Basic Information
ID: ALA1794425
Type: Functional
Description: PUBCHEM_BIOASSAY: Counterscreen for activators of the GAA850 frataxin promoter: luminescence-based cell-based high throughput dose response assay to identify activators of the GAA30 frataxin promoter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540364, AID588328, AID588350, AID588351]
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1794425
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 276.34 | 4.49 | 4.49 |
| 327.34 | 2.30 | 2.30 |
| 262.19 | -2.71 | -2.71 |
| 453.29 | 3.36 | 3.36 |
| 371.22 | 4.05 | 4.05 |
| 194.24 | 2.97 | 2.97 |
| 328.17 | 3.67 | 3.67 |
| 380.35 | 3.63 | 3.63 |
| 168.17 | 1.56 | 1.56 |
| 317.28 | 3.80 | 3.80 |
| 277.32 | 4.12 | 4.12 |
| 304.81 | 3.67 | 3.67 |
| 266.77 | 3.24 | 3.24 |
| 444.54 | 5.86 | 5.86 |
| 220.28 | 2.93 | 2.93 |
| 490.38 | 4.62 | 4.62 |
| 477.42 | 5.18 | 5.18 |
| 410.50 | 4.15 | 4.15 |
| 545.93 | 5.49 | 5.49 |
| 385.45 | 4.67 | 4.67 |
| 465.58 | 4.21 | 4.21 |
| 516.66 | 4.48 | 4.48 |
| 519.62 | 4.51 | 4.51 |
| 403.37 | 2.41 | 2.41 |
| 388.39 | 4.50 | 4.50 |
| 505.62 | 4.84 | 4.84 |
| 477.33 | 1.22 | 1.22 |
| 360.46 | 3.56 | 3.56 |
| 277.66 | 3.60 | 3.60 |
| 290.37 | 3.73 | 3.73 |
| 621.76 | ||
| 230.70 | 2.97 | 2.97 |
| 390.48 | 5.61 | 5.61 |
| 350.37 | 3.63 | 3.63 |
| 470.05 | 5.85 | 5.85 |
| 417.29 | 4.59 | 4.59 |
| 397.23 | 4.83 | 4.83 |
| 368.39 | 2.77 | 2.77 |
| 451.55 | 3.90 | 3.90 |
| 385.92 | 4.64 | 4.64 |
| 459.61 | 4.10 | 4.10 |
| 408.53 | 5.42 | 5.42 |
| 407.99 | 4.75 | 4.75 |
| 344.44 | 3.92 | 3.92 |
| 487.01 | 5.43 | 5.43 |
| 394.47 | 4.11 | 4.11 |
| 252.24 | 4.03 | 4.03 |
| 365.50 | 3.76 | 3.76 |
| 252.32 | 3.18 | 3.18 |
| 553.71 | 5.31 | 5.31 |
| 435.60 | 5.57 | 5.57 |
| 425.32 | 5.65 | 5.65 |
| 455.51 | 4.59 | 4.59 |
| 322.32 | 2.81 | 2.81 |
| 311.17 | 3.00 | 3.00 |
| 235.29 | 3.08 | 3.08 |
| 344.44 | 3.92 | 3.92 |
| 350.33 | 3.26 | 3.26 |
| 416.59 | 3.10 | 3.10 |
| 345.36 | 5.05 | 5.05 |
| 322.32 | 2.50 | 2.50 |
| 353.92 | 4.33 | 4.33 |
| 432.50 | 1.43 | 1.43 |
| 329.49 | 5.03 | 5.03 |
| 447.34 | 2.53 | 2.53 |
| 438.62 | 5.18 | 5.18 |
| 401.88 | 3.03 | 3.03 |
| 326.19 | 3.02 | 3.02 |
