Basic Information
ID: ALA1794387
Type: Functional
Description: PUBCHEM_BIOASSAY: SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2540, AID2575]
Activity Charts
Bioactivity
Activity Types for Assay ALA1794387
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 292.34 | 2.71 | 2.71 |
| 286.72 | 4.11 | 4.11 |
| 308.34 | 3.05 | 3.05 |
| 278.31 | 3.30 | 3.30 |
| 278.72 | 3.80 | 3.80 |
| 210.25 | 1.88 | 1.88 |
| 222.25 | 2.97 | 2.97 |
| 310.40 | 4.76 | 4.76 |
| 298.73 | 4.27 | 4.27 |
| 277.23 | 2.95 | 2.95 |
| 280.33 | 4.02 | 4.02 |
| 321.34 | 3.57 | 3.57 |
| 256.23 | 3.15 | 3.15 |
| 249.27 | 3.30 | 3.30 |
| 333.44 | 2.74 | 2.74 |
| 397.44 | 2.34 | 2.34 |
| 351.38 | 4.67 | 4.67 |
| 273.32 | 2.66 | 2.66 |
| 350.42 | 4.43 | 4.43 |
| 278.35 | 4.15 | 4.15 |
| 280.28 | 3.32 | 3.32 |
| 261.32 | 3.43 | 3.43 |
| 445.34 | 4.74 | 4.74 |
| 272.30 | 4.11 | 4.11 |
| 490.99 | 4.34 | 4.34 |
| 320.35 | 3.31 | 3.31 |
| 320.14 | 3.43 | 3.43 |
| 296.39 | 4.08 | 4.08 |
| 284.27 | 1.77 | 1.77 |
| 414.53 | 5.00 | 5.00 |
| 398.37 | 3.41 | 3.41 |
| 366.47 | 2.74 | 2.74 |
| 408.55 | 3.53 | 3.53 |
| 307.35 | 3.68 | 3.68 |
| 463.36 | 3.82 | 3.82 |
| 278.27 | 0.68 | 0.68 |
| 399.29 | 4.39 | 4.39 |
| 507.64 | 4.41 | 4.41 |
| 354.41 | 3.32 | 3.32 |
| 316.40 | 4.03 | 4.03 |
| 364.43 | 4.58 | 4.58 |
| 322.32 | 2.78 | 2.78 |
| 264.32 | 3.76 | 3.76 |
| 459.37 | 5.13 | 5.13 |
| 268.34 | 4.28 | 4.28 |
| 321.35 | 4.66 | 4.66 |
| 253.33 | 3.95 | 3.95 |
| 289.72 | 3.63 | 3.63 |
| 282.27 | 3.75 | 3.75 |
| 408.94 | 4.89 | 4.89 |
| 252.73 | 3.30 | 3.30 |
| 315.41 | 4.18 | 4.18 |
| 307.35 | 4.11 | 4.11 |
| 308.82 | 4.57 | 4.57 |
| 294.31 | 3.62 | 3.62 |
| 294.79 | 4.26 | 4.26 |
| 340.43 | 5.02 | 5.02 |
| 432.27 | 4.26 | 4.26 |
| 330.84 | 4.73 | 4.73 |
| 416.30 | 5.44 | 5.44 |
| 315.41 | 4.18 | 4.18 |
| 299.28 | 2.45 | 2.45 |
| 295.34 | 3.41 | 3.41 |
| 292.75 | 4.10 | 4.10 |
| 300.75 | 4.50 | 4.50 |
| 436.47 | 5.34 | 5.34 |
| 423.52 | 5.08 | 5.08 |
| 465.54 | 5.29 | 5.29 |
| 397.43 | 3.08 | 3.08 |
| 352.44 | 2.83 | 2.83 |
| 394.29 | 4.70 | 4.70 |
| 264.28 | 3.61 | 3.61 |
| 342.83 | 5.52 | 5.52 |
| 336.37 | 3.19 | 3.19 |
| 401.92 | 5.55 | 5.55 |
| 368.41 | 2.76 | 2.76 |
| 302.26 | 4.32 | 4.32 |
| 478.04 | 5.18 | 5.18 |
| 346.80 | 3.73 | 3.73 |
| 344.87 | 5.60 | 5.60 |
| 261.33 | 3.01 | 3.01 |
| 348.79 | 5.40 | 5.40 |
