Basic Information
ID: ALA1794491
Type: Functional
Description: PUBCHEM_BIOASSAY: Counterscreen for agonists of OPRM1-OPRD1 heterodimerization: luminescence-based cell-based high throughput dose response assay to identify agonists of 5-hydroxytryptamine (serotonin) 5A receptor (HTR5A). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504326, AID504355, AID504692, AID504904, AID504905]
Activity Charts
Bioactivity
Activity Types for Assay ALA1794491
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 299.77 | 0.57 | 0.57 |
| 279.86 | 4.33 | 4.33 |
| 360.64 | 5.10 | 5.10 |
| 548.67 | 2.29 | 2.29 |
| 455.03 | 5.52 | 5.52 |
| 594.71 | 6.56 | 6.56 |
| 314.39 | 5.53 | 5.53 |
| 452.99 | 1.38 | 1.38 |
| 687.71 | 10.29 | 10.29 |
| 521.51 | 4.56 | 4.56 |
| 501.84 | 4.29 | 4.29 |
| 391.47 | 5.48 | 5.48 |
| 326.32 | 3.33 | 3.33 |
| 393.53 | 4.18 | 4.18 |
| 452.56 | 3.82 | 3.82 |
| 328.49 | 3.70 | 3.70 |
| 314.46 | 3.39 | 3.39 |
| 345.41 | 4.01 | 4.01 |
| 462.83 | 6.70 | 6.70 |
| 503.55 | 3.74 | 3.74 |
| 235.25 | -0.67 | -0.67 |
| 337.22 | 3.07 | 3.07 |
| 405.36 | 3.21 | 3.21 |
| 497.55 | 5.59 | 5.59 |
| 443.59 | 6.17 | 6.17 |
| 403.53 | 3.94 | 3.94 |
| 393.51 | 4.22 | 4.22 |
| 342.44 | 2.88 | 2.88 |
| 388.53 | 4.07 | 4.07 |
| 301.19 | 4.54 | 4.54 |
| 325.88 | 3.50 | 3.50 |
| 409.56 | 4.32 | 4.32 |
| 383.48 | 3.76 | 3.76 |
| 409.92 | 4.91 | 4.91 |
| 379.44 | 4.09 | 4.09 |
| 544.68 | 5.47 | 5.47 |
| 477.08 | 3.70 | 3.70 |
| 419.91 | 5.00 | 5.00 |
| 435.91 | 3.48 | 3.48 |
| 361.49 | 4.24 | 4.24 |
| 487.08 | 6.04 | 6.04 |
| 298.41 | 3.44 | 3.44 |
| 390.53 | 5.71 | 5.71 |
| 412.60 | 4.26 | 4.26 |
| 327.50 | 4.30 | 4.30 |
| 402.47 | 4.68 | 4.68 |
| 433.55 | 4.49 | 4.49 |
| 424.54 | 3.46 | 3.46 |
| 346.38 | 3.12 | 3.12 |
| 338.24 | 3.42 | 3.42 |
| 404.43 | 4.76 | 4.76 |
| 384.48 | 1.69 | 1.69 |
| 439.60 | 4.59 | 4.59 |
| 290.41 | 2.32 | 2.32 |
| 387.32 | 4.79 | 4.79 |
| 388.45 | 4.37 | 4.37 |
| 577.15 | 4.85 | 4.85 |
| 398.57 | 5.29 | 5.29 |
| 333.89 | 4.34 | 4.34 |
| 338.43 | 4.02 | 4.02 |
| 393.90 | 5.61 | 5.61 |
| 423.94 | 3.72 | 3.72 |
