Basic Information
ID: ALA1794437
Type: Functional
Description: PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of farnesoid X receptor signaling. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA1794437
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 441.55 | 4.37 | 4.37 |
| 391.56 | 6.86 | 6.86 |
| 268.36 | 4.83 | 4.83 |
| 270.24 | 2.58 | 2.58 |
| 330.75 | 1.89 | 1.89 |
| 248.72 | 2.52 | 2.52 |
| 303.14 | 3.61 | 3.61 |
| 270.24 | 2.58 | 2.58 |
| 282.47 | 6.11 | 6.11 |
| 280.45 | 5.88 | 5.88 |
| 228.32 | 3.50 | 3.50 |
| 109.13 | 0.97 | 0.97 |
| 387.52 | 5.70 | 5.70 |
| 387.52 | 5.70 | 5.70 |
| 406.91 | 6.61 | 6.61 |
| 305.50 | 3.20 | 3.20 |
| 314.47 | 4.72 | 4.72 |
| 110.11 | 1.10 | 1.10 |
| 152.15 | 1.21 | 1.21 |
| 138.13 | 1.18 | 1.18 |
| 360.88 | 7.27 | 7.27 |
| 300.44 | 5.60 | 5.60 |
| 399.44 | 2.87 | 2.87 |
| 268.36 | 3.05 | 3.05 |
| 354.49 | 6.50 | 6.50 |
| 253.27 | 0.83 | 0.83 |
| 766.96 | 3.09 | 3.09 |
| 502.77 | 7.28 | 7.28 |
| 272.39 | 3.61 | 3.61 |
| 275.20 | 3.15 | 3.15 |
| 320.43 | 5.17 | 5.17 |
| 296.41 | 3.61 | 3.61 |
| 368.39 | 3.37 | 3.37 |
| 200.37 | 4.29 | 4.29 |
| 214.39 | 4.68 | 4.68 |
| 386.53 | 4.66 | 4.66 |
| 109.13 | 0.97 | 0.97 |
| 220.36 | 4.30 | 4.30 |
| 331.20 | 4.07 | 4.07 |
| 608.69 | 4.17 | 4.17 |
| 269.13 | 4.00 | 4.00 |
| 356.06 | 5.86 | 5.86 |
| 286.24 | 2.28 | 2.28 |
| 563.65 | 6.00 | 6.00 |
| 394.32 | 4.13 | 4.13 |
| 136.20 | 1.33 | 1.33 |
| 505.46 | 4.18 | 4.18 |
| 454.45 | 0.27 | 0.27 |
| 310.48 | 5.06 | 5.06 |
| 147.09 | -0.68 | -0.68 |
| 285.34 | 3.00 | 3.00 |
| 268.36 | 5.55 | 5.55 |
| 270.24 | 1.89 | 1.89 |
| 284.22 | 1.57 | 1.57 |
| 289.55 | 5.14 | 5.14 |
| 305.21 | 1.93 | 1.93 |
| 151.19 | 1.59 | 1.59 |
| 178.23 | 3.99 | 3.99 |
| 518.56 | 6.38 | 6.38 |
| 466.56 | 2.88 | 2.88 |
| 154.12 | -0.30 | -0.30 |
| 481.34 | 4.76 | 4.76 |
| 202.55 | 2.16 | 2.16 |
| 407.99 | 4.46 | 4.46 |
| 318.33 | 3.56 | 3.56 |
| 266.34 | 4.66 | 4.66 |
| 384.65 | 7.62 | 7.62 |
| 284.44 | 5.72 | 5.72 |
| 225.29 | 4.30 | 4.30 |
| 231.29 | 2.95 | 2.95 |
| 193.25 | 3.58 | 3.58 |
| 213.24 | 2.64 | 2.64 |
| 256.35 | 5.76 | 5.76 |
| 227.05 | 2.75 | 2.75 |
