Basic Information
ID: ALA1794508
Type: Functional
Description: PUBCHEM_BIOASSAY: Counterscreen for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): luminescence-based cell-based high throughput dose response assay to identify compounds that interfere with the UAS/Gal4 system and/or luciferase reporter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504766, AID504790]
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1794508
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 263.26 | -1.40 | -1.40 |
| 264.32 | 2.47 | 2.47 |
| 370.16 | -0.74 | -0.74 |
| 252.27 | 3.47 | 3.47 |
| 290.32 | 3.01 | 3.01 |
| 286.24 | 2.28 | 2.28 |
| 238.24 | 3.17 | 3.17 |
| 212.20 | 1.41 | 1.41 |
| 404.92 | 3.02 | 3.02 |
| 408.82 | 4.44 | 4.44 |
| 261.71 | 2.89 | 2.89 |
| 317.37 | 3.40 | 3.40 |
| 256.30 | 2.81 | 2.81 |
| 279.39 | 3.42 | 3.42 |
| 282.33 | 2.85 | 2.85 |
| 349.11 | 5.47 | 5.47 |
| 398.41 | 2.85 | 2.85 |
| 327.19 | 4.68 | 4.68 |
| 247.26 | 0.84 | 0.84 |
| 330.73 | 3.75 | 3.75 |
| 250.32 | 1.92 | 1.92 |
| 311.36 | 1.75 | 1.75 |
| 347.35 | 1.49 | 1.49 |
| 318.81 | 2.22 | 2.22 |
| 348.45 | 3.64 | 3.64 |
| 389.53 | 3.80 | 3.80 |
| 300.31 | 3.79 | 3.79 |
| 509.44 | 2.87 | 2.87 |
| 338.45 | 3.01 | 3.01 |
| 457.60 | 2.75 | 2.75 |
| 350.83 | 2.91 | 2.91 |
| 340.79 | 3.76 | 3.76 |
| 287.32 | 3.19 | 3.19 |
| 318.29 | -0.06 | -0.06 |
| 316.41 | 4.24 | 4.24 |
| 313.29 | 3.78 | 3.78 |
| 326.42 | 3.86 | 3.86 |
| 331.40 | 2.78 | 2.78 |
| 227.27 | 2.10 | 2.10 |
| 272.37 | 3.14 | 3.14 |
| 294.36 | 2.33 | 2.33 |
| 269.30 | 3.69 | 3.69 |
| 372.34 | 1.31 | 1.31 |
| 271.75 | 3.84 | 3.84 |
| 202.22 | 1.09 | 1.09 |
| 466.31 | 2.11 | 2.11 |
| 407.56 | 4.89 | 4.89 |
| 300.31 | 3.11 | 3.11 |
| 267.74 | 3.58 | 3.58 |
| 213.24 | 1.59 | 1.59 |
| 468.42 | 4.24 | 4.24 |
| 413.84 | 5.33 | 5.33 |
| 390.83 | 2.92 | 2.92 |
| 316.20 | 4.19 | 4.19 |
| 306.43 | 4.77 | 4.77 |
| 307.14 | 3.69 | 3.69 |
| 388.26 | 3.75 | 3.75 |
| 262.72 | 4.12 | 4.12 |
| 313.44 | 4.35 | 4.35 |
| 361.45 | 3.65 | 3.65 |
| 305.79 | 3.69 | 3.69 |
| 397.45 | 3.22 | 3.22 |
| 390.38 | 1.64 | 1.64 |
| 266.68 | 2.41 | 2.41 |
| 335.27 | 0.79 | 0.79 |
| 239.27 | 3.50 | 3.50 |
| 280.28 | 3.32 | 3.32 |
