Basic Information
ID: ALA1794327
Type: Functional
Description: PUBCHEM_BIOASSAY: Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504720, AID504743]
Activity Charts
Bioactivity
Activity Types for Assay ALA1794327
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 350.40 | 2.78 | 2.78 |
| 428.44 | 2.54 | 2.54 |
| 368.30 | 2.01 | 2.01 |
| 220.18 | 1.02 | 1.02 |
| 244.25 | 2.68 | 2.68 |
| 297.74 | 4.47 | 4.47 |
| 345.38 | 2.97 | 2.97 |
| 354.36 | 3.79 | 3.79 |
| 291.73 | 3.70 | 3.70 |
| 280.37 | 3.58 | 3.58 |
| 315.38 | 3.70 | 3.70 |
| 290.26 | 1.92 | 1.92 |
| 271.28 | 0.94 | 0.94 |
| 206.63 | -0.39 | -0.39 |
| 238.31 | 3.32 | 3.32 |
| 292.29 | 4.02 | 4.02 |
| 406.46 | 2.13 | 2.13 |
| 332.16 | 2.56 | 2.56 |
| 277.33 | 3.67 | 3.67 |
| 279.34 | 3.59 | 3.59 |
| 363.39 | 5.12 | 5.12 |
| 413.45 | 5.41 | 5.41 |
| 253.30 | 2.72 | 2.72 |
| 284.27 | 3.21 | 3.21 |
| 343.34 | 3.92 | 3.92 |
| 334.47 | 3.42 | 3.42 |
| 335.41 | 3.31 | 3.31 |
| 344.37 | 3.63 | 3.63 |
| 420.49 | 2.76 | 2.76 |
| 312.29 | 4.21 | 4.21 |
| 323.31 | 2.58 | 2.58 |
| 370.33 | 5.71 | 5.71 |
| 359.37 | 2.04 | 2.04 |
| 288.33 | 2.38 | 2.38 |
| 269.28 | 4.74 | 4.74 |
| 427.96 | 3.66 | 3.66 |
| 300.25 | 4.34 | 4.34 |
| 522.01 | 5.27 | 5.27 |
| 485.99 | 3.18 | 3.18 |
| 288.40 | 3.61 | 3.61 |
| 348.49 | 3.13 | 3.13 |
| 395.38 | 1.81 | 1.81 |
| 375.38 | 2.37 | 2.37 |
| 433.42 | 2.49 | 2.49 |
| 422.46 | 4.39 | 4.39 |
| 429.51 | 4.47 | 4.47 |
| 403.45 | 3.69 | 3.69 |
| 430.88 | 1.85 | 1.85 |
| 255.25 | 4.43 | 4.43 |
| 354.40 | 2.23 | 2.23 |
| 410.35 | 4.32 | 4.32 |
| 375.45 | 4.40 | 4.40 |
| 404.45 | 3.19 | 3.19 |
| 311.34 | 2.43 | 2.43 |
| 303.41 | 4.23 | 4.23 |
| 331.40 | 3.99 | 3.99 |
| 341.84 | 3.28 | 3.28 |
| 354.57 | 4.67 | 4.67 |
| 424.48 | 2.48 | 2.48 |
| 427.51 | 4.25 | 4.25 |
| 427.48 | 5.72 | 5.72 |
| 422.32 | 3.99 | 3.99 |
| 273.30 | 3.32 | 3.32 |
| 272.33 | 2.80 | 2.80 |
| 286.36 | 2.52 | 2.52 |
| 447.00 | 3.20 | 3.20 |
| 444.94 | 4.54 | 4.54 |
| 405.57 | 3.60 | 3.60 |