| 427.57 | 2.96 | 2.96 |
| 484.56 | 4.40 | 4.40 |
| 321.38 | 4.52 | 4.52 |
| 372.39 | 5.38 | 5.38 |
| 449.53 | 3.08 | 3.08 |
| 440.89 | 4.46 | 4.46 |
| 382.45 | 3.13 | 3.13 |
| 378.97 | 5.23 | 5.23 |
| 525.68 | 2.63 | 2.63 |
| 321.38 | 4.52 | 4.52 |
| 450.56 | 3.82 | 3.82 |
| 461.63 | 5.53 | 5.53 |
| 376.51 | 4.46 | 4.46 |
| 340.76 | 2.20 | 2.20 |
| 365.28 | 3.08 | 3.08 |
| 378.50 | 3.67 | 3.67 |
| 465.60 | 2.95 | 2.95 |
| 261.35 | 4.19 | 4.19 |
| 328.38 | 3.43 | 3.43 |
| 366.51 | 3.07 | 3.07 |
| 237.31 | 3.29 | 3.29 |
| 420.85 | 3.54 | 3.54 |
| 463.72 | 5.60 | 5.60 |
| 490.63 | 4.28 | 4.28 |
| 363.34 | 3.43 | 3.43 |
| 352.35 | 2.12 | 2.12 |
| 309.33 | 1.69 | 1.69 |
| 447.59 | 5.11 | 5.11 |
| 247.25 | 2.31 | 2.31 |
| 373.43 | 1.82 | 1.82 |
| 388.25 | 3.92 | 3.92 |
| 397.54 | 4.30 | 4.30 |
| 342.14 | 1.92 | 1.92 |
| 372.17 | 3.40 | 3.40 |
| 262.70 | 2.68 | 2.68 |
| 425.56 | 3.17 | 3.17 |
| 376.41 | 3.50 | 3.50 |
| 267.35 | 4.48 | 4.48 |
| 387.48 | 2.95 | 2.95 |
| 344.93 | 4.80 | 4.80 |
| 535.53 | 4.95 | 4.95 |
| 501.01 | 3.34 | 3.34 |
| 383.49 | 4.01 | 4.01 |
| 269.31 | 1.80 | 1.80 |
| 456.98 | 5.59 | 5.59 |
| 322.16 | 2.37 | 2.37 |
| 297.36 | 4.55 | 4.55 |
| 364.27 | 2.85 | 2.85 |
| 410.51 | 1.52 | 1.52 |
| 384.55 | 4.73 | 4.73 |
| 365.46 | 2.57 | 2.57 |
| 297.39 | 3.07 | 3.07 |
| 406.53 | 3.71 | 3.71 |
| 365.39 | 2.46 | 2.46 |
| 342.40 | 4.54 | 4.54 |
| 452.45 | 2.10 | 2.10 |
| 431.18 | 2.20 | 2.20 |
| 241.29 | 2.99 | 2.99 |
| 214.57 | 1.37 | 1.37 |
| 315.74 | 3.16 | 3.16 |
| 396.47 | 3.77 | 3.77 |
| 454.45 | 3.47 | 3.47 |
| 305.31 | 3.93 | 3.93 |
| 391.52 | 5.44 | 5.44 |
| 481.36 | 2.24 | 2.24 |
| 291.36 | 3.54 | 3.54 |
| 311.30 | 2.97 | 2.97 |
| 420.42 | 4.65 | 4.65 |
| 340.51 | 3.73 | 3.73 |
| 302.36 | 3.93 | 3.93 |
| 463.94 | 3.03 | 3.03 |
| 415.90 | 3.97 | 3.97 |
| 277.75 | 3.52 | 3.52 |
| 402.50 | 4.21 | 4.21 |
| 312.76 | 3.43 | 3.43 |
| 487.55 | 4.17 | 4.17 |
| 358.47 | 3.70 | 3.70 |
| 432.48 | 4.47 | 4.47 |
| 421.35 | 5.13 | 5.13 |
| 340.15 | 2.51 | 2.51 |
| 457.36 | 5.52 | 5.52 |
| 390.44 | 3.89 | 3.89 |
| 495.68 | 6.76 | 6.76 |
| 406.49 | 5.08 | 5.08 |
| 527.65 | 5.32 | 5.32 |
| 364.86 | 2.78 | 2.78 |
| 294.36 | 2.99 | 2.99 |
