Basic Information
ID: ALA1794410
Type: Functional
Description: PUBCHEM_BIOASSAY: Fluorescence Cell-Based Dose Response to Characterize Compounds Cytotoxic to RAS-Dependent BJ-TERT-LT-ST Fibroblast. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1554, AID1674]
Cell type: BJ
Activity Charts
Bioactivity
Activity Types for Assay ALA1794410
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 248.72 | 2.52 | 2.52 |
| 348.36 | 2.08 | 2.08 |
| 363.37 | 1.66 | 1.66 |
| 266.26 | -1.38 | -1.38 |
| 264.32 | 2.47 | 2.47 |
| 572.66 | 4.37 | 4.37 |
| 285.24 | -1.84 | -1.84 |
| 249.32 | 3.75 | 3.75 |
| 180.21 | 2.78 | 2.78 |
| 339.35 | 2.44 | 2.44 |
| 545.63 | 2.58 | 2.58 |
| 208.22 | 2.73 | 2.73 |
| 223.23 | 2.31 | 2.31 |
| 195.17 | 1.65 | 1.65 |
| 544.53 | 6.81 | 6.81 |
| 337.81 | 4.43 | 4.43 |
| 279.39 | 3.75 | 3.75 |
| 287.10 | 2.77 | 2.77 |
| 265.31 | 0.50 | 0.50 |
| 199.22 | 1.28 | 1.28 |
| 301.35 | 2.60 | 2.60 |
| 360.41 | 1.10 | 1.10 |
| 152.18 | 0.64 | 0.64 |
| 458.50 | 1.98 | 1.98 |
| 302.36 | 3.85 | 3.85 |
| 288.33 | 3.46 | 3.46 |
| 299.33 | 4.47 | 4.47 |
| 277.27 | 1.15 | 1.15 |
| 284.34 | 3.04 | 3.04 |
| 614.56 | 7.32 | 7.32 |
| 457.91 | 1.85 | 1.85 |
| 579.99 | 0.00 | 0.00 |
| 517.11 | 4.94 | 4.94 |
| 352.91 | 3.97 | 3.97 |
| 506.48 | 6.09 | 6.09 |
| 232.32 | 2.77 | 2.77 |
| 322.39 | 4.22 | 4.22 |
| 268.35 | 3.65 | 3.65 |
| 442.60 | 2.97 | 2.97 |
| 331.42 | 4.35 | 4.35 |
| 253.74 | 0.87 | 0.87 |
| 231.30 | 1.42 | 1.42 |
| 306.32 | 1.89 | 1.89 |
| 780.95 | 2.22 | 2.22 |
| 338.12 | 4.01 | 4.01 |
| 362.90 | 5.04 | 5.04 |
| 283.76 | 0.88 | 0.88 |
| 290.37 | 3.94 | 3.94 |
| 501.12 | 7.91 | 7.91 |
| 610.73 | 7.85 | 7.85 |
| 476.54 | 6.83 | 6.83 |
| 414.72 | 3.97 | 3.97 |
| 361.28 | 4.44 | 4.44 |
| 255.10 | 2.85 | 2.85 |
| 641.16 | 4.09 | 4.09 |
| 481.54 | 4.88 | 4.88 |
| 533.96 | 1.02 | 1.02 |
| 579.99 | 0.00 | 0.00 |
| 276.34 | 3.70 | 3.70 |
| 380.78 | 5.10 | 5.10 |
| 297.36 | 2.61 | 2.61 |
| 487.94 | 4.50 | 4.50 |
| 536.76 | 5.99 | 5.99 |
| 414.49 | 2.52 | 2.52 |
| 400.83 | 4.27 | 4.27 |
| 333.39 | 3.54 | 3.54 |
| 360.34 | 5.51 | 5.51 |
| 481.56 | 5.88 | 5.88 |
| 442.97 | 4.43 | 4.43 |
| 445.97 | 3.64 | 3.64 |
| 306.67 | 3.23 | 3.23 |
| 414.37 | 3.56 | 3.56 |
