ID: ALA1794365
Type: Functional
Description: PUBCHEM_BIOASSAY: Viability counterscreen of potential LMP-1 inhibitors in HEK293 cell background Measured in Cell-Based System Using Plate Reader - 2122-02_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504586]
Organism: Homo sapiens
Cell type: HEK293
Bioactivity
Activity Types for Assay ALA1794365
AC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
239.27 | 2.86 | 2.86 |
588.56 | 1.34 | 1.34 |
162.19 | 1.99 | 1.99 |
233.27 | 3.21 | 3.21 |
234.30 | 3.74 | 3.74 |
264.33 | 3.75 | 3.75 |
367.47 | 3.12 | 3.12 |
292.09 | 3.15 | 3.15 |
241.25 | 1.91 | 1.91 |
419.87 | 1.78 | 1.78 |
234.33 | 1.46 | 1.46 |
253.26 | 2.81 | 2.81 |
314.19 | 4.00 | 4.00 |
237.26 | 3.08 | 3.08 |
334.42 | 4.25 | 4.25 |
304.81 | 3.67 | 3.67 |
365.39 | 3.85 | 3.85 |
379.42 | 4.24 | 4.24 |
361.23 | 4.47 | 4.47 |
403.31 | 5.64 | 5.64 |
389.28 | 5.11 | 5.11 |
391.52 | 4.65 | 4.65 |
326.78 | 3.82 | 3.82 |
405.54 | 5.18 | 5.18 |
334.42 | 4.29 | 4.29 |
255.10 | 2.85 | 2.85 |
353.60 | 3.57 | 3.57 |
603.76 | 4.11 | 4.11 |
637.04 | 5.55 | 5.55 |
452.67 | 4.40 | 4.40 |
394.34 | 4.06 | 4.06 |
357.46 | 3.74 | 3.74 |
350.37 | 3.23 | 3.23 |
404.26 | 3.76 | 3.76 |
371.87 | 3.24 | 3.24 |
376.28 | 4.13 | 4.13 |
270.29 | 2.62 | 2.62 |
316.41 | 4.20 | 4.20 |
475.61 | 3.82 | 3.82 |
427.13 | 5.28 | 5.28 |
462.83 | 6.70 | 6.70 |
270.29 | 2.41 | 2.41 |
360.42 | 4.52 | 4.52 |
295.30 | 3.00 | 3.00 |
461.52 | 4.27 | 4.27 |
430.41 | 4.71 | 4.71 |
487.52 | 5.04 | 5.04 |
337.34 | 3.07 | 3.07 |
264.32 | 3.93 | 3.93 |
501.07 | 3.43 | 3.43 |
237.26 | 2.59 | 2.59 |
313.40 | 4.92 | 4.92 |
415.44 | 4.38 | 4.38 |
367.83 | 5.01 | 5.01 |
262.29 | 2.12 | 2.12 |
314.41 | 3.91 | 3.91 |
488.50 | 5.12 | 5.12 |
398.53 | 5.41 | 5.41 |
406.49 | 3.71 | 3.71 |
243.27 | 2.20 | 2.20 |
386.28 | 4.50 | 4.50 |
228.25 | 2.34 | 2.34 |
499.62 | 4.56 | 4.56 |
303.75 | 3.67 | 3.67 |
262.33 | 2.97 | 2.97 |
282.31 | 1.05 | 1.05 |
264.31 | 2.17 | 2.17 |
426.00 | 2.18 | 2.18 |
342.40 | 4.32 | 4.32 |
472.46 | 0.27 | 0.27 |
304.24 | 2.71 | 2.71 |
241.25 | 1.77 | 1.77 |
347.40 | 3.58 | 3.58 |
316.31 | 3.17 | 3.17 |
335.27 | 3.94 | 3.94 |
278.36 | 3.90 | 3.90 |
431.49 | 5.22 | 5.22 |
316.36 | 3.37 | 3.37 |
379.46 | 4.64 | 4.64 |
272.73 | 4.24 | 4.24 |
249.27 | 4.36 | 4.36 |
262.33 | 2.97 | 2.97 |
327.41 | 3.56 | 3.56 |
353.46 | 4.68 | 4.68 |
365.39 | 3.71 | 3.71 |
238.29 | 3.32 | 3.32 |
479.95 | 4.42 | 4.42 |
352.85 | 4.05 | 4.05 |
278.33 | 2.56 | 2.56 |
350.76 | 4.52 | 4.52 |
294.31 | 2.82 | 2.82 |
