Basic Information
ID: ALA1794438
Type: Binding
Description: PUBCHEM_BIOASSAY: Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504734, AID504750, AID540250, AID540251]
Activity Charts
Bioactivity
Activity Types for Assay ALA1794438
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 368.39 | 3.37 | 3.37 |
| 311.38 | 3.67 | 3.67 |
| 237.26 | 2.42 | 2.42 |
| 368.39 | 3.85 | 3.85 |
| 308.33 | 3.84 | 3.84 |
| 287.10 | 2.77 | 2.77 |
| 267.33 | 3.35 | 3.35 |
| 226.24 | 2.75 | 2.75 |
| 338.36 | 3.84 | 3.84 |
| 310.40 | 1.73 | 1.73 |
| 282.32 | 3.02 | 3.02 |
| 404.82 | ||
| 280.37 | 3.58 | 3.58 |
| 290.26 | 1.92 | 1.92 |
| 610.73 | 7.85 | 7.85 |
| 332.16 | 2.56 | 2.56 |
| 401.88 | 3.66 | 3.66 |
| 339.35 | 4.19 | 4.19 |
| 229.16 | 2.39 | 2.39 |
| 400.78 | 3.33 | 3.33 |
| 422.46 | 3.24 | 3.24 |
| 415.90 | 3.92 | 3.92 |
| 408.57 | 4.84 | 4.84 |
| 306.67 | 3.23 | 3.23 |
| 462.83 | 6.70 | 6.70 |
| 324.38 | 3.67 | 3.67 |
| 410.52 | 5.16 | 5.16 |
| 329.47 | 3.06 | 3.06 |
| 402.04 | 3.41 | 3.41 |
| 306.67 | 3.23 | 3.23 |
| 357.84 | 1.83 | 1.83 |
| 311.72 | 3.00 | 3.00 |
| 480.96 | 2.61 | 2.61 |
| 396.86 | 1.62 | 1.62 |
| 487.00 | 2.60 | 2.60 |
| 427.48 | 5.72 | 5.72 |
| 252.66 | 2.58 | 2.58 |
| 313.14 | 2.67 | 2.67 |
| 290.37 | 3.10 | 3.10 |
| 241.29 | 2.49 | 2.49 |
| 279.78 | 3.86 | 3.86 |
| 425.87 | 3.17 | 3.17 |
| 442.46 | 3.91 | 3.91 |
| 444.53 | 2.60 | 2.60 |
| 448.16 | 5.26 | 5.26 |
| 351.42 | 2.52 | 2.52 |
| 251.24 | 1.88 | 1.88 |
| 277.28 | 2.35 | 2.35 |
| 392.01 | 1.56 | 1.56 |
| 290.32 | 5.06 | 5.06 |
| 354.82 | 4.84 | 4.84 |
| 320.27 | 2.71 | 2.71 |
| 419.87 | 3.80 | 3.80 |
| 406.42 | 2.77 | 2.77 |
| 390.46 | 4.79 | 4.79 |
| 408.53 | 5.47 | 5.47 |
| 380.49 | 5.16 | 5.16 |
| 494.58 | 6.03 | 6.03 |
| 447.90 | 3.37 | 3.37 |
| 323.42 | 3.78 | 3.78 |
| 245.28 | 3.19 | 3.19 |
| 407.48 | 4.27 | 4.27 |
| 487.00 | 2.74 | 2.74 |
| 329.83 | 2.50 | 2.50 |
| 240.27 | 1.99 | 1.99 |
| 438.36 | 2.97 | 2.97 |
| 476.53 | 4.00 | 4.00 |
| 389.42 | 3.30 | 3.30 |
| 334.44 | 5.11 | 5.11 |
| 392.33 | 2.64 | 2.64 |
| 310.25 | 3.35 | 3.35 |