| 528.00 | 7.28 | 7.28 |
| 336.34 | 3.09 | 3.09 |
| 480.56 | 3.63 | 3.63 |
| 533.15 | 5.56 | 5.56 |
| 249.27 | 4.36 | 4.36 |
| 399.49 | 4.15 | 4.15 |
| 631.22 | 4.66 | 4.66 |
| 530.50 | 6.60 | 6.60 |
| 588.90 | 5.20 | 5.20 |
| 488.71 | 4.43 | 4.43 |
| 408.72 | 5.26 | 5.26 |
| 396.94 | 3.18 | 3.18 |
| 298.37 | 3.34 | 3.34 |
| 511.52 | 5.99 | 5.99 |
| 248.20 | 2.23 | 2.23 |
| 461.48 | 4.53 | 4.53 |
| 447.63 | 2.68 | 2.68 |
| 356.81 | 4.21 | 4.21 |
| 277.66 | 3.60 | 3.60 |
| 304.39 | 4.78 | 4.78 |
| 374.89 | 5.11 | 5.11 |
| 339.39 | 3.72 | 3.72 |
| 432.52 | 3.33 | 3.33 |
| 525.66 | 6.02 | 6.02 |
| 343.34 | 4.02 | 4.02 |
| 376.50 | 5.46 | 5.46 |
| 336.44 | 2.56 | 2.56 |
| 343.38 | 3.91 | 3.91 |
| 340.39 | 5.86 | 5.86 |
| 304.29 | 1.92 | 1.92 |
| 336.35 | 2.81 | 2.81 |
| 214.22 | 1.79 | 1.79 |
| 349.43 | 4.41 | 4.41 |
| 447.40 | 6.42 | 6.42 |
| 449.38 | 5.11 | 5.11 |
| 486.57 | 2.92 | 2.92 |
| 376.48 | 5.51 | 5.51 |
| 288.33 | 3.62 | 3.62 |
| 318.83 | 3.97 | 3.97 |
| 348.25 | 5.65 | 5.65 |
| 262.29 | 2.12 | 2.12 |
| 366.45 | 3.71 | 3.71 |
| 527.02 | 7.03 | 7.03 |
| 283.35 | 3.50 | 3.50 |
| 368.46 | 4.64 | 4.64 |
| 272.26 | 2.80 | 2.80 |
| 294.30 | -0.33 | -0.33 |
| 309.39 | 4.35 | 4.35 |
| 241.68 | 3.32 | 3.32 |
| 489.62 | 3.24 | 3.24 |
| 393.19 | 4.26 | 4.26 |
| 410.54 | 4.04 | 4.04 |
| 464.50 | 5.43 | 5.43 |
| 334.80 | 2.57 | 2.57 |
| 291.35 | 2.46 | 2.46 |
| 417.51 | 3.61 | 3.61 |
| 344.84 | 3.70 | 3.70 |
| 316.34 | 3.51 | 3.51 |
| 313.81 | 4.99 | 4.99 |
| 368.46 | 4.64 | 4.64 |
| 271.27 | 3.65 | 3.65 |
| 383.84 | 3.06 | 3.06 |
| 472.41 | 6.14 | 6.14 |
| 375.43 | 3.34 | 3.34 |
| 331.44 | 4.17 | 4.17 |
| 438.55 | 3.87 | 3.87 |
| 341.41 | 3.43 | 3.43 |
| 265.31 | 3.12 | 3.12 |
| 498.61 | 4.41 | 4.41 |
| 249.71 | 2.24 | 2.24 |
| 388.45 | 3.49 | 3.49 |
| 291.33 | 2.22 | 2.22 |
| 255.25 | 2.95 | 2.95 |
| 396.45 | 2.39 | 2.39 |
| 472.46 | 0.27 | 0.27 |
| 336.83 | 3.69 | 3.69 |
| 285.74 | 3.09 | 3.09 |
| 449.33 | 2.87 | 2.87 |
| 337.33 | 3.44 | 3.44 |
| 443.25 | 3.65 | 3.65 |
| 291.65 | 2.92 | 2.92 |
| 428.44 | 5.55 | 5.55 |
| 728.80 | 6.10 | 6.10 |
| 283.28 | 2.55 | 2.55 |
| 304.24 | 2.71 | 2.71 |
| 406.42 | 2.77 | 2.77 |
| 406.40 | 2.94 | 2.94 |
| 267.24 | 2.53 | 2.53 |