| 265.27 | 3.83 | 3.83 |
| 445.57 | 4.12 | 4.12 |
| 313.38 | 3.02 | 3.02 |
| 356.76 | 5.22 | 5.22 |
| 429.95 | 5.65 | 5.65 |
| 260.34 | 3.61 | 3.61 |
| 392.55 | 4.68 | 4.68 |
| 316.45 | 4.95 | 4.95 |
| 294.81 | 4.47 | 4.47 |
| 350.90 | 5.61 | 5.61 |
| 316.74 | 3.98 | 3.98 |
| 279.30 | 3.31 | 3.31 |
| 290.37 | 4.86 | 4.86 |
| 337.81 | 5.17 | 5.17 |
| 368.39 | 3.23 | 3.23 |
| 291.76 | 3.54 | 3.54 |
| 449.97 | 5.06 | 5.06 |
| 387.41 | 4.97 | 4.97 |
| 313.43 | 4.23 | 4.23 |
| 266.27 | 4.05 | 4.05 |
| 339.44 | 5.44 | 5.44 |
| 308.29 | 0.69 | 0.69 |
| 307.35 | 4.11 | 4.11 |
| 336.44 | 3.12 | 3.12 |
| 368.44 | 2.53 | 2.53 |
| 278.31 | 3.92 | 3.92 |
| 342.38 | 3.33 | 3.33 |
| 291.29 | 3.92 | 3.92 |
| 720.46 | 8.45 | 8.45 |
| 363.43 | 5.61 | 5.61 |
| 303.29 | 4.63 | 4.63 |
| 249.32 | 3.92 | 3.92 |
| 274.37 | 3.92 | 3.92 |
| 368.35 | 3.08 | 3.08 |
| 366.51 | 6.11 | 6.11 |
| 385.82 | 5.32 | 5.32 |
| 342.78 | 4.58 | 4.58 |
| 359.86 | 5.79 | 5.79 |
| 238.25 | 3.11 | 3.11 |
| 330.84 | 5.36 | 5.36 |
| 327.18 | 4.67 | 4.67 |
| 456.35 | 3.77 | 3.77 |
| 411.46 | 5.10 | 5.10 |
| 297.75 | 4.14 | 4.14 |
| 383.90 | 4.36 | 4.36 |
| 242.23 | 2.06 | 2.06 |
| 294.79 | 4.26 | 4.26 |
| 429.35 | 3.83 | 3.83 |
| 316.47 | 5.16 | 5.16 |
| 426.32 | 3.76 | 3.76 |
| 393.41 | 6.15 | 6.15 |
| 392.17 | 4.65 | 4.65 |
| 260.34 | 3.61 | 3.61 |
| 413.48 | 4.04 | 4.04 |
| 314.77 | 4.89 | 4.89 |
| 330.48 | 5.26 | 5.26 |
| 280.30 | 4.35 | 4.35 |
| 308.82 | 4.57 | 4.57 |
| 269.74 | 4.27 | 4.27 |
| 252.27 | 3.45 | 3.45 |
| 308.36 | 4.60 | 4.60 |
| 408.55 | 3.36 | 3.36 |
| 336.35 | 3.93 | 3.93 |
| 209.27 | 1.28 | 1.28 |
| 342.81 | 5.26 | 5.26 |
| 369.42 | 4.83 | 4.83 |
| 421.88 | 5.53 | 5.53 |
| 466.52 | 3.48 | 3.48 |
| 330.31 | 5.32 | 5.32 |
| 317.44 | 4.35 | 4.35 |
| 343.41 | 5.27 | 5.27 |
| 437.97 | 4.54 | 4.54 |
| 330.48 | 5.26 | 5.26 |
| 536.51 | 5.45 | 5.45 |
| 425.49 | 5.49 | 5.49 |
| 394.38 | 4.00 | 4.00 |
| 471.65 | 5.34 | 5.34 |
| 253.28 | 3.75 | 3.75 |
| 329.23 | 4.92 | 4.92 |
| 294.79 | 4.26 | 4.26 |
| 374.18 | 4.51 | 4.51 |
| 395.35 | 5.72 | 5.72 |
| 310.38 | 4.33 | 4.33 |
| 335.41 | 4.46 | 4.46 |
| 402.28 | 3.56 | 3.56 |
| 314.77 | 4.74 | 4.74 |
| 249.32 | 3.92 | 3.92 |
| 325.42 | 5.14 | 5.14 |
| 487.58 | 3.75 | 3.75 |
| 262.31 | 4.22 | 4.22 |
| 457.45 | 1.23 | 1.23 |
| 295.78 | 3.66 | 3.66 |
