Basic Information
ID: ALA1794380
Type: Functional
Description: PUBCHEM_BIOASSAY: qHTS for Inhibitors of ATXN expression: Validation of Cytotoxic Assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588378, AID588380]
Organism: Homo sapiens
Cell type: SH-SY5Y
Activity Charts
Bioactivity
Activity Types for Assay ALA1794380
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 317.18 | 4.50 | 4.50 |
| 383.41 | 1.78 | 1.78 |
| 321.16 | 2.20 | 2.20 |
| 280.42 | 3.88 | 3.88 |
| 391.56 | 6.86 | 6.86 |
| 168.15 | 1.22 | 1.22 |
| 314.86 | 4.53 | 4.53 |
| 231.09 | 1.81 | 1.81 |
| 454.61 | 5.09 | 5.09 |
| 407.51 | 4.95 | 4.95 |
| 259.35 | 2.58 | 2.58 |
| 121.14 | 0.79 | 0.79 |
| 328.41 | 2.14 | 2.14 |
| 309.33 | 4.44 | 4.44 |
| 326.83 | 3.72 | 3.72 |
| 263.38 | 3.83 | 3.83 |
| 399.97 | 5.97 | 5.97 |
| 393.47 | 4.51 | 4.51 |
| 394.42 | 3.70 | 3.70 |
| 196.20 | 0.64 | 0.64 |
| 214.22 | 0.73 | 0.73 |
| 284.36 | 2.95 | 2.95 |
| 211.22 | 0.44 | 0.44 |
| 267.33 | 2.85 | 2.85 |
| 335.45 | 5.43 | 5.43 |
| 444.49 | -0.14 | -0.14 |
| 153.18 | 0.60 | 0.60 |
| 287.79 | 3.67 | 3.67 |
| 348.36 | 2.08 | 2.08 |
| 301.33 | 3.03 | 3.03 |
| 370.59 | 5.89 | 5.89 |
| 318.87 | 4.89 | 4.89 |
| 266.39 | 3.53 | 3.53 |
| 1202.63 | ||
| 376.50 | 4.72 | 4.72 |
| 319.88 | 4.81 | 4.81 |
| 329.37 | 3.33 | 3.33 |
| 204.23 | 0.83 | 0.83 |
| 473.59 | 6.08 | 6.08 |
| 371.52 | 6.00 | 6.00 |
| 654.61 | 3.19 | 3.19 |
| 853.92 | 3.74 | 3.74 |
| 319.45 | 3.94 | 3.94 |
| 414.41 | 2.41 | 2.41 |
| 274.80 | 3.82 | 3.82 |
| 332.34 | 3.43 | 3.43 |
| 348.38 | 3.72 | 3.72 |
| 562.67 | 7.50 | 7.50 |
| 238.29 | 3.12 | 3.12 |
| 110.11 | 1.10 | 1.10 |
| 344.85 | 5.38 | 5.38 |
| 394.86 | 5.13 | 5.13 |
| 283.26 | 3.06 | 3.06 |
| 324.42 | 3.17 | 3.17 |
| 242.27 | 2.75 | 2.75 |
| 284.43 | 4.24 | 4.24 |
| 497.60 | 5.03 | 5.03 |
| 403.98 | 3.94 | 3.94 |
| 352.43 | 5.26 | 5.26 |
| 212.17 | 2.89 | 2.89 |
| 253.27 | 0.83 | 0.83 |
| 471.69 | 6.45 | 6.45 |
| 281.36 | 2.84 | 2.84 |
| 171.28 | 1.67 | 1.67 |
| 403.53 | 4.06 | 4.06 |
| 450.57 | 5.32 | 5.32 |
| 277.41 | 4.17 | 4.17 |
| 341.45 | 3.24 | 3.24 |
| 645.32 | 6.94 | 6.94 |
| 284.43 | 4.24 | 4.24 |