| 308.39 | 2.85 | 2.85 |
| 369.40 | 2.84 | 2.84 |
| 320.78 | 4.30 | 4.30 |
| 372.26 | 3.33 | 3.33 |
| 291.38 | 1.90 | 1.90 |
| 295.34 | 0.15 | 0.15 |
| 337.37 | 2.20 | 2.20 |
| 342.42 | 3.02 | 3.02 |
| 296.44 | 1.86 | 1.86 |
| 274.28 | 1.69 | 1.69 |
| 307.38 | 1.38 | 1.38 |
| 325.32 | 1.86 | 1.86 |
| 357.84 | 4.34 | 4.34 |
| 282.30 | 3.06 | 3.06 |
| 305.43 | 3.39 | 3.39 |
| 216.24 | 1.34 | 1.34 |
| 376.48 | 3.11 | 3.11 |
| 265.34 | 4.04 | 4.04 |
| 297.38 | 4.27 | 4.27 |
| 304.15 | 3.17 | 3.17 |
| 262.31 | 2.90 | 2.90 |
| 348.41 | 4.39 | 4.39 |
| 207.27 | 2.13 | 2.13 |
| 363.28 | 3.89 | 3.89 |
| 396.54 | 3.27 | 3.27 |
| 295.30 | 2.36 | 2.36 |
| 320.36 | 3.76 | 3.76 |
| 325.23 | 3.41 | 3.41 |
| 319.74 | 3.37 | 3.37 |
| 300.32 | 0.58 | 0.58 |
| 333.37 | 1.50 | 1.50 |
| 478.60 | 4.79 | 4.79 |
| 256.26 | 3.31 | 3.31 |
| 397.88 | 2.99 | 2.99 |
| 383.45 | 5.05 | 5.05 |
| 308.82 | 4.57 | 4.57 |
| 294.24 | 2.15 | 2.15 |
| 419.46 | 3.99 | 3.99 |
| 250.37 | 1.71 | 1.71 |
| 352.40 | 1.06 | 1.06 |
| 269.28 | 4.16 | 4.16 |
| 402.53 | 1.41 | 1.41 |
| 341.42 | 3.94 | 3.94 |
| 346.43 | 2.76 | 2.76 |
| 254.26 | 3.59 | 3.59 |
| 319.34 | 2.62 | 2.62 |
| 394.34 | 3.63 | 3.63 |
| 268.29 | 3.90 | 3.90 |
| 296.15 | 4.26 | 4.26 |
| 363.40 | 0.18 | 0.18 |
| 458.52 | 2.50 | 2.50 |
| 394.25 | 3.89 | 3.89 |
| 279.37 | 2.41 | 2.41 |
| 269.28 | 1.44 | 1.44 |
| 338.41 | 2.75 | 2.75 |
| 274.34 | 3.31 | 3.31 |
| 406.49 | 1.68 | 1.68 |
| 272.38 | 3.26 | 3.26 |
| 257.12 | 3.27 | 3.27 |
| 354.43 | 3.53 | 3.53 |
| 332.47 | 4.52 | 4.52 |
| 357.32 | 2.59 | 2.59 |
| 263.32 | 2.52 | 2.52 |
| 253.21 | 2.02 | 2.02 |
| 296.33 | 2.99 | 2.99 |
| 292.34 | 2.20 | 2.20 |
| 368.48 | 2.49 | 2.49 |
| 334.17 | 1.25 | 1.25 |
| 356.33 | 2.08 | 2.08 |
| 330.37 | 1.87 | 1.87 |
| 261.72 | 2.19 | 2.19 |
| 313.36 | 1.69 | 1.69 |
| 433.35 | 2.46 | 2.46 |
| 272.26 | 1.81 | 1.81 |
| 275.71 | 4.04 | 4.04 |
| 381.48 | 4.19 | 4.19 |
| 197.24 | 0.29 | 0.29 |
| 386.50 | 3.60 | 3.60 |
| 299.33 | 2.78 | 2.78 |
| 205.17 | 0.61 | 0.61 |
| 299.29 | 2.40 | 2.40 |
| 258.32 | 2.77 | 2.77 |
| 315.41 | 3.65 | 3.65 |
| 271.32 | 4.09 | 4.09 |
| 425.87 | 2.47 | 2.47 |
| 387.44 | 1.70 | 1.70 |
| 253.31 | 3.02 | 3.02 |
| 335.38 | 2.15 | 2.15 |