| 359.45 | 4.54 | 4.54 |
| 387.49 | 3.44 | 3.44 |
| 308.34 | 3.00 | 3.00 |
| 363.42 | 3.10 | 3.10 |
| 435.76 | 4.93 | 4.93 |
| 423.47 | 2.43 | 2.43 |
| 442.49 | 1.93 | 1.93 |
| 373.37 | 4.37 | 4.37 |
| 377.43 | 4.35 | 4.35 |
| 438.37 | 2.95 | 2.95 |
| 326.36 | 1.29 | 1.29 |
| 348.41 | 2.80 | 2.80 |
| 469.01 | 4.32 | 4.32 |
| 423.49 | 4.52 | 4.52 |
| 299.34 | 3.43 | 3.43 |
| 304.37 | 4.73 | 4.73 |
| 269.26 | 1.49 | 1.49 |
| 286.28 | 1.61 | 1.61 |
| 328.42 | 5.16 | 5.16 |
| 322.32 | 2.50 | 2.50 |
| 375.43 | 4.81 | 4.81 |
| 329.31 | 2.00 | 2.00 |
| 408.85 | 3.01 | 3.01 |
| 251.33 | 3.65 | 3.65 |
| 368.44 | 3.59 | 3.59 |
| 399.50 | 3.32 | 3.32 |
| 375.45 | 4.88 | 4.88 |
| 325.32 | 1.69 | 1.69 |
| 255.25 | 4.43 | 4.43 |
| 285.73 | 5.25 | 5.25 |
| 348.43 | 3.62 | 3.62 |
| 358.42 | 3.00 | 3.00 |
| 275.31 | 3.77 | 3.77 |
| 297.35 | 3.82 | 3.82 |
| 372.39 | 1.63 | 1.63 |
| 457.53 | 3.12 | 3.12 |
| 476.51 | 6.30 | 6.30 |
| 300.34 | 2.56 | 2.56 |
| 420.73 | 3.93 | 3.93 |
| 454.50 | 4.78 | 4.78 |
| 403.23 | 4.23 | 4.23 |
| 417.47 | 3.24 | 3.24 |
| 302.36 | 2.77 | 2.77 |
| 415.43 | 3.24 | 3.24 |
| 307.31 | 3.01 | 3.01 |
| 371.39 | 3.98 | 3.98 |
| 319.41 | 4.25 | 4.25 |
| 441.50 | 4.67 | 4.67 |
| 492.57 | 4.37 | 4.37 |
| 375.38 | 3.23 | 3.23 |
| 345.81 | 4.33 | 4.33 |
| 472.91 | 2.37 | 2.37 |
| 312.75 | 4.63 | 4.63 |
| 349.39 | 3.70 | 3.70 |
| 333.34 | 3.28 | 3.28 |
| 386.45 | 3.44 | 3.44 |
| 400.46 | 3.27 | 3.27 |
| 436.47 | 2.08 | 2.08 |
| 366.40 | 4.37 | 4.37 |
| 285.32 | 3.50 | 3.50 |
| 481.57 | 3.25 | 3.25 |
| 299.33 | 3.94 | 3.94 |
| 327.39 | 4.61 | 4.61 |
| 243.27 | 2.74 | 2.74 |
| 426.47 | 5.33 | 5.33 |
| 415.84 | 4.98 | 4.98 |
| 268.70 | 3.92 | 3.92 |
| 272.33 | 2.68 | 2.68 |
| 435.28 | 5.18 | 5.18 |
| 512.52 | 5.04 | 5.04 |
| 260.30 | 3.18 | 3.18 |
| 487.57 | 4.61 | 4.61 |
| 348.36 | 2.85 | 2.85 |
| 365.23 | 3.90 | 3.90 |
| 256.27 | 3.73 | 3.73 |
| 284.34 | 3.27 | 3.27 |
| 337.40 | 3.86 | 3.86 |
| 395.33 | 2.30 | 2.30 |
| 340.81 | 4.53 | 4.53 |