| 510.06 | 6.08 | 6.08 |
| 154.60 | 2.11 | 2.11 |
| 170.21 | 3.06 | 3.06 |
| 200.32 | 3.99 | 3.99 |
| 231.89 | 4.01 | 4.01 |
| 213.41 | 4.47 | 4.47 |
| 384.45 | 6.46 | 6.46 |
| 281.35 | 1.04 | 1.04 |
| 386.45 | 5.28 | 5.28 |
| 663.90 | 4.75 | 4.75 |
| 350.42 | 5.46 | 5.46 |
| 491.07 | 5.09 | 5.09 |
| 220.36 | 4.69 | 4.69 |
| 531.44 | 4.21 | 4.21 |
| 297.19 | 4.13 | 4.13 |
| 110.97 | 1.98 | 1.98 |
| 206.33 | 3.83 | 3.83 |
| 153.14 | 0.76 | 0.76 |
| 186.10 | 1.64 | 1.64 |
| 154.12 | 0.88 | 0.88 |
| 247.25 | 4.49 | 4.49 |
| 257.44 | 2.16 | 2.16 |
| 220.98 | 2.68 | 2.68 |
| 464.07 | 5.08 | 5.08 |
| 543.87 | 6.47 | 6.47 |
| 245.88 | 2.52 | 2.52 |
| 164.25 | 3.08 | 3.08 |
| 409.78 | 5.68 | 5.68 |
| 345.65 | 5.21 | 5.21 |
| 364.91 | 5.27 | 5.27 |
| 354.49 | 6.50 | 6.50 |
| 318.03 | 6.19 | 6.19 |
| 416.58 | 4.85 | 4.85 |
| 373.32 | 5.24 | 5.24 |
| 307.29 | 2.23 | 2.23 |
| 313.35 | 3.10 | 3.10 |
| 548.63 | 3.48 | 3.48 |
| 461.56 | 5.86 | 5.86 |
| 288.43 | 3.88 | 3.88 |
| 330.80 | 3.68 | 3.68 |
| 448.09 | 6.07 | 6.07 |
| 130.08 | -0.80 | -0.80 |
| 327.12 | 3.86 | 3.86 |
| 356.06 | 5.13 | 5.13 |
| 564.69 | 7.29 | 7.29 |
| 403.39 | 4.09 | 4.09 |
| 300.59 | 2.91 | 2.91 |
| 99.16 | 1.28 | 1.28 |
| 1134.99 | ||
| 376.58 | 5.51 | 5.51 |
| 228.25 | 2.82 | 2.82 |
| 764.95 | 3.25 | 3.25 |
| 346.34 | 2.18 | 2.18 |
| 345.42 | 2.90 | 2.90 |
| 312.45 | 4.64 | 4.64 |
| 391.29 | 6.11 | 6.11 |
| 376.37 | -1.72 | -1.72 |
| 340.42 | 3.57 | 3.57 |
| 650.98 | 3.95 | 3.95 |
| 295.34 | 4.86 | 4.86 |
| 1255.44 | ||
| 494.48 | 6.38 | 6.38 |
| 152.24 | 2.40 | 2.40 |
| 154.25 | 2.67 | 2.67 |
| 404.82 | ||
| 248.19 | 2.87 | 2.87 |
| 387.82 | 4.24 | 4.24 |
| 416.51 | ||
| 317.33 | 2.00 | 2.00 |
| 297.27 | -2.63 | -2.63 |
| 490.64 | 4.62 | 4.62 |
| 324.40 | 2.21 | 2.21 |
| 334.52 | 4.60 | 4.60 |
| 318.37 | 3.58 | 3.58 |
| 287.17 | 4.56 | 4.56 |
| 385.48 | ||
| 306.36 | 4.16 | 4.16 |
| 322.40 | 3.29 | 3.29 |
| 265.31 | ||
| 579.99 | 0.00 | 0.00 |
| 160.17 | 2.10 | 2.10 |
| 1229.32 | ||
| 349.43 | 5.27 | 5.27 |
| 406.27 | 4.67 | 4.67 |
| 596.12 | ||
| 230.31 | 5.02 | 5.02 |
| 244.21 | -3.01 | -3.01 |
| 265.91 | 4.04 | 4.04 |
| 376.67 | 4.60 | 4.60 |
