | 4.46 | 4.46 |
| 301.39 | 3.36 | 3.36 |
| 387.39 | 3.73 | 3.73 |
| 378.45 | 1.38 | 1.38 |
| 307.31 | 4.02 | 4.02 |
| 542.59 | 3.91 | 3.91 |
| 365.41 | 3.03 | 3.03 |
| 475.94 | 4.26 | 4.26 |
| 445.32 | 2.59 | 2.59 |
| 373.82 | 4.69 | 4.69 |
| 306.41 | 3.66 | 3.66 |
| 417.49 | 5.11 | 5.11 |
| 404.49 | 1.77 | 1.77 |
| 351.36 | 3.55 | 3.55 |
| 406.41 | 2.67 | 2.67 |
| 331.40 | 2.55 | 2.55 |
| 386.83 | 4.66 | 4.66 |
| 397.46 | 3.84 | 3.84 |
| 382.51 | 2.97 | 2.97 |
| 492.56 | 3.28 | 3.28 |
| 421.45 | 3.25 | 3.25 |
| 465.60 | 1.67 | 1.67 |
| 289.29 | 1.68 | 1.68 |
| 331.35 | 2.28 | 2.28 |
| 564.09 | 4.66 | 4.66 |
| 385.45 | 2.35 | 2.35 |
| 284.36 | 3.65 | 3.65 |
| 450.32 | 5.67 | 5.67 |
| 337.36 | 3.47 | 3.47 |
| 399.53 | 2.07 | 2.07 |
| 274.35 | 3.14 | 3.14 |
| 349.41 | 2.48 | 2.48 |
| 508.64 | 3.84 | 3.84 |
| 449.53 | 3.34 | 3.34 |
| 310.40 | 2.49 | 2.49 |
| 388.42 | 2.39 | 2.39 |
| 415.45 | 3.84 | 3.84 |
| 292.34 | 3.25 | 3.25 |
| 268.25 | 1.91 | 1.91 |
| 461.54 | 5.13 | 5.13 |
| 429.51 | 4.41 | 4.41 |
| 361.81 | 4.70 | 4.70 |
| 336.39 | 3.59 | 3.59 |
| 325.39 | 3.93 | 3.93 |
| 288.32 | 3.18 | 3.18 |
| 392.39 | 2.27 | 2.27 |
| 501.57 | 4.33 | 4.33 |
| 424.48 | 4.13 | 4.13 |
| 288.69 | 3.48 | 3.48 |
| 281.36 | 3.70 | 3.70 |
| 527.00 | 3.30 | 3.30 |
| 339.38 | 2.36 | 2.36 |
| 377.43 | 3.20 | 3.20 |
| 328.42 | 3.15 | 3.15 |
| 325.35 | 1.97 | 1.97 |
| 463.99 | 4.15 | 4.15 |
| 264.24 | -0.27 | -0.27 |
| 439.49 | 3.13 | 3.13 |
| 331.38 | 3.56 | 3.56 |
| 524.62 | 2.98 | 2.98 |
| 452.54 | 4.10 | 4.10 |