| 384.49 | 3.59 | 3.59 |
| 401.47 | 3.16 | 3.16 |
| 392.46 | 3.91 | 3.91 |
| 396.43 | 3.08 | 3.08 |
| 436.47 | 4.43 | 4.43 |
| 295.36 | 3.91 | 3.91 |
| 342.37 | 4.83 | 4.83 |
| 445.44 | 5.88 | 5.88 |
| 267.38 | 2.96 | 2.96 |
| 394.35 | 3.65 | 3.65 |
| 286.36 | 2.99 | 2.99 |
| 355.40 | 4.60 | 4.60 |
| 402.43 | 4.67 | 4.67 |
| 420.52 | 2.39 | 2.39 |
| 267.28 | 3.08 | 3.08 |
| 239.30 | 3.21 | 3.21 |
| 356.40 | 2.15 | 2.15 |
| 310.31 | 2.40 | 2.40 |
| 340.36 | 0.87 | 0.87 |
| 316.36 | 2.00 | 2.00 |
| 421.48 | 5.82 | 5.82 |
| 269.28 | 4.74 | 4.74 |
| 400.46 | 3.55 | 3.55 |
| 313.31 | 4.75 | 4.75 |
| 268.34 | 4.04 | 4.04 |
| 371.44 | 3.15 | 3.15 |
| 266.28 | 3.64 | 3.64 |
| 422.44 | 5.25 | 5.25 |
| 447.93 | 5.00 | 5.00 |
| 471.92 | 3.04 | 3.04 |
| 451.92 | 6.07 | 6.07 |
| 363.42 | 4.09 | 4.09 |
| 234.17 | 1.23 | 1.23 |
| 297.31 | 3.73 | 3.73 |
| 410.45 | 4.23 | 4.23 |
| 389.84 | 4.51 | 4.51 |
| 298.37 | 3.36 | 3.36 |
| 404.50 | 3.67 | 3.67 |
| 474.49 | 4.59 | 4.59 |
| 283.35 | 0.58 | 0.58 |
| 340.32 | 0.71 | 0.71 |
| 366.42 | 3.22 | 3.22 |
| 288.35 | 4.06 | 4.06 |
| 300.30 | 3.33 | 3.33 |
| 294.40 | 3.83 | 3.83 |
| 476.37 | 3.31 | 3.31 |
| 455.94 | 5.63 | 5.63 |
| 272.33 | 2.68 | 2.68 |
| 409.63 | 4.81 | 4.81 |
| 331.37 | 2.99 | 2.99 |
| 367.47 | 3.77 | 3.77 |
| 383.48 | 5.63 | 5.63 |
| 486.57 | 4.64 | 4.64 |
| 339.39 | 2.95 | 2.95 |
| 308.38 | 3.61 | 3.61 |
| 433.54 | 2.51 | 2.51 |
| 309.32 | 3.05 | 3.05 |
| 445.55 | 4.36 | 4.36 |
| 336.37 | 4.37 | 4.37 |
| 537.62 | 6.32 | 6.32 |
| 269.26 | 0.93 | 0.93 |
| 293.33 | 4.65 | 4.65 |
| 462.58 | 4.42 | 4.42 |
| 354.41 | -0.44 | -0.44 |
| 302.28 | 1.32 | 1.32 |
| 319.43 | 3.47 | 3.47 |
| 402.48 | 3.75 | 3.75 |
| 399.45 | 4.81 | 4.81 |
| 294.31 | 3.88 | 3.88 |
| 388.36 | 2.07 | 2.07 |
| 304.30 | 4.02 | 4.02 |
| 335.36 | 3.31 | 3.31 |
| 379.44 | 2.70 | 2.70 |
| 300.34 | 2.97 | 2.97 |
| 513.38 | 3.63 | 3.63 |
| 304.29 | 2.35 | 2.35 |
| 286.36 | 3.07 | 3.07 |
| 322.75 | 3.75 | 3.75 |
| 337.81 | 3.89 | 3.89 |