| 294.44 | 4.12 | 4.12 |
| 272.39 | 3.61 | 3.61 |
| 277.41 | 4.21 | 4.21 |
| 459.41 | 5.17 | 5.17 |
| 320.43 | 5.17 | 5.17 |
| 382.46 | 2.86 | 2.86 |
| 451.48 | 1.72 | 1.72 |
| 211.22 | 0.44 | 0.44 |
| 110.11 | 1.10 | 1.10 |
| 414.59 | 5.04 | 5.04 |
| 334.35 | 3.26 | 3.26 |
| 406.48 | 3.74 | 3.74 |
| 437.53 | 4.31 | 4.31 |
| 426.52 | 4.60 | 4.60 |
| 373.95 | 4.58 | 4.58 |
| 404.50 | 5.39 | 5.39 |
| 308.38 | 0.53 | 0.53 |
| 550.76 | 5.98 | 5.98 |
| 522.71 | 5.20 | 5.20 |
| 472.09 | 8.01 | 8.01 |
| 542.42 | 4.16 | 4.16 |
| 582.92 | 7.22 | 7.22 |
| 395.47 | 4.23 | 4.23 |
| 167.21 | 0.86 | 0.86 |
| 393.35 | -2.68 | -2.68 |
| 311.38 | 3.34 | 3.34 |
| 247.32 | 2.39 | 2.39 |
| 329.83 | 3.93 | 3.93 |
| 295.38 | 3.27 | 3.27 |
| 516.55 | 5.40 | 5.40 |
| 306.24 | 5.18 | 5.18 |
| 180.21 | 2.78 | 2.78 |
| 582.79 | 6.80 | 6.80 |
| 258.28 | 1.55 | 1.55 |
| 340.49 | 4.83 | 4.83 |
| 329.44 | 3.26 | 3.26 |
| 477.05 | 5.09 | 5.09 |
| 312.80 | 3.38 | 3.38 |
| 338.21 | 4.10 | 4.10 |
| 592.78 | 6.54 | 6.54 |
| 370.46 | 5.59 | 5.59 |
| 428.44 | 2.54 | 2.54 |
| 495.64 | 5.27 | 5.27 |
| 302.41 | 3.62 | 3.62 |
| 274.18 | ||
| 399.62 | 4.23 | 4.23 |
| 480.65 | 4.94 | 4.94 |
| 327.18 | 4.09 | 4.09 |
| 518.56 | 6.38 | 6.38 |
| 484.64 | 5.10 | 5.10 |
| 434.53 | 4.60 | 4.60 |
| 301.39 | 2.96 | 2.96 |
| 308.31 | 2.76 | 2.76 |
| 504.64 | -0.02 | -0.02 |
| 294.31 | 2.32 | 2.32 |
| 308.34 | 2.36 | 2.36 |
| 322.36 | 2.75 | 2.75 |
| 280.28 | 2.64 | 2.64 |
| 418.28 | 3.49 | 3.49 |
| 414.51 | 3.57 | 3.57 |
| 296.55 | 3.62 | 3.62 |
| 291.44 | 4.56 | 4.56 |
| 351.86 | 2.69 | 2.69 |
| 331.80 | 3.33 | 3.33 |
| 344.91 | 4.34 | 4.34 |
| 414.33 | 2.91 | 2.91 |
| 318.24 | 1.69 | 1.69 |
| 448.44 | 1.65 | 1.65 |
| 228.25 | 2.97 | 2.97 |
| 325.45 | 3.77 | 3.77 |
| 244.25 | 2.68 | 2.68 |
| 251.29 | 2.00 | 2.00 |
| 326.44 | 3.52 | 3.52 |
| 283.42 | 3.64 | 3.64 |
| 520.95 | 5.01 | 5.01 |
| 447.36 | 4.83 | 4.83 |
| 333.47 | 3.40 | 3.40 |
| 337.42 | 3.67 | 3.67 |
| 385.51 | 1.20 | 1.20 |
| 282.39 | 4.42 | 4.42 |
| 255.16 | 2.16 | 2.16 |
| 218.30 | 1.76 | 1.76 |
| 381.55 | 5.16 | 5.16 |
| 213.24 | 3.51 | 3.51 |
| 376.39 | 0.53 | 0.53 |