| 265.32 | 3.62 | 3.62 |
| 437.33 | 2.90 | 2.90 |
| 379.28 | 5.25 | 5.25 |
| 443.50 | 5.09 | 5.09 |
| 355.44 | 5.14 | 5.14 |
| 382.83 | 3.75 | 3.75 |
| 402.28 | 5.83 | 5.83 |
| 412.49 | 1.23 | 1.23 |
| 422.34 | 5.48 | 5.48 |
| 284.37 | 2.05 | 2.05 |
| 333.34 | 4.46 | 4.46 |
| 384.44 | 1.30 | 1.30 |
| 443.53 | 5.54 | 5.54 |
| 364.47 | 5.95 | 5.95 |
| 375.35 | 2.88 | 2.88 |
| 294.79 | 4.26 | 4.26 |
| 308.82 | 4.57 | 4.57 |
| 391.25 | 4.08 | 4.08 |
| 314.41 | 4.43 | 4.43 |
| 328.78 | 4.95 | 4.95 |
| 308.34 | 3.92 | 3.92 |
| 280.29 | 3.52 | 3.52 |
| 444.00 | 3.62 | 3.62 |
| 476.96 | 4.03 | 4.03 |
| 439.46 | 6.13 | 6.13 |
| 358.89 | 5.99 | 5.99 |
| 359.47 | 4.57 | 4.57 |
| 425.33 | 4.10 | 4.10 |
| 300.36 | 4.25 | 4.25 |
| 431.34 | 3.59 | 3.59 |
| 318.37 | 2.61 | 2.61 |
| 423.52 | 4.66 | 4.66 |
| 299.33 | 4.46 | 4.46 |
| 356.22 | 4.86 | 4.86 |
| 282.30 | 3.20 | 3.20 |
| 334.27 | 5.06 | 5.06 |
| 407.84 | 2.76 | 2.76 |
| 328.80 | 5.13 | 5.13 |
| 312.76 | 4.57 | 4.57 |
| 206.18 | 2.08 | 2.08 |
| 300.38 | 4.48 | 4.48 |
| 276.34 | 4.47 | 4.47 |
| 459.57 | 4.81 | 4.81 |
| 474.55 | 5.64 | 5.64 |
| 440.31 | 3.56 | 3.56 |
| 235.29 | 3.61 | 3.61 |
| 262.31 | 4.22 | 4.22 |
| 441.55 | 6.82 | 6.82 |
| 403.51 | 4.54 | 4.54 |
| 266.27 | 4.05 | 4.05 |
| 352.44 | 2.83 | 2.83 |
| 358.40 | 3.41 | 3.41 |
| 325.80 | 5.14 | 5.14 |
| 333.39 | 3.74 | 3.74 |
| 436.27 | 5.51 | 5.51 |
| 273.30 | 3.78 | 3.78 |
| 382.91 | 3.61 | 3.61 |
| 278.33 | 3.75 | 3.75 |
| 362.48 | 3.79 | 3.79 |
| 316.45 | 4.95 | 4.95 |
| 446.99 | 5.34 | 5.34 |
| 279.25 | 0.08 | 0.08 |
| 288.76 | 4.62 | 4.62 |
| 254.25 | 2.81 | 2.81 |
| 298.73 | 4.27 | 4.27 |
| 352.26 | 5.20 | 5.20 |
| 284.27 | 4.19 | 4.19 |
| 400.44 | 1.01 | 1.01 |
| 388.25 | 3.17 | 3.17 |
| 259.24 | 2.81 | 2.81 |
| 451.98 | 4.67 | 4.67 |
| 386.89 | 3.48 | 3.48 |
| 303.81 | 4.58 | 4.58 |
| 291.29 | 3.92 | 3.92 |
| 370.25 | 5.25 | 5.25 |
| 324.41 | 3.96 | 3.96 |
| 284.27 | 4.19 | 4.19 |
| 266.28 | 4.05 | 4.05 |
| 274.33 | 1.65 | 1.65 |
| 308.34 | 3.92 | 3.92 |
| 294.33 | 4.61 | 4.61 |
| 332.36 | 3.21 | 3.21 |
| 353.45 | 4.53 | 4.53 |
| 452.51 | 3.91 | 3.91 |
| 299.40 | 3.74 | 3.74 |
| 475.98 | 2.90 | 2.90 |
| 318.71 | 4.84 | 4.84 |
| 459.50 | 4.94 | 4.94 |
| 581.16 | 3.84 | 3.84 |
| 311.27 | 3.95 | 3.95 |
| 308.30 | 3.40 | 3.40 |
| 353.38 | 2.89 | 2.89 |