| 376.32 | 3.47 | 3.47 |
| 405.40 | 5.32 | 5.32 |
| 341.78 | 1.79 | 1.79 |
| 301.26 | 0.38 | 0.38 |
| 331.42 | 2.94 | 2.94 |
| 285.31 | 1.69 | 1.69 |
| 363.85 | 3.61 | 3.61 |
| 319.67 | 2.09 | 2.09 |
| 444.90 | 3.31 | 3.31 |
| 494.98 | 3.00 | 3.00 |
| 388.37 | 2.89 | 2.89 |
| 251.29 | 2.72 | 2.72 |
| 431.30 | 3.30 | 3.30 |
| 542.70 | 5.59 | 5.59 |
| 568.67 | 5.59 | 5.59 |
| 374.68 | 4.73 | 4.73 |
| 301.78 | 1.72 | 1.72 |
| 420.53 | 4.71 | 4.71 |
| 374.34 | 2.50 | 2.50 |
| 330.23 | 4.41 | 4.41 |
| 376.29 | 4.33 | 4.33 |
| 289.55 | 3.50 | 3.50 |
| 378.82 | 4.00 | 4.00 |
| 345.83 | 2.16 | 2.16 |
| 294.40 | 3.83 | 3.83 |
| 277.75 | 3.43 | 3.43 |
| 317.37 | 4.68 | 4.68 |
| 409.63 | 4.81 | 4.81 |
| 390.46 | 4.79 | 4.79 |
| 288.33 | 3.62 | 3.62 |
| 312.39 | 4.11 | 4.11 |
| 339.80 | 2.48 | 2.48 |
| 324.42 | 4.45 | 4.45 |
| 254.72 | 2.24 | 2.24 |
| 265.07 | 1.75 | 1.75 |
| 484.00 | 7.28 | 7.28 |
| 419.87 | 3.80 | 3.80 |
| 367.89 | 5.80 | 5.80 |
| 361.81 | 2.94 | 2.94 |
| 298.29 | 3.18 | 3.18 |
| 545.27 | 4.26 | 4.26 |
| 459.91 | 3.53 | 3.53 |
| 420.53 | 4.86 | 4.86 |
| 302.28 | 2.57 | 2.57 |
| 274.33 | 3.67 | 3.67 |
| 419.72 | 4.28 | 4.28 |
| 418.25 | 4.95 | 4.95 |
| 349.48 | 4.60 | 4.60 |
| 238.63 | 2.10 | 2.10 |
| 390.45 | 4.71 | 4.71 |
| 302.33 | 3.08 | 3.08 |
| 405.84 | 3.50 | 3.50 |
| 380.49 | 4.62 | 4.62 |
| 462.51 | 7.42 | 7.42 |
| 364.40 | 4.33 | 4.33 |
| 459.91 | 3.45 | 3.45 |
| 341.43 | 4.43 | 4.43 |
| 297.36 | 4.55 | 4.55 |
| 458.93 | 3.62 | 3.62 |
| 347.42 | 4.19 | 4.19 |
| 308.34 | 3.52 | 3.52 |
| 386.46 | 3.76 | 3.76 |
| 333.35 | 4.54 | 4.54 |
| 331.80 | 3.70 | 3.70 |
| 350.33 | 1.46 | 1.46 |
| 358.28 | 5.19 | 5.19 |
| 196.21 | 2.51 | 2.51 |
| 384.23 | 3.75 | 3.75 |
| 214.57 | 1.37 | 1.37 |
| 359.39 | 4.66 | 4.66 |
| 376.32 | 3.56 | 3.56 |
| 391.88 | 3.03 | 3.03 |
| 373.82 | 1.84 | 1.84 |
| 396.56 | 4.69 | 4.69 |
| 429.93 | 4.28 | 4.28 |
| 354.36 | 2.38 | 2.38 |
| 336.46 | 4.94 | 4.94 |
| 311.30 | 2.97 | 2.97 |
| 333.56 | 3.02 | 3.02 |
| 327.38 | 2.76 | 2.76 |
| 264.69 | 0.71 | 0.71 |