| 302.40 | 1.85 | 1.85 |
| 335.16 | 2.23 | 2.23 |
| 364.24 | 3.96 | 3.96 |
| 413.35 | 2.05 | 2.05 |
| 318.33 | 3.27 | 3.27 |
| 252.73 | 3.74 | 3.74 |
| 371.43 | 4.25 | 4.25 |
| 330.37 | 2.53 | 2.53 |
| 278.31 | 4.97 | 4.97 |
| 260.30 | 2.27 | 2.27 |
| 270.12 | 3.58 | 3.58 |
| 325.44 | 4.36 | 4.36 |
| 287.78 | 4.60 | 4.60 |
| 351.45 | 3.93 | 3.93 |
| 320.78 | 2.71 | 2.71 |
| 325.48 | 3.73 | 3.73 |
| 249.34 | 3.22 | 3.22 |
| 317.69 | 2.90 | 2.90 |
| 256.30 | 2.19 | 2.19 |
| 291.78 | 1.29 | 1.29 |
| 400.54 | 3.75 | 3.75 |
| 303.32 | 3.63 | 3.63 |
| 282.30 | 3.49 | 3.49 |
| 502.52 | 2.93 | 2.93 |
| 366.37 | 4.78 | 4.78 |
| 317.14 | 4.13 | 4.13 |
| 444.49 | 2.30 | 2.30 |
| 285.17 | 2.28 | 2.28 |
| 234.30 | 2.99 | 2.99 |
| 529.65 | 3.43 | 3.43 |
| 266.30 | 3.72 | 3.72 |
| 534.72 | 3.25 | 3.25 |
| 328.76 | 2.73 | 2.73 |
| 270.33 | 2.96 | 2.96 |
| 521.67 | 3.56 | 3.56 |
| 331.21 | 4.26 | 4.26 |
| 309.32 | 2.03 | 2.03 |
| 404.65 | 5.37 | 5.37 |
| 362.39 | 3.52 | 3.52 |
| 332.43 | 3.28 | 3.28 |
| 246.35 | 2.64 | 2.64 |
| 489.37 | 2.56 | 2.56 |
| 469.92 | 4.98 | 4.98 |
| 418.50 | 1.94 | 1.94 |
| 309.33 | 2.01 | 2.01 |
| 358.39 | 1.51 | 1.51 |
| 412.63 | 5.15 | 5.15 |
| 364.45 | 2.64 | 2.64 |
| 286.29 | 2.09 | 2.09 |
| 371.32 | 2.39 | 2.39 |
| 315.40 | 2.59 | 2.59 |
| 343.45 | 3.60 | 3.60 |
| 498.97 | 3.58 | 3.58 |
| 415.33 | 4.86 | 4.86 |
| 324.38 | 2.54 | 2.54 |
| 410.48 | 0.86 | 0.86 |
| 408.44 | 0.35 | 0.35 |
| 246.27 | 1.30 | 1.30 |
| 379.64 | 1.28 | 1.28 |
| 313.28 | 2.07 | 2.07 |
| 322.17 | 1.73 | 1.73 |
| 344.31 | 4.51 | 4.51 |
| 267.35 | 4.23 | 4.23 |
| 283.36 | 3.30 | 3.30 |
| 303.80 | 3.48 | 3.48 |
| 269.35 | 2.75 | 2.75 |
| 281.27 | 2.74 | 2.74 |
| 369.42 | 4.31 | 4.31 |
| 277.33 | 3.78 | 3.78 |
| 326.36 | 3.03 | 3.03 |
| 353.42 | 3.26 | 3.26 |
| 293.41 | 3.15 | 3.15 |
| 260.32 | 2.52 | 2.52 |
| 236.27 | 3.62 | 3.62 |
| 271.28 | 3.05 | 3.05 |
| 280.29 | 2.74 | 2.74 |
| 294.31 | 3.26 | 3.26 |
| 295.32 | 3.38 | 3.38 |
| 321.43 | 2.65 | 2.65 |
| 403.81 | 4.55 | 4.55 |
| 324.41 | 3.26 | 3.26 |
| 299.35 | 3.05 | 3.05 |
| 317.18 | 4.38 | 4.38 |
| 300.32 | 2.35 | 2.35 |
| 381.34 | 2.82 | 2.82 |
| 259.31 | 1.82 | 1.82 |
| 280.29 | 2.71 | 2.71 |