| 410.99 | 4.74 | 4.74 |
| 311.41 | 3.92 | 3.92 |
| 391.33 | 2.90 | 2.90 |
| 429.95 | 5.33 | 5.33 |
| 331.42 | 4.09 | 4.09 |
| 383.45 | 2.63 | 2.63 |
| 357.37 | 3.72 | 3.72 |
| 601.24 | 5.72 | 5.72 |
| 383.50 | 4.28 | 4.28 |
| 474.65 | 3.91 | 3.91 |
| 406.44 | 3.86 | 3.86 |
| 440.34 | 4.71 | 4.71 |
| 340.86 | 3.55 | 3.55 |
| 358.51 | 3.51 | 3.51 |
| 471.92 | 3.04 | 3.04 |
| 438.02 | 4.48 | 4.48 |
| 405.52 | 1.98 | 1.98 |
| 419.50 | 4.50 | 4.50 |
| 303.77 | 3.16 | 3.16 |
| 387.55 | 4.67 | 4.67 |
| 373.41 | 3.26 | 3.26 |
| 343.90 | 4.55 | 4.55 |
| 400.50 | 2.96 | 2.96 |
| 425.53 | 4.07 | 4.07 |
| 397.95 | 4.04 | 4.04 |
| 585.20 | 4.95 | 4.95 |
| 582.70 | 5.91 | 5.91 |
| 389.48 | 4.57 | 4.57 |
| 380.47 | 4.63 | 4.63 |
| 341.45 | 4.06 | 4.06 |
| 516.69 | 6.15 | 6.15 |
| 480.55 | 3.75 | 3.75 |
| 408.41 | 3.33 | 3.33 |
| 417.38 | 4.78 | 4.78 |
| 461.55 | 4.76 | 4.76 |
| 336.44 | 4.05 | 4.05 |
| 371.55 | 3.92 | 3.92 |
| 445.52 | 4.07 | 4.07 |
| 429.54 | 4.12 | 4.12 |
| 525.26 | 4.39 | 4.39 |
| 412.58 | 2.86 | 2.86 |
| 393.50 | 3.94 | 3.94 |
| 344.46 | 3.63 | 3.63 |
| 484.63 | 5.45 | 5.45 |
| 486.62 | 4.58 | 4.58 |
| 495.85 | 4.37 | 4.37 |
| 467.59 | 3.92 | 3.92 |
| 569.17 | 4.99 | 4.99 |
| 386.46 | 3.76 | 3.76 |
| 405.59 | 4.98 | 4.98 |
| 385.52 | 4.53 | 4.53 |
| 369.51 | 3.59 | 3.59 |
| 372.51 | 4.13 | 4.13 |
| 398.89 | 3.43 | 3.43 |
| 399.45 | 4.33 | 4.33 |
| 371.48 | 4.13 | 4.13 |
| 579.23 | 5.41 | 5.41 |
| 497.39 | 4.93 | 4.93 |
| 391.33 | 2.90 | 2.90 |
| 409.92 | 3.98 | 3.98 |
| 429.53 | 2.62 | 2.62 |
| 375.52 | 4.08 | 4.08 |
| 423.94 | 3.72 | 3.72 |
| 433.59 | 6.36 | 6.36 |
| 471.56 | 6.29 | 6.29 |
| 538.74 | 5.30 | 5.30 |
| 412.89 | 3.48 | 3.48 |
| 573.13 | 4.74 | 4.74 |
| 356.50 | 4.03 | 4.03 |
| 337.33 | 2.88 | 2.88 |
| 413.56 | 5.22 | 5.22 |
| 659.63 | 6.93 | 6.93 |
| 432.59 | 4.82 | 4.82 |
| 418.50 | 4.96 | 4.96 |
| 589.16 | 4.78 | 4.78 |
| 391.51 | 4.77 | 4.77 |
| 370.24 | 5.03 | 5.03 |
| 341.44 | 3.96 | 3.96 |
| 531.66 | 4.13 | 4.13 |
| 446.56 | 3.81 | 3.81 |
| 363.40 | 2.36 | 2.36 |
| 369.51 | 4.48 | 4.48 |
| 552.61 | 5.30 | 5.30 |