464.50 | 2.79 | 2.79 |
370.08 | 4.18 | 4.18 |
353.83 | 3.05 | 3.05 |
541.58 | 4.03 | 4.03 |
219.27 | 2.10 | 2.10 |
276.77 | 3.21 | 3.21 |
320.39 | 3.86 | 3.86 |
370.43 | 5.38 | 5.38 |
378.54 | 5.11 | 5.11 |
422.94 | 5.49 | 5.49 |
427.35 | 3.98 | 3.98 |
343.43 | 3.38 | 3.38 |
300.32 | 2.80 | 2.80 |
346.41 | 3.62 | 3.62 |
329.38 | 3.95 | 3.95 |
339.27 | 3.59 | 3.59 |
265.31 | 3.92 | 3.92 |
377.31 | 4.58 | 4.58 |
354.41 | 5.37 | 5.37 |
274.35 | 3.05 | 3.05 |
335.39 | 4.51 | 4.51 |
476.34 | 4.08 | 4.08 |
340.49 | 5.35 | 5.35 |
272.30 | 1.88 | 1.88 |
274.32 | 1.90 | 1.90 |
256.26 | 2.11 | 2.11 |
304.78 | 3.57 | 3.57 |
287.75 | 3.71 | 3.71 |
256.30 | 3.04 | 3.04 |
280.28 | 2.26 | 2.26 |
495.01 | 4.64 | 4.64 |
302.32 | 0.49 | 0.49 |
319.19 | 4.72 | 4.72 |
379.86 | 3.13 | 3.13 |
350.45 | 5.32 | 5.32 |
669.55 | 6.81 | 6.81 |
464.35 | 4.87 | 4.87 |
340.42 | 5.48 | 5.48 |
229.31 | 3.02 | 3.02 |
429.86 | 2.59 | 2.59 |
368.86 | 4.99 | 4.99 |
326.40 | 4.35 | 4.35 |
258.30 | 3.47 | 3.47 |
475.04 | 5.88 | 5.88 |
494.04 | 4.12 | 4.12 |
324.45 | 3.58 | 3.58 |
223.24 | 2.80 | 2.80 |
245.71 | 2.93 | 2.93 |
464.51 | 2.79 | 2.79 |
466.56 | 3.33 | 3.33 |
356.81 | 3.83 | 3.83 |
306.79 | 3.82 | 3.82 |
318.78 | 3.44 | 3.44 |
375.26 | 4.86 | 4.86 |
249.31 | 3.81 | 3.81 |
264.54 | 3.82 | 3.82 |
398.92 | 4.32 | 4.32 |
251.35 | 4.78 | 4.78 |
507.02 | 6.55 | 6.55 |
366.44 | 3.94 | 3.94 |
319.36 | 4.34 | 4.34 |
279.30 | 4.36 | 4.36 |
363.85 | 4.96 | 4.96 |
430.50 | 4.96 | 4.96 |
329.81 | 4.35 | 4.35 |
480.03 | 5.34 | 5.34 |
532.49 | 6.21 | 6.21 |
354.84 | 4.60 | 4.60 |
242.30 | 3.37 | 3.37 |
377.76 | 2.39 | 2.39 |
290.34 | 3.35 | 3.35 |
269.30 | 3.02 | 3.02 |
392.68 | 4.62 | 4.62 |
288.35 | 2.80 | 2.80 |
545.11 | 3.39 | 3.39 |
394.50 | 3.84 | 3.84 |
251.33 | 3.31 | 3.31 |
252.27 | 2.77 | 2.77 |
412.43 | 2.01 | 2.01 |
363.16 | 4.67 | 4.67 |
231.32 | 2.25 | 2.25 |
374.23 | 3.76 | 3.76 |
399.27 | 4.20 | 4.20 |
243.26 | 3.49 | 3.49 |
357.89 | 4.12 | 4.12 |
398.46 | 2.63 | 2.63 |
423.90 | 4.46 | 4.46 |
266.30 | 3.43 | 3.43 |
814.84 | 5.62 | 5.62 |
268.25 | 1.91 | 1.91 |
319.28 | 2.94 | 2.94 |
360.41 | 3.94 | 3.94 |
301.30 | 1.58 | 1.58 |
274.37 | 3.13 | 3.13 |
391.43 | 2.35 | 2.35 |
237.26 | 2.31 | 2.31 |
503.58 | 4.39 | 4.39 |
255.35 | 3.51 | 3.51 |
384.36 | 2.93 | 2.93 |
295.35 | 1.96 | 1.96 |
390.23 | 3.95 | 3.95 |
456.22 | 5.03 | 5.03 |
337.30 | 3.91 | 3.91 |
306.67 | 3.23 | 3.23 |
362.55 | 4.95 | 4.95 |
284.39 | 3.10 | 3.10 |
346.49 | 1.96 | 1.96 |
466.08 | 3.18 | 3.18 |
374.48 | 3.16 | 3.16 |