| 413.95 | 4.46 | 4.46 |
| 407.90 | 2.99 | 2.99 |
| 352.87 | 4.73 | 4.73 |
| 356.38 | 3.79 | 3.79 |
| 390.08 | 5.34 | 5.34 |
| 311.22 | 3.43 | 3.43 |
| 256.22 | 3.50 | 3.50 |
| 391.41 | 1.80 | 1.80 |
| 442.71 | 4.32 | 4.32 |
| 471.58 | 3.21 | 3.21 |
| 295.73 | 1.95 | 1.95 |
| 356.38 | 3.06 | 3.06 |
| 368.46 | 4.64 | 4.64 |
| 512.50 | 3.27 | 3.27 |
| 312.37 | 3.01 | 3.01 |
| 335.43 | 4.71 | 4.71 |
| 399.60 | 4.87 | 4.87 |
| 377.49 | 4.40 | 4.40 |
| 335.40 | 3.36 | 3.36 |
| 353.81 | 3.42 | 3.42 |
| 305.33 | 4.72 | 4.72 |
| 407.50 | 1.21 | 1.21 |
| 463.58 | 2.95 | 2.95 |
| 222.67 | 3.13 | 3.13 |
| 569.58 | 5.73 | 5.73 |
| 263.30 | 4.66 | 4.66 |
| 285.74 | 3.09 | 3.09 |
| 404.54 | 2.37 | 2.37 |
| 354.84 | 4.25 | 4.25 |
| 396.45 | 2.97 | 2.97 |
| 397.53 | 3.87 | 3.87 |
| 314.37 | 3.57 | 3.57 |
| 440.55 | 4.76 | 4.76 |
| 297.27 | 2.61 | 2.61 |
| 380.78 | 5.10 | 5.10 |
| 376.37 | 3.17 | 3.17 |
| 276.77 | 3.21 | 3.21 |
| 432.01 | 3.97 | 3.97 |
| 466.59 | 4.11 | 4.11 |
| 428.96 | 4.77 | 4.77 |
| 219.26 | 3.02 | 3.02 |
| 384.46 | 4.34 | 4.34 |
| 437.64 | 4.88 | 4.88 |
| 456.89 | 0.98 | 0.98 |
| 263.73 | 2.55 | 2.55 |
| 420.49 | 4.92 | 4.92 |
| 289.36 | 3.08 | 3.08 |
| 405.45 | 3.91 | 3.91 |
| 383.36 | 4.41 | 4.41 |
| 392.46 | 3.38 | 3.38 |
| 310.27 | 3.44 | 3.44 |
| 375.34 | 3.76 | 3.76 |
| 391.38 | 3.45 | 3.45 |
| 441.54 | 3.34 | 3.34 |
| 267.29 | 2.82 | 2.82 |
| 395.46 | 3.49 | 3.49 |
| 318.03 | 6.02 | 6.02 |
| 329.38 | 3.95 | 3.95 |
| 376.37 | 3.17 | 3.17 |
| 222.67 | 3.15 | 3.15 |
| 254.29 | 2.30 | 2.30 |
| 299.36 | 2.81 | 2.81 |
| 339.27 | 3.59 | 3.59 |
| 321.34 | 2.73 | 2.73 |
| 279.73 | 2.33 | 2.33 |
| 246.27 | 4.04 | 4.04 |
| 410.56 | 4.31 | 4.31 |
| 422.53 | 6.09 | 6.09 |
| 359.81 | 3.75 | 3.75 |
| 408.45 | 4.51 | 4.51 |
| 442.97 | 4.43 | 4.43 |
| 288.76 | 4.00 | 4.00 |
| 294.35 | 3.48 | 3.48 |
| 311.78 | 3.66 | 3.66 |
| 410.27 | 4.03 | 4.03 |
| 395.43 | 5.09 | 5.09 |
| 343.38 | 3.53 | 3.53 |
| 441.63 | 5.40 | 5.40 |
| 324.39 | 2.36 | 2.36 |
| 335.36 | 2.39 | 2.39 |
| 459.97 | 4.27 | 4.27 |
| 341.32 | 2.45 | 2.45 |
| 406.23 | 3.16 | 3.16 |
| 471.03 | 4.72 | 4.72 |
| 537.39 | 4.22 | 4.22 |
| 344.23 | 4.93 | 4.93 |
| 403.89 | 3.98 | 3.98 |
