ID: ALA1794316
Type: Functional
Description: PUBCHEM_BIOASSAY: SAR Analysis of small molecule inhibitors of T-cell specific antigen receptor-induced NF-kB activation in a 697B cell line using a luminescence assay - Set 2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID435003, AID435012, AID465]
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA1794316
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
330.34 | 2.19 | 2.19 |
402.54 | 5.85 | 5.85 |
374.48 | 5.03 | 5.03 |
362.47 | 5.07 | 5.07 |
334.42 | 4.25 | 4.25 |
334.42 | 4.34 | 4.34 |
354.84 | 4.60 | 4.60 |
403.31 | 5.64 | 5.64 |
350.42 | 3.95 | 3.95 |
349.43 | 3.62 | 3.62 |
405.54 | 5.18 | 5.18 |
334.42 | 4.29 | 4.29 |
350.42 | 3.95 | 3.95 |
260.25 | 3.06 | 3.06 |
378.82 | 3.24 | 3.24 |
376.50 | 5.46 | 5.46 |
260.25 | 3.06 | 3.06 |
342.40 | 4.32 | 4.32 |
335.75 | 3.69 | 3.69 |
342.38 | 2.93 | 2.93 |
377.49 | 4.40 | 4.40 |
428.44 | 5.02 | 5.02 |
350.29 | 3.64 | 3.64 |
301.39 | 3.05 | 3.05 |
346.45 | 3.56 | 3.56 |
283.24 | 2.99 | 2.99 |
320.39 | 3.86 | 3.86 |
304.29 | 2.75 | 2.75 |
276.25 | 2.84 | 2.84 |
260.25 | 3.06 | 3.06 |
287.36 | 2.71 | 2.71 |
301.39 | 3.10 | 3.10 |
430.08 | 4.03 | 4.03 |
368.86 | 4.99 | 4.99 |
350.42 | 3.81 | 3.81 |
350.29 | 3.64 | 3.64 |
350.29 | 3.64 | 3.64 |
450.47 | 4.78 | 4.78 |
355.31 | 3.59 | 3.59 |
274.23 | 2.64 | 2.64 |
354.84 | 4.60 | 4.60 |
392.80 | 2.76 | 2.76 |
273.34 | 2.45 | 2.45 |
386.47 | 4.19 | 4.19 |
446.50 | 3.42 | 3.42 |
320.39 | 3.95 | 3.95 |
378.82 | 3.24 | 3.24 |
274.23 | 2.64 | 2.64 |
314.22 | 3.77 | 3.77 |
445.43 | 5.24 | 5.24 |
231.25 | 1.42 | 1.42 |
420.85 | 5.60 | 5.60 |
257.21 | 2.31 | 2.31 |
329.44 | 3.84 | 3.84 |
315.29 | 2.35 | 2.35 |
428.49 | 4.41 | 4.41 |
329.44 | 3.88 | 3.88 |
465.30 | 5.71 | 5.71 |
416.43 | 4.95 | 4.95 |
364.32 | 3.95 | 3.95 |
412.49 | 4.79 | 4.79 |
431.40 | 4.85 | 4.85 |
334.42 | 4.19 | 4.19 |
311.27 | 1.09 | 1.09 |
364.45 | 4.34 | 4.34 |
348.45 | 4.64 | 4.64 |
430.42 | 4.67 | 4.67 |
447.54 | 5.76 | 5.76 |
414.46 | 5.73 | 5.73 |
322.36 | 3.17 | 3.17 |
276.25 | 2.76 | 2.76 |
334.42 | 4.11 | 4.11 |
274.23 | 2.38 | 2.38 |
379.33 | 4.26 | 4.26 |
329.44 | 3.88 | 3.88 |
394.47 | 4.21 | 4.21 |
376.50 | 5.32 | 5.32 |
260.25 | 3.06 | 3.06 |