269.33 | 2.92 | 2.92 |
302.34 | 4.21 | 4.21 |
209.28 | 0.29 | 0.29 |
394.47 | 4.35 | 4.35 |
276.41 | 2.47 | 2.47 |
331.80 | 3.62 | 3.62 |
335.79 | 3.93 | 3.93 |
323.15 | 2.40 | 2.40 |
300.39 | 2.80 | 2.80 |
276.41 | 2.56 | 2.56 |
401.33 | 5.37 | 5.37 |
253.26 | 2.45 | 2.45 |
229.24 | 1.94 | 1.94 |
304.81 | 3.45 | 3.45 |
555.63 | 3.33 | 3.33 |
427.50 | 2.87 | 2.87 |
439.00 | 4.30 | 4.30 |
688.12 | 4.58 | 4.58 |
455.31 | 4.51 | 4.51 |
721.74 | 3.07 | 3.07 |
355.78 | 3.58 | 3.58 |
245.31 | 0.98 | 0.98 |
270.36 | 2.79 | 2.79 |
673.83 | 3.55 | 3.55 |
305.38 | 3.17 | 3.17 |
497.62 | 3.94 | 3.94 |
248.35 | 1.78 | 1.78 |
431.88 | 3.59 | 3.59 |
773.65 | 6.93 | 6.93 |
398.31 | 3.69 | 3.69 |
388.50 | 3.99 | 3.99 |
291.35 | 4.42 | 4.42 |
262.38 | 2.17 | 2.17 |
364.45 | 4.34 | 4.34 |
393.36 | 4.61 | 4.61 |
677.65 | 6.14 | 6.14 |
262.34 | 3.17 | 3.17 |
352.30 | 2.48 | 2.48 |
478.54 | 4.48 | 4.48 |
384.45 | 3.17 | 3.17 |
271.29 | 3.55 | 3.55 |
276.30 | 3.53 | 3.53 |
298.29 | 2.42 | 2.42 |
459.62 | 3.44 | 3.44 |
272.33 | 2.11 | 2.11 |
330.39 | 4.12 | 4.12 |
697.85 | 3.55 | 3.55 |
467.36 | 4.23 | 4.23 |
257.32 | 1.80 | 1.80 |
362.39 | 2.65 | 2.65 |
361.67 | 2.12 | 2.12 |
275.70 | 2.20 | 2.20 |
351.41 | 4.02 | 4.02 |
364.20 | 2.71 | 2.71 |
282.68 | 1.92 | 1.92 |
341.41 | 4.58 | 4.58 |
329.36 | 2.28 | 2.28 |
329.45 | 3.77 | 3.77 |
359.18 | 3.66 | 3.66 |
318.17 | 3.00 | 3.00 |
380.41 | 4.32 | 4.32 |
302.29 | 2.45 | 2.45 |
282.30 | 2.72 | 2.72 |
287.33 | 3.56 | 3.56 |
455.26 | 4.13 | 4.13 |
274.35 | 2.11 | 2.11 |
428.45 | 5.12 | 5.12 |
278.70 | 2.29 | 2.29 |
355.40 | 4.57 | 4.57 |
318.38 | 3.77 | 3.77 |
408.48 | 3.56 | 3.56 |
293.71 | 1.87 | 1.87 |
346.41 | 4.52 | 4.52 |
389.46 | 3.64 | 3.64 |
253.26 | 2.68 | 2.68 |
306.33 | 2.77 | 2.77 |
325.32 | 2.35 | 2.35 |
374.40 | 3.03 | 3.03 |
399.25 | 3.00 | 3.00 |
371.40 | 2.77 | 2.77 |
381.39 | 2.34 | 2.34 |
409.45 | 5.31 | 5.31 |
349.82 | 2.39 | 2.39 |
447.37 | 2.31 | 2.31 |
288.31 | 2.95 | 2.95 |
370.41 | 3.91 | 3.91 |
253.31 | 2.41 | 2.41 |
323.40 | 3.56 | 3.56 |
388.42 | 4.04 | 4.04 |
430.47 | 3.58 | 3.58 |
291.31 | 2.70 | 2.70 |
601.41 | 4.34 | 4.34 |
392.48 | 2.66 | 2.66 |
272.33 | 2.66 | 2.66 |
389.53 | 4.75 | 4.75 |
437.46 | 4.18 | 4.18 |
307.35 | 3.25 | 3.25 |
320.35 | 3.99 | 3.99 |
295.39 | 3.53 | 3.53 |
291.31 | 3.41 | 3.41 |
315.38 | 2.49 | 2.49 |
313.36 | 1.79 | 1.79 |
373.43 | 2.22 | 2.22 |
248.67 | 2.28 | 2.28 |
351.41 | 2.56 | 2.56 |
476.54 | 4.47 | 4.47 |
328.44 | 4.11 | 4.11 |
375.43 | 3.82 | 3.82 |
274.35 | 2.50 | 2.50 |