| 253.31 | 2.89 | 2.89 |
| 406.91 | 5.01 | 5.01 |
| 311.39 | 4.65 | 4.65 |
| 300.39 | 2.11 | 2.11 |
| 286.36 | 3.07 | 3.07 |
| 472.50 | 3.16 | 3.16 |
| 274.33 | 3.67 | 3.67 |
| 451.43 | 2.09 | 2.09 |
| 337.38 | 3.29 | 3.29 |
| 328.32 | 3.64 | 3.64 |
| 358.35 | 1.50 | 1.50 |
| 361.40 | 4.50 | 4.50 |
| 234.25 | 1.65 | 1.65 |
| 289.34 | 4.17 | 4.17 |
| 363.40 | 3.49 | 3.49 |
| 423.51 | 4.63 | 4.63 |
| 293.32 | 3.61 | 3.61 |
| 352.46 | 4.61 | 4.61 |
| 388.43 | 2.55 | 2.55 |
| 315.33 | 3.65 | 3.65 |
| 343.48 | 4.28 | 4.28 |
| 369.25 | 5.05 | 5.05 |
| 238.24 | 3.05 | 3.05 |
| 373.80 | 3.76 | 3.76 |
| 333.39 | 3.28 | 3.28 |
| 321.34 | 2.92 | 2.92 |
| 247.30 | 3.58 | 3.58 |
| 387.48 | 4.57 | 4.57 |
| 361.36 | 2.50 | 2.50 |
| 426.47 | 2.22 | 2.22 |
| 389.84 | 4.40 | 4.40 |
| 281.31 | 3.17 | 3.17 |
| 329.40 | 4.38 | 4.38 |
| 398.25 | 5.35 | 5.35 |
| 357.46 | 4.87 | 4.87 |
| 338.32 | 4.12 | 4.12 |
| 355.30 | 2.38 | 2.38 |
| 442.49 | 2.01 | 2.01 |
| 308.34 | 3.52 | 3.52 |
| 358.36 | 4.65 | 4.65 |
| 449.94 | 5.83 | 5.83 |
| 342.42 | 2.50 | 2.50 |
| 342.42 | 3.89 | 3.89 |
| 336.78 | 5.28 | 5.28 |
| 237.26 | 4.29 | 4.29 |
| 413.46 | 3.63 | 3.63 |
| 409.49 | 4.20 | 4.20 |
| 255.39 | 3.39 | 3.39 |
| 289.34 | 4.17 | 4.17 |
| 350.42 | 4.36 | 4.36 |
| 317.35 | 4.21 | 4.21 |
| 349.39 | 2.74 | 2.74 |
| 334.15 | 5.19 | 5.19 |
| 267.29 | 2.65 | 2.65 |
| 427.47 | 6.23 | 6.23 |
| 300.38 | 2.91 | 2.91 |
| 328.82 | 4.25 | 4.25 |
| 365.43 | 2.88 | 2.88 |
| 301.35 | 4.12 | 4.12 |
| 406.47 | 4.21 | 4.21 |
| 437.11 | 5.19 | 5.19 |
| 312.39 | 3.46 | 3.46 |
| 320.32 | 4.83 | 4.83 |
| 364.47 | 4.79 | 4.79 |
| 443.57 | 2.95 | 2.95 |
| 500.96 | 4.77 | 4.77 |
| 309.37 | 5.27 | 5.27 |
| 272.74 | 2.79 | 2.79 |
| 280.42 | 2.86 | 2.86 |
| 385.81 | 5.01 | 5.01 |
| 366.45 | 3.07 | 3.07 |
| 343.39 | 4.75 | 4.75 |
| 396.38 | 3.64 | 3.64 |
| 387.39 | 4.96 | 4.96 |
| 374.49 | 3.91 | 3.91 |
| 296.24 | 3.01 | 3.01 |
| 398.44 | 4.70 | 4.70 |
| 466.50 | 2.51 | 2.51 |
| 444.54 | 2.18 | 2.18 |
| 402.25 | 3.07 | 3.07 |