| 302.37 | 3.57 | 3.57 |
| 303.41 | 4.89 | 4.89 |
| 311.47 | 3.96 | 3.96 |
| 650.76 | 3.93 | 3.93 |
| 286.36 | 3.59 | 3.59 |
| 293.37 | 3.41 | 3.41 |
| 356.56 | 4.40 | 4.40 |
| 313.79 | 3.43 | 3.43 |
| 291.38 | 1.22 | 1.22 |
| 497.50 | 1.02 | 1.02 |
| 309.49 | 4.40 | 4.40 |
| 356.51 | 3.25 | 3.25 |
| 284.31 | 2.90 | 2.90 |
| 213.19 | -0.24 | -0.24 |
| 523.74 | 6.49 | 6.49 |
| 299.41 | 3.43 | 3.43 |
| 456.68 | 6.17 | 6.17 |
| 395.26 | 2.63 | 2.63 |
| 345.53 | 3.57 | 3.57 |
| 337.46 | 4.24 | 4.24 |
| 386.45 | 5.28 | 5.28 |
| 220.32 | 2.32 | 2.32 |
| 604.70 | 3.54 | 3.54 |
| 277.28 | 4.42 | 4.42 |
| 256.26 | 2.70 | 2.70 |
| 355.31 | 4.01 | 4.01 |
| 354.46 | 3.20 | 3.20 |
| 191.30 | 1.58 | 1.58 |
| 357.49 | 3.34 | 3.34 |
| 392.50 | 3.41 | 3.41 |
| 292.21 | 4.79 | 4.79 |
| 531.44 | 4.21 | 4.21 |
| 281.36 | 3.15 | 3.15 |
| 425.40 | 4.56 | 4.56 |
| 200.11 | 0.91 | 0.91 |
| 356.18 | 5.18 | 5.18 |
| 385.90 | 3.93 | 3.93 |
| 289.76 | 3.03 | 3.03 |
| 318.39 | 1.06 | 1.06 |
| 573.64 | ||
| 406.50 | 3.21 | 3.21 |
| 363.50 | 3.31 | 3.31 |
| 361.46 | 3.23 | 3.23 |
| 413.43 | 2.88 | 2.88 |
| 357.41 | -1.25 | -1.25 |
| 279.10 | -0.20 | -0.20 |
| 337.42 | 4.41 | 4.41 |
| 305.73 | 1.07 | 1.07 |
| 319.76 | 0.54 | 0.54 |
| 425.92 | 3.35 | 3.35 |
| 478.55 | 5.18 | 5.18 |
| 418.45 | 2.97 | 2.97 |
| 336.29 | 0.75 | 0.75 |
| 584.66 | -1.51 | -1.51 |
| 295.38 | 3.63 | 3.63 |
| 451.68 | 5.28 | 5.28 |
| 327.12 | 3.86 | 3.86 |
| 434.28 | 6.35 | 6.35 |
| 481.68 | 6.23 | 6.23 |
| 191.19 | 1.50 | 1.50 |
| 384.26 | 3.96 | 3.96 |
| 479.53 | 3.68 | 3.68 |
| 310.40 | 1.73 | 1.73 |
| 416.28 | 2.43 | 2.43 |
| 417.63 | 6.79 | 6.79 |
| 244.21 | -3.17 | -3.17 |
| 301.47 | 4.33 | 4.33 |
| 611.74 | 6.48 | 6.48 |
| 346.34 | 2.18 | 2.18 |
| 459.59 | 5.34 | 5.34 |
| 395.54 | 4.55 | 4.55 |
| 241.25 | 1.91 | 1.91 |
| 308.34 | 2.88 | 2.88 |
| 308.34 | 2.88 | 2.88 |
| 218.21 | 1.57 | 1.57 |
| 207.25 | 1.81 | 1.81 |
| 241.25 | 1.51 | 1.51 |
| 249.34 | 2.80 | 2.80 |
| 428.49 | 0.83 | 0.83 |
| 471.56 | 2.88 | 2.88 |
| 492.53 | 4.28 | 4.28 |
| 360.37 | 2.57 | 2.57 |
| 248.32 | 2.76 | 2.76 |
| 343.90 | 5.10 | 5.10 |