| 618.68 | 6.47 | 6.47 |
| 347.31 | 2.35 | 2.35 |
| 346.83 | 3.47 | 3.47 |
| 377.76 | 2.39 | 2.39 |
| 372.42 | 4.34 | 4.34 |
| 592.64 | 3.00 | 3.00 |
| 403.45 | 3.32 | 3.32 |
| 382.46 | 3.98 | 3.98 |
| 392.40 | 2.38 | 2.38 |
| 401.88 | 3.66 | 3.66 |
| 429.86 | 3.96 | 3.96 |
| 376.32 | 3.47 | 3.47 |
| 385.27 | 3.62 | 3.62 |
| 521.74 | 5.89 | 5.89 |
| 278.30 | 0.46 | 0.46 |
| 301.30 | 3.03 | 3.03 |
| 517.48 | 4.75 | 4.75 |
| 484.56 | ||
| 419.44 | 2.39 | 2.39 |
| 228.59 | 1.83 | 1.83 |
| 372.42 | 4.34 | 4.34 |
| 368.40 | 2.24 | 2.24 |
| 443.48 | 5.42 | 5.42 |
| 280.33 | 3.93 | 3.93 |
| 254.29 | 3.70 | 3.70 |
| 425.44 | 3.31 | 3.31 |
| 414.40 | 3.13 | 3.13 |
| 445.48 | 4.26 | 4.26 |
| 306.67 | 3.23 | 3.23 |
| 316.41 | 4.84 | 4.84 |
| 267.26 | 2.33 | 2.33 |
| 346.49 | 1.96 | 1.96 |
| 284.70 | 3.60 | 3.60 |
| 334.42 | 2.96 | 2.96 |
| 272.29 | 2.96 | 2.96 |
| 277.71 | 2.43 | 2.43 |
| 332.40 | 3.65 | 3.65 |
| 371.39 | 3.95 | 3.95 |
| 284.34 | 3.01 | 3.01 |
| 336.43 | 3.02 | 3.02 |
| 298.25 | 0.55 | 0.55 |
| 306.30 | 2.81 | 2.81 |
| 372.44 | 3.83 | 3.83 |
| 450.62 | 6.70 | 6.70 |
| 221.26 | 2.88 | 2.88 |
| 380.45 | 4.71 | 4.71 |
| 313.36 | 3.28 | 3.28 |
| 311.77 | 3.35 | 3.35 |
| 282.34 | 3.06 | 3.06 |
| 540.64 | 5.05 | 5.05 |
| 295.29 | 4.07 | 4.07 |
| 406.48 | 0.95 | 0.95 |
| 398.42 | 1.53 | 1.53 |
| 332.40 | 1.96 | 1.96 |
| 342.40 | 2.73 | 2.73 |
| 342.81 | 3.33 | 3.33 |
| 372.30 | 2.86 | 2.86 |
| 392.45 | 3.66 | 3.66 |
| 268.23 | 0.55 | 0.55 |
| 318.33 | 2.65 | 2.65 |
| 482.65 | 5.95 | 5.95 |
| 355.78 | 3.58 | 3.58 |
| 285.30 | 3.78 | 3.78 |
| 465.49 | 4.33 | 4.33 |
| 611.69 | 5.47 | 5.47 |
| 257.25 | 3.30 | 3.30 |
| 1301.83 | ||
| 520.62 | 6.57 | 6.57 |
| 546.98 | 6.47 | 6.47 |
| 494.58 | 6.03 | 6.03 |
| 280.29 | 3.52 | 3.52 |
| 379.29 | 2.93 | 2.93 |
| 332.40 | 4.26 | 4.26 |
| 295.30 | 4.18 | 4.18 |
| 451.11 | 5.35 | 5.35 |
| 500.52 | 3.93 | 3.93 |
| 330.82 | 2.33 | 2.33 |
| 363.42 | 4.46 | 4.46 |
| 526.63 | 6.29 | 6.29 |
| 287.28 | 2.76 | 2.76 |
| 309.34 | 4.14 | 4.14 |
| 378.30 | 3.46 | 3.46 |
| 299.29 | 3.16 | 3.16 |