| 403.51 | 4.88 | 4.88 |
| 343.43 | 2.27 | 2.27 |
| 400.43 | 5.25 | 5.25 |
| 300.40 | 2.86 | 2.86 |
| 448.53 | 4.44 | 4.44 |
| 443.57 | 3.70 | 3.70 |
| 418.50 | 6.54 | 6.54 |
| 458.51 | 3.79 | 3.79 |
| 308.38 | 3.47 | 3.47 |
| 402.38 | 4.16 | 4.16 |
| 414.46 | 3.83 | 3.83 |
| 326.44 | 3.18 | 3.18 |
| 607.15 | 4.92 | 4.92 |
| 374.24 | 5.17 | 5.17 |
| 408.54 | 4.42 | 4.42 |
| 599.22 | 5.20 | 5.20 |
| 334.88 | 3.74 | 3.74 |
| 526.10 | 4.55 | 4.55 |
| 453.99 | 3.41 | 3.41 |
| 361.28 | 3.41 | 3.41 |
| 334.88 | 3.74 | 3.74 |
| 532.53 | 3.55 | 3.55 |
| 425.55 | 4.03 | 4.03 |
| 339.28 | 3.44 | 3.44 |
| 592.70 | 5.65 | 5.65 |
| 300.43 | 3.08 | 3.08 |
| 326.32 | 3.33 | 3.33 |
| 387.55 | 4.07 | 4.07 |
| 386.50 | 3.93 | 3.93 |
| 471.43 | 4.89 | 4.89 |
| 378.27 | 2.89 | 2.89 |
| 260.34 | 4.79 | 4.79 |
| 351.54 | 2.52 | 2.52 |
| 327.38 | 2.56 | 2.56 |
| 373.91 | 1.98 | 1.98 |
| 332.47 | 3.11 | 3.11 |
| 314.46 | 3.39 | 3.39 |
| 337.46 | 3.67 | 3.67 |
| 393.53 | 4.40 | 4.40 |
| 406.53 | 4.38 | 4.38 |
| 300.31 | 3.74 | 3.74 |
| 754.88 | 6.02 | 6.02 |
| 849.52 | 9.09 | 9.09 |
| 403.53 | 4.26 | 4.26 |
| 544.63 | 3.72 | 3.72 |
| 375.52 | 3.87 | 3.87 |
| 342.51 | 3.76 | 3.76 |
| 427.55 | 5.04 | 5.04 |
| 481.98 | 4.40 | 4.40 |
| 643.77 | 1.98 | 1.98 |
| 456.42 | 5.26 | 5.26 |
| 300.81 | 4.47 | 4.47 |
| 298.34 | 3.06 | 3.06 |
| 758.84 | 9.31 | 9.31 |
| 449.64 | 4.85 | 4.85 |
| 473.25 | 3.10 | 3.10 |
| 365.48 | 2.45 | 2.45 |
| 338.45 | 3.22 | 3.22 |
| 546.16 | 7.01 | 7.01 |
| 351.83 | 1.05 | 1.05 |
| 518.89 | 4.49 | 4.49 |
| 354.45 | 3.12 | 3.12 |
| 518.09 | 4.47 | 4.47 |
| 375.94 | 4.28 | 4.28 |
| 398.48 | 3.75 | 3.75 |
| 533.52 | 2.74 | 2.74 |
| 533.52 | 2.74 | 2.74 |
| 347.41 | 2.55 | 2.55 |
| 327.41 | 3.76 | 3.76 |
| 546.80 | 5.15 | 5.15 |
| 489.62 | 5.07 | 5.07 |
| 408.41 | 3.33 | 3.33 |
| 492.33 | 4.98 | 4.98 |
| 304.35 | 4.02 | 4.02 |
| 291.33 | 2.22 | 2.22 |
| 476.21 | 3.78 | 3.78 |
| 402.50 | 3.21 | 3.21 |
| 310.79 | 4.31 | 4.31 |
| 544.63 | 3.03 | 3.03 |
| 380.45 | 3.25 | 3.25 |
| 418.48 | 3.77 | 3.77 |
| 389.43 | 3.93 | 3.93 |
| 318.47 | 3.75 | 3.75 |