| 311.78 | 0.72 | 0.72 |
| 332.85 | 1.58 | 1.58 |
| 220.25 | 1.29 | 1.29 |
| 311.34 | 3.21 | 3.21 |
| 384.31 | 1.45 | 1.45 |
| 176.18 | -2.01 | -2.01 |
| 376.58 | 5.66 | 5.66 |
| 316.47 | 4.18 | 4.18 |
| 183.21 | 0.35 | 0.35 |
| 317.82 | 3.68 | 3.68 |
| 357.16 | ||
| 496.68 | 3.80 | 3.80 |
| 661.80 | 3.82 | 3.82 |
| 490.65 | 3.87 | 3.87 |
| 172.32 | 2.02 | 2.02 |
| 361.53 | 5.53 | 5.53 |
| 193.16 | 1.66 | 1.66 |
| 331.46 | 5.32 | 5.32 |
| 208.26 | 1.16 | 1.16 |
| 401.50 | 4.22 | 4.22 |
| 452.56 | 3.91 | 3.91 |
| 402.44 | 1.90 | 1.90 |
| 603.76 | 4.11 | 4.11 |
| 774.17 | 3.85 | 3.85 |
| 211.26 | 1.13 | 1.13 |
| 309.33 | 4.44 | 4.44 |
| 267.36 | 3.13 | 3.13 |
| 269.34 | 2.72 | 2.72 |
| 322.50 | 4.39 | 4.39 |
| 652.26 | 10.29 | 10.29 |
| 181.22 | 0.28 | 0.28 |
| 237.22 | -1.20 | -1.20 |
| 175.14 | 2.19 | 2.19 |
| 286.40 | 3.70 | 3.70 |
| 555.66 | 4.26 | 4.26 |
| 235.34 | 2.95 | 2.95 |
| 349.57 | ||
| 523.63 | 5.53 | 5.53 |
| 292.46 | 4.55 | 4.55 |
| 290.45 | 4.75 | 4.75 |
| 300.31 | 3.34 | 3.34 |
| 437.19 | 3.21 | 3.21 |
| 429.60 | 5.41 | 5.41 |
| 325.45 | 3.14 | 3.14 |
| 650.78 | 3.28 | 3.28 |
| 522.61 | 2.97 | 2.97 |
| 211.22 | 0.14 | 0.14 |
| 404.43 | 2.96 | 2.96 |
| 287.41 | 2.93 | 2.93 |
| 366.46 | 4.15 | 4.15 |
| 211.20 | 1.35 | 1.35 |
| 327.43 | 5.74 | 5.74 |
| 491.65 | 5.96 | 5.96 |
| 198.23 | 1.87 | 1.87 |
| 324.42 | 3.17 | 3.17 |
| 392.18 | ||
| 287.75 | 4.00 | 4.00 |
| 467.42 | 3.81 | 3.81 |
| 268.23 | 0.97 | 0.97 |
| 392.55 | 5.74 | 5.74 |
| 456.50 | 1.53 | 1.53 |
| 824.97 | 3.52 | 3.52 |
| 481.48 | 3.98 | 3.98 |
| 394.49 | 4.04 | 4.04 |
| 393.28 | 6.20 | 6.20 |
| 810.99 | 3.99 | 3.99 |
| 186.26 | 2.01 | 2.01 |
| 350.47 | 5.16 | 5.16 |
| 385.82 | 3.06 | 3.06 |
| 415.49 | 3.84 | 3.84 |
| 586.68 | -1.44 | -1.44 |
| 250.26 | 1.87 | 1.87 |
| 340.85 | 2.69 | 2.69 |
| 201.22 | 1.64 | 1.64 |
| 343.20 | 1.52 | 1.52 |
| 508.45 | 5.68 | 5.68 |
| 280.36 | 2.11 | 2.11 |
| 249.36 | 2.74 | 2.74 |
| 261.35 | 2.74 | 2.74 |
| 375.17 | -0.39 | -0.39 |
| 466.67 | 5.22 | 5.22 |
| 220.23 | 4.43 | 4.43 |
| 322.45 | 4.00 | 4.00 |
| 392.50 | 2.39 | 2.39 |
| 875.11 | 5.60 | 5.60 |
| 427.67 | 5.01 | 5.01 |