| 357.44 | 2.02 | 2.02 |
| 517.67 | 3.73 | 3.73 |
| 325.37 | 3.51 | 3.51 |
| 665.38 | 6.12 | 6.12 |
| 584.90 | 5.71 | 5.71 |
| 356.45 | 2.45 | 2.45 |
| 408.48 | 5.89 | 5.89 |
| 375.52 | 4.76 | 4.76 |
| 532.54 | 5.31 | 5.31 |
| 438.51 | 3.63 | 3.63 |
| 374.47 | 3.93 | 3.93 |
| 418.56 | 3.27 | 3.27 |
| 341.44 | 3.98 | 3.98 |
| 378.89 | 3.17 | 3.17 |
| 585.32 | 4.93 | 4.93 |
| 384.42 | 4.12 | 4.12 |
| 649.64 | 2.88 | 2.88 |
| 364.28 | 3.33 | 3.33 |
| 430.46 | 3.53 | 3.53 |
| 452.51 | 3.13 | 3.13 |
| 328.51 | 2.53 | 2.53 |
| 657.66 | 1.80 | 1.80 |
| 364.40 | 3.13 | 3.13 |
| 358.83 | 2.12 | 2.12 |
| 348.81 | 2.21 | 2.21 |
| 586.49 | 5.35 | 5.35 |
| 496.61 | 4.63 | 4.63 |
| 425.58 | 3.50 | 3.50 |
| 298.44 | 2.61 | 2.61 |
| 641.67 | 2.10 | 2.10 |
| 165.24 | 0.16 | 0.16 |
| 709.89 | 5.10 | 5.10 |
| 359.86 | 2.69 | 2.69 |
| 520.65 | 3.39 | 3.39 |
| 491.59 | 4.69 | 4.69 |
| 327.53 | 3.14 | 3.14 |
| 279.28 | 1.78 | 1.78 |
| 311.29 | 3.42 | 3.42 |
| 621.13 | 4.02 | 4.02 |
| 390.87 | 2.09 | 2.09 |
| 284.41 | 2.22 | 2.22 |
| 456.64 | 3.39 | 3.39 |
| 395.86 | 5.61 | 5.61 |
| 278.25 | 2.44 | 2.44 |
| 463.00 | 4.41 | 4.41 |
| 225.25 | 2.68 | 2.68 |
| 465.94 | 3.94 | 3.94 |
| 299.17 | 3.70 | 3.70 |
| 467.51 | 4.16 | 4.16 |
| 444.56 | 6.21 | 6.21 |
| 317.49 | 2.73 | 2.73 |
| 368.44 | 4.69 | 4.69 |
| 415.49 | 5.03 | 5.03 |
| 416.83 | 5.87 | 5.87 |
| 156.14 | -1.38 | -1.38 |
| 373.33 | 2.17 | 2.17 |
| 589.76 | 4.83 | 4.83 |
| 417.58 | 3.51 | 3.51 |
| 257.36 | 3.19 | 3.19 |
| 610.18 | 5.18 | 5.18 |
| 254.72 | 3.59 | 3.59 |
| 324.38 | 2.54 | 2.54 |
| 512.55 | 4.66 | 4.66 |
| 460.48 | 2.22 | 2.22 |
| 406.41 | 5.70 | 5.70 |
| 498.53 | 6.84 | 6.84 |
| 223.18 | -1.20 | -1.20 |
| 410.51 | 2.99 | 2.99 |
| 427.93 | 6.07 | 6.07 |
| 453.56 | 3.82 | 3.82 |
| 340.45 | 3.92 | 3.92 |
| 372.88 | 4.68 | 4.68 |
| 458.59 | 5.63 | 5.63 |
| 414.44 | 2.75 | 2.75 |
| 414.82 | 4.56 | 4.56 |
| 424.45 | 3.30 | 3.30 |
| 451.35 | 4.89 | 4.89 |
| 361.24 | 3.68 | 3.68 |
| 322.39 | 2.87 | 2.87 |
| 528.65 | 3.83 | 3.83 |
| 385.22 | 3.82 | 3.82 |
| 327.30 | 1.57 | 1.57 |
| 430.47 | 3.58 | 3.58 |
| 430.47 | 3.58 | 3.58 |
| 448.48 | 3.35 | 3.35 |
| 284.28 | 2.06 | 2.06 |