| 339.42 | 4.07 | 4.07 |
| 446.33 | 4.11 | 4.11 |
| 354.84 | 2.88 | 2.88 |
| 368.23 | 3.88 | 3.88 |
| 381.42 | 3.10 | 3.10 |
| 300.30 | -0.13 | -0.13 |
| 325.39 | 3.92 | 3.92 |
| 368.39 | 3.86 | 3.86 |
| 409.96 | 4.60 | 4.60 |
| 364.52 | 3.84 | 3.84 |
| 447.50 | 1.93 | 1.93 |
| 379.39 | 1.86 | 1.86 |
| 413.45 | 5.41 | 5.41 |
| 334.49 | 3.83 | 3.83 |
| 370.41 | 4.03 | 4.03 |
| 340.38 | 4.02 | 4.02 |
| 317.32 | 2.09 | 2.09 |
| 397.38 | 4.78 | 4.78 |
| 403.40 | 2.01 | 2.01 |
| 216.26 | 0.24 | 0.24 |
| 371.23 | 4.37 | 4.37 |
| 453.52 | 4.71 | 4.71 |
| 410.41 | 4.03 | 4.03 |
| 311.30 | 3.09 | 3.09 |
| 305.72 | 1.59 | 1.59 |
| 371.40 | 3.76 | 3.76 |
| 469.34 | 4.90 | 4.90 |
| 392.85 | 4.40 | 4.40 |
| 501.77 | 4.42 | 4.42 |
| 443.51 | 4.03 | 4.03 |
| 381.64 | 4.53 | 4.53 |
| 373.48 | 3.87 | 3.87 |
| 252.30 | 3.95 | 3.95 |
| 467.32 | 3.76 | 3.76 |
| 307.34 | 2.06 | 2.06 |
| 429.57 | 4.56 | 4.56 |
| 330.39 | 5.72 | 5.72 |
| 316.39 | 4.27 | 4.27 |
| 272.22 | 2.58 | 2.58 |
| 359.31 | 3.50 | 3.50 |
| 368.41 | 5.22 | 5.22 |
| 332.41 | 3.10 | 3.10 |
| 345.47 | 2.82 | 2.82 |
| 316.36 | 4.94 | 4.94 |
| 271.71 | 4.94 | 4.94 |
| 396.45 | 3.53 | 3.53 |
| 278.17 | 0.72 | 0.72 |
| 415.45 | 4.05 | 4.05 |
| 290.24 | 3.20 | 3.20 |
| 378.48 | 4.48 | 4.48 |
| 335.37 | 3.18 | 3.18 |
| 393.41 | 5.03 | 5.03 |
| 330.34 | 3.78 | 3.78 |
| 370.43 | 5.96 | 5.96 |
| 413.48 | 4.45 | 4.45 |
| 297.34 | 3.99 | 3.99 |
| 460.63 | 3.84 | 3.84 |
| 361.40 | 4.36 | 4.36 |
| 330.34 | 3.65 | 3.65 |
| 384.45 | 5.85 | 5.85 |
| 347.33 | 2.09 | 2.09 |
| 476.51 | 6.30 | 6.30 |
| 413.46 | 1.02 | 1.02 |
| 303.30 | 2.61 | 2.61 |
| 474.49 | 4.59 | 4.59 |
| 308.39 | 1.67 | 1.67 |
| 286.25 | 2.16 | 2.16 |
| 247.34 | 4.32 | 4.32 |
| 497.57 | 2.83 | 2.83 |
| 470.54 | 4.61 | 4.61 |
| 313.36 | 3.28 | 3.28 |
| 300.31 | 3.74 | 3.74 |
| 292.30 | 3.59 | 3.59 |
| 383.50 | 3.62 | 3.62 |
| 351.32 | 3.52 | 3.52 |
| 500.61 | 2.71 | 2.71 |
| 302.38 | 2.74 | 2.74 |
| 322.27 | 2.28 | 2.28 |
| 290.32 | 3.70 | 3.70 |
