Basic Information
ID: ALA1794455
Type: Functional
Description: PUBCHEM_BIOASSAY: SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2540, AID2575]
Activity Charts
Bioactivity
Activity Types for Assay ALA1794455
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 296.30 | 2.81 | 2.81 |
| 293.33 | 2.37 | 2.37 |
| 278.72 | 3.80 | 3.80 |
| 310.40 | 4.76 | 4.76 |
| 298.73 | 4.27 | 4.27 |
| 321.34 | 3.57 | 3.57 |
| 249.27 | 3.30 | 3.30 |
| 371.42 | 1.36 | 1.36 |
| 304.35 | 3.33 | 3.33 |
| 280.28 | 3.32 | 3.32 |
| 328.37 | 2.02 | 2.02 |
| 307.35 | 3.68 | 3.68 |
| 282.27 | 3.75 | 3.75 |
| 252.73 | 3.30 | 3.30 |
| 294.31 | 3.62 | 3.62 |
| 377.44 | 3.02 | 3.02 |
| 292.75 | 4.10 | 4.10 |
| 384.46 | 2.30 | 2.30 |
| 286.33 | 1.99 | 1.99 |
| 264.28 | 3.61 | 3.61 |
| 459.55 | 5.05 | 5.05 |
| 302.26 | 4.32 | 4.32 |
| 375.43 | 2.89 | 2.89 |
| 261.33 | 3.01 | 3.01 |
| 260.34 | 3.61 | 3.61 |
| 316.45 | 4.95 | 4.95 |
| 350.90 | 5.61 | 5.61 |
| 316.74 | 3.98 | 3.98 |
| 347.24 | 4.34 | 4.34 |
| 497.55 | 4.13 | 4.13 |
| 291.76 | 3.54 | 3.54 |
| 313.43 | 4.23 | 4.23 |
| 266.27 | 4.05 | 4.05 |
| 512.99 | 7.37 | 7.37 |
| 278.31 | 3.92 | 3.92 |
| 496.53 | 2.54 | 2.54 |
| 323.38 | 3.82 | 3.82 |
| 274.37 | 3.92 | 3.92 |
| 368.35 | 3.08 | 3.08 |
| 362.43 | 3.98 | 3.98 |
| 431.54 | 3.31 | 3.31 |
| 412.88 | 5.73 | 5.73 |
| 476.03 | 4.32 | 4.32 |
| 284.36 | 3.14 | 3.14 |
| 294.79 | 4.26 | 4.26 |
| 392.17 | 4.65 | 4.65 |
| 260.34 | 3.61 | 3.61 |
| 399.41 | 4.38 | 4.38 |
| 430.27 | 4.63 | 4.63 |
| 284.36 | 3.06 | 3.06 |
| 333.35 | 3.82 | 3.82 |
| 317.44 | 4.35 | 4.35 |
| 379.46 | 4.62 | 4.62 |
| 471.61 | 3.67 | 3.67 |
| 330.48 | 5.26 | 5.26 |
| 431.58 | 4.30 | 4.30 |
| 386.47 | 5.36 | 5.36 |
| 329.23 | 4.92 | 4.92 |
| 361.40 | 2.36 | 2.36 |
| 345.40 | 3.43 | 3.43 |
| 335.41 | 4.46 | 4.46 |
| 262.31 | 4.22 | 4.22 |
| 336.38 | 2.83 | 2.83 |
| 295.78 | 3.66 | 3.66 |
| 379.28 | 5.25 | 5.25 |
| 419.27 | 3.12 | 3.12 |
| 329.40 | 1.50 | 1.50 |
| 381.45 | 3.80 | 3.80 |
| 343.39 | 4.10 | 4.10 |
| 294.79 | 4.26 | 4.26 |
| 348.41 | 3.35 | 3.35 |
| 381.82 | 4.87 | 4.87 |
| 416.40 | 3.85 | 3.85 |
| 528.66 | 3.86 | 3.86 |
| 351.39 | 3.38 | 3.38 |
| 300.38 | 4.48 | 4.48 |
| 345.36 | 3.88 | 3.88 |
| 269.33 | 2.99 | 2.99 |
| 478.60 | 4.06 | 4.06 |
| 262.31 | 4.22 | 4.22 |
| 266.27 | 4.05 | 4.05 |
| 342.44 | 1.49 | 1.49 |
| 278.33 | 3.75 | 3.75 |
| 473.53 | 4.56 | 4.56 |
| 390.32 | 3.79 | 3.79 |
| 316.45 | 4.95 | 4.95 |
| 319.32 | 2.34 | 2.34 |
| 303.37 | 3.42 | 3.42 |
| 298.73 | 4.27 | 4.27 |
| 284.27 | 4.19 | 4.19 |
| 394.46 | 3.87 | 3.87 |
| 377.26 | 4.63 | 4.63 |
| 305.31 | 4.25 | 4.25 |
| 456.30 | 3.18 | 3.18 |
| 491.47 | 6.72 | 6.72 |
| 359.39 | 3.63 | 3.63 |
| 266.28 | 4.05 | 4.05 |
| 510.06 | 5.09 | 5.09 |
| 326.78 | 3.76 | 3.76 |
| 314.37 | 1.60 | 1.60 |
| 376.42 | 2.68 | 2.68 |