| 414.47 | 6.06 | 6.06 |
| 320.05 | 5.93 | 5.93 |
| 295.81 | 2.58 | 2.58 |
| 326.29 | 5.33 | 5.33 |
| 316.88 | 3.88 | 3.88 |
| 199.26 | 2.84 | 2.84 |
| 307.26 | 5.75 | 5.75 |
| 373.91 | 2.50 | 2.50 |
| 142.59 | 1.50 | 1.50 |
| 274.27 | 2.27 | 2.27 |
| 184.24 | 3.01 | 3.01 |
| 780.95 | 2.22 | 2.22 |
| 403.82 | 2.57 | 2.57 |
| 315.59 | 5.29 | 5.29 |
| 303.85 | ||
| 325.51 | ||
| 294.39 | 3.53 | 3.53 |
| 527.41 | 7.18 | 7.18 |
| 330.36 | 2.12 | 2.12 |
| 317.71 | 0.61 | 0.61 |
| 332.48 | 4.40 | 4.40 |
| 340.29 | 4.19 | 4.19 |
| 313.87 | 4.17 | 4.17 |
| 192.52 | 1.40 | 1.40 |
| 249.71 | 2.66 | 2.66 |
| 444.70 | 5.80 | 5.80 |
| 598.09 | 6.56 | 6.56 |
| 204.18 | 1.95 | 1.95 |
| 391.56 | 6.86 | 6.86 |
| 311.41 | 3.49 | 3.49 |
| 488.59 | 5.20 | 5.20 |
| 106.12 | -1.01 | -1.01 |
| 295.34 | 4.01 | 4.01 |
| 429.60 | 5.41 | 5.41 |
| 344.39 | 1.43 | 1.43 |
| 284.31 | 0.68 | 0.68 |
| 303.36 | 4.24 | 4.24 |
| 259.18 | 2.21 | 2.21 |
| 216.28 | 4.89 | 4.89 |
| 260.34 | 5.17 | 5.17 |
| 336.74 | ||
| 244.21 | -3.17 | -3.17 |
| 287.17 | 3.83 | 3.83 |
| 252.32 | 5.64 | 5.64 |
| 222.24 | 1.24 | 1.24 |
| 230.26 | 2.30 | 2.30 |
| 415.54 | 4.35 | 4.35 |
| 294.18 | ||
| 240.67 | 1.50 | 1.50 |
| 154.17 | -0.45 | -0.45 |
| 211.65 | 2.07 | 2.07 |
| 220.36 | 4.11 | 4.11 |
| 269.77 | 2.99 | 2.99 |
| 350.48 | 3.92 | 3.92 |
| 430.56 | 3.45 | 3.45 |
| 155.16 | 1.56 | 1.56 |
| 266.53 | ||
| 252.32 | 5.64 | 5.64 |
| 302.28 | 1.32 | 1.32 |
| 226.32 | 4.25 | 4.25 |
| 217.44 | 1.16 | 1.16 |
| 78.07 | 0.59 | 0.59 |
| 164.25 | 2.12 | 2.12 |
| 365.96 | 5.60 | 5.60 |
| 282.19 | ||
| 178.02 | 2.28 | 2.28 |
| 616.79 | 3.41 | 3.41 |
| 183.32 | ||
| 428.48 | 1.62 | 1.62 |
| 197.45 | 3.35 | 3.35 |
| 296.28 | 3.31 | 3.31 |
| 350.46 | 6.20 | 6.20 |
| 302.32 | 0.49 | 0.49 |
| 195.22 | 1.88 | 1.88 |
| 172.21 | -0.73 | -0.73 |
| 214.22 | 0.46 | 0.46 |
| 546.81 | 11.25 | 11.25 |
| 305.83 | 0.76 | 0.76 |
| 130.20 | 1.37 | 1.37 |
| 358.55 | 6.46 | 6.46 |
| 306.49 | 6.14 | 6.14 |
| 801.38 | 9.58 | 9.58 |
| 552.58 | 5.40 | 5.40 |
| 398.48 | 4.59 | 4.59 |
| 330.21 | 1.69 | 1.69 |
| 927.02 | 4.39 | 4.39 |
| 268.40 | 5.28 | 5.28 |
| 213.35 | 3.27 | 3.27 |