| 412.53 | 3.79 | 3.79 |
| 555.64 | 4.91 | 4.91 |
| 173.17 | 1.75 | 1.75 |
| 401.47 | 3.71 | 3.71 |
| 468.44 | 3.20 | 3.20 |
| 465.77 | 5.94 | 5.94 |
| 263.73 | 2.55 | 2.55 |
| 400.27 | 5.20 | 5.20 |
| 498.79 | 5.52 | 5.52 |
| 284.31 | 4.40 | 4.40 |
| 477.41 | 5.08 | 5.08 |
| 409.49 | 3.86 | 3.86 |
| 367.71 | 2.24 | 2.24 |
| 490.54 | 3.74 | 3.74 |
| 464.35 | 4.87 | 4.87 |
| 296.37 | 3.55 | 3.55 |
| 324.38 | 4.06 | 4.06 |
| 313.38 | 3.55 | 3.55 |
| 297.79 | 4.66 | 4.66 |
| 466.59 | 4.17 | 4.17 |
| 217.19 | 2.73 | 2.73 |
| 417.47 | 2.81 | 2.81 |
| 420.92 | 4.52 | 4.52 |
| 485.02 | 6.34 | 6.34 |
| 287.34 | 2.16 | 2.16 |
| 277.27 | 1.10 | 1.10 |
| 281.32 | 3.43 | 3.43 |
| 256.33 | 3.29 | 3.29 |
| 376.21 | 3.32 | 3.32 |
| 358.44 | 4.38 | 4.38 |
| 390.53 | 2.84 | 2.84 |
| 315.38 | 3.65 | 3.65 |
| 406.51 | 1.50 | 1.50 |
| 298.37 | 3.74 | 3.74 |
| 249.71 | 2.24 | 2.24 |
| 445.94 | 3.88 | 3.88 |
| 309.42 | 4.37 | 4.37 |
| 309.41 | 2.97 | 2.97 |
| 546.63 | 3.73 | 3.73 |
| 373.82 | 1.84 | 1.84 |
| 430.56 | 2.69 | 2.69 |
| 296.28 | 1.16 | 1.16 |
| 466.54 | 4.35 | 4.35 |
| 275.26 | 2.50 | 2.50 |
| 366.87 | 4.81 | 4.81 |
| 415.88 | 4.57 | 4.57 |
| 248.28 | 1.00 | 1.00 |
| 386.41 | 3.98 | 3.98 |
| 342.35 | 2.67 | 2.67 |
| 279.30 | 4.36 | 4.36 |
| 341.48 | 4.69 | 4.69 |
| 343.35 | 4.89 | 4.89 |
| 457.53 | 4.67 | 4.67 |
| 386.44 | 3.58 | 3.58 |
| 458.56 | 3.00 | 3.00 |
| 297.27 | 2.91 | 2.91 |
| 322.37 | 3.58 | 3.58 |
| 456.59 | 3.70 | 3.70 |
| 334.41 | 3.37 | 3.37 |
| 460.32 | 3.97 | 3.97 |
| 342.38 | 2.43 | 2.43 |
| 277.33 | 2.67 | 2.67 |
| 319.25 | 1.80 | 1.80 |
| 468.55 | 5.20 | 5.20 |
| 359.39 | 3.85 | 3.85 |
| 592.64 | 3.00 | 3.00 |
| 439.88 | 4.92 | 4.92 |
| 337.38 | 4.14 | 4.14 |
| 380.85 | 3.23 | 3.23 |
| 259.31 | 4.13 | 4.13 |
| 405.43 | 3.12 | 3.12 |
| 276.22 | 2.98 | 2.98 |
| 656.66 | 2.75 | 2.75 |
| 302.36 | 2.22 | 2.22 |
| 287.75 | 3.06 | 3.06 |
| 416.34 | 3.68 | 3.68 |
| 434.50 | 4.25 | 4.25 |
| 394.50 | 3.84 | 3.84 |
| 269.74 | 3.88 | 3.88 |
| 350.03 | 4.63 | 4.63 |
| 281.83 | 4.54 | 4.54 |
| 387.48 | 4.56 | 4.56 |
| 586.68 | -1.44 | -1.44 |
| 316.39 | 2.95 | 2.95 |
| 447.63 | 2.68 | 2.68 |
| 395.85 | 3.68 | 3.68 |
| 540.73 | 5.04 | 5.04 |
| 406.44 | 3.44 | 3.44 |