| 439.52 | 1.94 | 1.94 |
| 256.27 | 2.46 | 2.46 |
| 297.34 | 2.19 | 2.19 |
| 469.93 | 1.58 | 1.58 |
| 461.32 | 4.40 | 4.40 |
| 1422.72 | ||
| 418.54 | 4.07 | 4.07 |
| 448.52 | 2.87 | 2.87 |
| 286.19 | 3.66 | 3.66 |
| 467.49 | 0.81 | 0.81 |
| 399.21 | 1.23 | 1.23 |
| 319.36 | 4.18 | 4.18 |
| 413.46 | 1.02 | 1.02 |
| 251.29 | 4.32 | 4.32 |
| 527.42 | 3.63 | 3.63 |
| 444.56 | 1.64 | 1.64 |
| 236.22 | -0.01 | -0.01 |
| 456.55 | 3.03 | 3.03 |
| 467.55 | 2.94 | 2.94 |
| 479.37 | 2.92 | 2.92 |
| 311.36 | 2.44 | 2.44 |
| 335.32 | 4.21 | 4.21 |
| 353.34 | 2.96 | 2.96 |
| 381.45 | 2.25 | 2.25 |
| 271.32 | 3.86 | 3.86 |
| 344.84 | 4.25 | 4.25 |
| 281.70 | 2.20 | 2.20 |
| 311.43 | 4.06 | 4.06 |
| 339.48 | 4.84 | 4.84 |
| 391.43 | 2.98 | 2.98 |
| 387.44 | 3.43 | 3.43 |
| 424.45 | 3.30 | 3.30 |
| 312.76 | 4.41 | 4.41 |
| 465.52 | 1.97 | 1.97 |
| 287.39 | 3.13 | 3.13 |
| 260.29 | 3.34 | 3.34 |
| 360.85 | 5.28 | 5.28 |
| 342.42 | 2.17 | 2.17 |
| 404.86 | 4.94 | 4.94 |
| 467.49 | 0.81 | 0.81 |
| 305.38 | 4.95 | 4.95 |
| 342.35 | 4.30 | 4.30 |
| 408.48 | 4.47 | 4.47 |
| 433.49 | 1.99 | 1.99 |
| 318.38 | 3.06 | 3.06 |
| 307.35 | 3.86 | 3.86 |
| 259.24 | 3.18 | 3.18 |
| 277.28 | 1.56 | 1.56 |
| 497.57 | 2.83 | 2.83 |
| 231.25 | 2.62 | 2.62 |
| 347.38 | 3.11 | 3.11 |
| 396.47 | 0.29 | 0.29 |
| 338.80 | 3.09 | 3.09 |
| 331.83 | 3.97 | 3.97 |
| 393.47 | 3.37 | 3.37 |
| 382.22 | 4.64 | 4.64 |
| 282.28 | 2.92 | 2.92 |
| 333.35 | 3.22 | 3.22 |
| 336.35 | 2.87 | 2.87 |
| 285.32 | 1.97 | 1.97 |
| 402.27 | 2.24 | 2.24 |
| 304.33 | 1.52 | 1.52 |
| 375.40 | 4.15 | 4.15 |
| 349.37 | 1.10 | 1.10 |
| 356.39 | 4.13 | 4.13 |
| 311.41 | 2.44 | 2.44 |
| 381.46 | 2.45 | 2.45 |
| 374.23 | 4.07 | 4.07 |
| 358.38 | 2.78 | 2.78 |
| 434.50 | 4.62 | 4.62 |
| 379.85 | 4.16 | 4.16 |
| 479.48 | 1.78 | 1.78 |
| 464.57 | 3.95 | 3.95 |
| 464.54 | 2.82 | 2.82 |
| 464.47 | 2.02 | 2.02 |
| 466.29 | 1.14 | 1.14 |
| 446.88 | 4.39 | 4.39 |
| 339.18 | 4.11 | 4.11 |
| 419.39 | 2.80 | 2.80 |