Basic Information
ID: ALA1794429
Type: Functional
Description: PUBCHEM_BIOASSAY: SAR Analysis of small molecule inhibitors of T-cell specific antigen receptor-induced NF-kB activation in a HEK-293T cell line using a luminescence assay - Set 2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID435003, AID435012, AID489026]
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1794429
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 330.34 | 2.19 | 2.19 |
| 402.54 | 5.85 | 5.85 |
| 374.48 | 5.03 | 5.03 |
| 362.47 | 5.07 | 5.07 |
| 334.42 | 4.25 | 4.25 |
| 334.42 | 4.34 | 4.34 |
| 354.84 | 4.60 | 4.60 |
| 403.31 | 5.64 | 5.64 |
| 350.42 | 3.95 | 3.95 |
| 349.43 | 3.62 | 3.62 |
| 405.54 | 5.18 | 5.18 |
| 334.42 | 4.29 | 4.29 |
| 350.42 | 3.95 | 3.95 |
| 260.25 | 3.06 | 3.06 |
| 378.82 | 3.24 | 3.24 |
| 376.50 | 5.46 | 5.46 |
| 260.25 | 3.06 | 3.06 |
| 342.40 | 4.32 | 4.32 |
| 335.75 | 3.69 | 3.69 |
| 342.38 | 2.93 | 2.93 |
| 377.49 | 4.40 | 4.40 |
| 428.44 | 5.02 | 5.02 |
| 350.29 | 3.64 | 3.64 |
| 301.39 | 3.05 | 3.05 |
| 346.45 | 3.56 | 3.56 |
| 283.24 | 2.99 | 2.99 |
| 320.39 | 3.86 | 3.86 |
| 304.29 | 2.75 | 2.75 |
| 276.25 | 2.84 | 2.84 |
| 260.25 | 3.06 | 3.06 |
| 287.36 | 2.71 | 2.71 |
| 301.39 | 3.10 | 3.10 |
| 430.08 | 4.03 | 4.03 |
| 368.86 | 4.99 | 4.99 |
| 350.42 | 3.81 | 3.81 |
| 350.29 | 3.64 | 3.64 |
| 350.29 | 3.64 | 3.64 |
| 450.47 | 4.78 | 4.78 |
| 355.31 | 3.59 | 3.59 |
| 274.23 | 2.64 | 2.64 |
| 354.84 | 4.60 | 4.60 |
| 392.80 | 2.76 | 2.76 |
| 273.34 | 2.45 | 2.45 |
| 386.47 | 4.19 | 4.19 |
| 446.50 | 3.42 | 3.42 |
| 320.39 | 3.95 | 3.95 |
| 378.82 | 3.24 | 3.24 |
| 274.23 | 2.64 | 2.64 |
| 314.22 | 3.77 | 3.77 |
| 445.43 | 5.24 | 5.24 |
| 231.25 | 1.42 | 1.42 |
| 420.85 | 5.60 | 5.60 |
| 257.21 | 2.31 | 2.31 |
| 329.44 | 3.84 | 3.84 |
| 315.29 | 2.35 | 2.35 |
| 428.49 | 4.41 | 4.41 |
| 329.44 | 3.88 | 3.88 |
| 465.30 | 5.71 | 5.71 |
| 416.43 | 4.95 | 4.95 |
| 364.32 | 3.95 | 3.95 |
| 412.49 | 4.79 | 4.79 |
| 431.40 | 4.85 | 4.85 |
| 334.42 | 4.19 | 4.19 |
| 311.27 | 1.09 | 1.09 |
| 364.45 | 4.34 | 4.34 |
| 348.45 | 4.64 | 4.64 |
| 430.42 | 4.67 | 4.67 |
| 447.54 | 5.76 | 5.76 |
| 414.46 | 5.73 | 5.73 |
| 322.36 | 3.17 | 3.17 |
| 276.25 | 2.76 | 2.76 |
| 334.42 | 4.11 | 4.11 |
| 274.23 | 2.38 | 2.38 |
| 379.33 | 4.26 | 4.26 |
| 329.44 | 3.88 | 3.88 |
| 394.47 | 4.21 | 4.21 |
| 376.50 | 5.32 | 5.32 |
| 260.25 | 3.06 | 3.06 |