| 390.53 | 2.74 | 2.74 |
| 452.39 | 5.94 | 5.94 |
| 272.30 | 3.36 | 3.36 |
| 421.01 | 4.00 | 4.00 |
| 421.67 | 4.97 | 4.97 |
| 368.46 | 4.64 | 4.64 |
| 498.47 | 2.88 | 2.88 |
| 496.05 | 6.28 | 6.28 |
| 372.93 | 4.23 | 4.23 |
| 414.53 | 4.43 | 4.43 |
| 367.39 | 3.02 | 3.02 |
| 552.05 | 4.71 | 4.71 |
| 322.41 | 4.42 | 4.42 |
| 455.30 | 5.83 | 5.83 |
| 406.42 | 1.96 | 1.96 |
| 410.49 | 2.19 | 2.19 |
| 354.49 | 5.61 | 5.61 |
| 526.41 | 2.24 | 2.24 |
| 474.57 | 5.58 | 5.58 |
| 585.32 | 4.93 | 4.93 |
| 306.67 | 3.23 | 3.23 |
| 342.20 | 3.25 | 3.25 |
| 292.72 | 3.10 | 3.10 |
| 262.27 | 2.26 | 2.26 |
| 504.57 | 4.92 | 4.92 |
| 320.75 | 1.22 | 1.22 |
| 305.83 | 3.69 | 3.69 |
| 344.33 | 2.69 | 2.69 |
| 418.49 | 4.87 | 4.87 |
| 264.67 | 1.99 | 1.99 |
| 367.29 | 3.29 | 3.29 |
| 489.00 | 5.20 | 5.20 |
| 459.63 | 3.57 | 3.57 |
| 305.38 | 4.31 | 4.31 |
| 249.28 | 2.47 | 2.47 |
| 281.15 | 3.62 | 3.62 |
| 303.34 | 2.07 | 2.07 |
| 304.35 | 4.02 | 4.02 |
| 351.41 | 2.88 | 2.88 |
| 299.33 | 2.25 | 2.25 |
| 237.27 | 2.40 | 2.40 |
| 443.30 | 2.90 | 2.90 |
| 437.52 | 3.48 | 3.48 |
| 356.39 | 3.96 | 3.96 |
| 378.40 | 4.18 | 4.18 |
| 272.26 | 2.08 | 2.08 |
| 306.39 | 3.56 | 3.56 |
| 401.50 | 2.96 | 2.96 |
| 452.74 | 6.01 | 6.01 |
| 299.24 | 2.70 | 2.70 |
| 297.39 | 3.54 | 3.54 |
| 293.71 | 1.87 | 1.87 |
| 361.24 | 3.68 | 3.68 |
| 306.33 | 2.77 | 2.77 |
| 289.34 | 3.39 | 3.39 |
| 448.32 | 5.37 | 5.37 |
| 331.38 | 3.41 | 3.41 |
| 371.40 | 2.77 | 2.77 |
| 361.41 | 3.50 | 3.50 |
| 298.37 | 3.46 | 3.46 |
| 251.29 | 2.79 | 2.79 |
| 434.47 | 3.77 | 3.77 |
| 323.40 | 3.56 | 3.56 |
| 301.20 | 2.92 | 2.92 |
| 362.39 | 4.06 | 4.06 |
| 399.24 | 4.00 | 4.00 |
| 253.27 | 1.36 | 1.36 |
| 340.43 | 4.74 | 4.74 |
| 497.40 | 4.42 | 4.42 |
| 318.25 | 1.79 | 1.79 |
| 331.38 | 3.27 | 3.27 |
| 293.33 | 2.97 | 2.97 |
| 282.35 | 2.36 | 2.36 |
| 275.70 | 3.69 | 3.69 |
| 291.33 | 2.22 | 2.22 |
| 257.27 | 2.37 | 2.37 |
| 309.34 | 4.14 | 4.14 |
| 216.20 | 0.42 | 0.42 |
| 351.41 | 2.56 | 2.56 |
| 277.30 | 1.83 | 1.83 |
| 434.50 | 4.62 | 4.62 |
| 257.27 | 2.37 | 2.37 |
| 427.47 | 1.67 | 1.67 |
| 358.43 | 4.12 | 4.12 |
| 319.34 | 3.40 | 3.40 |
| 287.33 | 3.56 | 3.56 |
| 381.23 | 1.56 | 1.56 |
| 328.44 | 4.11 | 4.11 |