| 188.01 | 2.96 | 2.96 |
| 268.36 | 4.16 | 4.16 |
| 411.80 | 5.38 | 5.38 |
| 643.59 | 8.05 | 8.05 |
| 223.49 | 3.41 | 3.41 |
| 197.45 | 3.35 | 3.35 |
| 150.18 | 2.15 | 2.15 |
| 251.08 | ||
| 284.44 | 5.72 | 5.72 |
| 269.30 | 4.07 | 4.07 |
| 198.22 | 3.83 | 3.83 |
| 298.29 | 0.15 | 0.15 |
| 410.45 | 7.18 | 7.18 |
| 326.05 | 3.82 | 3.82 |
| 303.84 | 3.23 | 3.23 |
| 267.31 | 1.30 | 1.30 |
| 126.59 | 2.65 | 2.65 |
| 374.40 | 4.70 | 4.70 |
| 324.79 | 2.04 | 2.04 |
| 163.26 | 3.00 | 3.00 |
| 324.68 | 2.73 | 2.73 |
| 639.83 | 5.73 | 5.73 |
| 384.52 | 6.19 | 6.19 |
| 407.62 | 5.46 | 5.46 |
| 308.14 | 5.47 | 5.47 |
| 326.23 | 3.99 | 3.99 |
| 361.70 | 5.46 | 5.46 |
| 302.41 | 4.00 | 4.00 |
| 380.91 | 4.48 | 4.48 |
| 294.31 | 3.62 | 3.62 |
| 351.03 | ||
| 207.11 | 2.32 | 2.32 |
| 465.09 | 5.99 | 5.99 |
| 364.91 | 5.27 | 5.27 |
| 914.14 | 5.52 | 5.52 |
| 336.83 | 4.03 | 4.03 |
| 351.49 | 5.50 | 5.50 |
| 168.96 | 0.96 | 0.96 |
| 276.34 | 6.33 | 6.33 |
| 411.17 | ||
| 409.78 | 5.68 | 5.68 |
| 359.42 | 5.18 | 5.18 |
| 513.59 | 4.94 | 4.94 |
| 296.56 | 3.26 | 3.26 |
| 1008.26 | 5.60 | 5.60 |
| 422.03 | 2.92 | 2.92 |
| 304.67 | 4.84 | 4.84 |
| 185.23 | 3.14 | 3.14 |
| 203.02 | 2.44 | 2.44 |
| 296.32 | 1.57 | 1.57 |
| 164.21 | 2.04 | 2.04 |
| 255.21 | -0.23 | -0.23 |
| 542.71 | 4.92 | 4.92 |
| 377.07 | 3.66 | 3.66 |
| 385.18 | ||
| 728.78 | -1.51 | -1.51 |
| 204.34 | 2.68 | 2.68 |
| 406.93 | 3.69 | 3.69 |
| 375.73 | 4.49 | 4.49 |
| 305.45 | 4.18 | 4.18 |
| 496.47 | -1.24 | -1.24 |
| 247.68 | 3.30 | 3.30 |
| 545.33 | 10.91 | 10.91 |
| 240.22 | 2.72 | 2.72 |
| 349.07 | 3.52 | 3.52 |
| 214.35 | 4.08 | 4.08 |
| 397.52 | 3.77 | 3.77 |
| 351.85 | ||
| 502.92 | 7.40 | 7.40 |
| 333.86 | 3.86 | 3.86 |
| 408.38 | 4.17 | 4.17 |
| 541.08 | ||
| 330.48 | 5.00 | 5.00 |
| 315.40 | ||
| 187.63 | 1.94 | 1.94 |
| 577.93 | 6.58 | 6.58 |
| 527.84 | 4.09 | 4.09 |
| 458.83 | 4.56 | 4.56 |
| 188.08 | ||
| 290.06 | ||
| 238.36 | 3.56 | 3.56 |
| 260.68 | 2.64 | 2.64 |
| 697.61 | 5.62 | 5.62 |
| 388.85 | 3.23 | 3.23 |
| 347.00 | ||
| 285.80 | ||
| 298.30 | 3.23 | 3.23 |
| 602.81 | 4.17 | 4.17 |
| 1732.15 | ||
| 676.84 | 3.03 | 3.03 |