Assay Report Card

Basic Information

ID: ALA1794528

Type: Functional

Description: PUBCHEM_BIOASSAY: Dose Response orthogonal assay utilizing the direct end-point detection of NADPH for uHTS small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504690, AID504696]

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
162.190.930.93
302.373.573.57
302.374.204.20
227.293.053.05
217.180.810.81
274.18
296.553.623.62
318.813.123.12
544.536.816.81
257.313.063.06
261.733.713.71
217.274.074.07
282.341.931.93
398.423.483.48
220.323.283.28
287.102.772.77
324.383.493.49
269.351.871.87
166.222.402.40
327.123.863.86
264.333.753.75
227.314.064.06
284.343.043.04
300.313.893.89
153.140.670.67
226.230.340.34
288.393.313.31
412.443.963.96
360.322.602.60
290.272.492.49
271.280.940.94
339.382.982.98
462.985.255.25
322.703.213.21
346.864.574.57
374.283.413.41
348.273.133.13
331.843.633.63
191.251.961.96
243.292.152.15
281.313.073.07
285.302.682.68
295.394.244.24
343.434.714.71
260.130.910.91
321.802.852.85
420.402.982.98
334.371.761.76
364.242.562.56
309.414.634.63
572.574.114.11
217.321.241.24
393.494.614.61
328.803.553.55
334.472.242.24
442.523.813.81
426.474.654.65
304.394.654.65
297.383.373.37
351.864.164.16
359.814.114.11
297.364.194.19
418.502.622.62
259.313.503.50
451.605.705.70
433.513.923.92
295.352.242.24
449.894.894.89
346.413.033.03
363.414.384.38
323.233.763.76
406.505.635.63
523.575.195.19
445.363.123.12
476.556.186.18
356.331.681.68
221.643.193.19
287.231.421.42
416.305.445.44
410.475.315.31
467.594.904.90
318.414.084.08
261.363.833.83
423.564.644.64
403.453.693.69
409.494.244.24
434.453.433.43
325.362.792.79
262.332.302.30
540.112.602.60
291.273.813.81
355.423.783.78
426.483.553.55
462.552.942.94
264.323.933.93
398.473.623.62
399.424.284.28
417.914.224.22
241.323.363.36
407.543.993.99
445.572.672.67
334.422.302.30
340.834.634.63
333.353.283.28
278.382.052.05
376.33
431.544.454.45
319.392.262.26
311.833.753.75
376.483.313.31
371.414.434.43
416.864.784.78
438.676.286.28
195.221.521.52
385.424.564.56
393.424.614.61
337.864.784.78
425.873.173.17
392.504.004.00
451.123.703.70
326.280.670.67
381.595.395.39
316.391.341.34
377.422.972.97
357.443.113.11
239.19-0.65-0.65
399.360.870.87
281.434.574.57
319.842.342.34
351.394.344.34
443.475.025.02
391.444.794.79
436.996.516.51
400.485.285.28
333.764.114.11
279.371.601.60
347.833.373.37
386.892.622.62
228.252.422.42
353.362.902.90
226.323.243.24
330.411.361.36
431.534.764.76
242.241.471.47
238.293.413.41
501.561.931.93
303.792.852.85
381.454.664.66
351.234.084.08
265.341.521.52
400.314.314.31
305.723.303.30
348.272.982.98
377.494.334.33
412.045.275.27
402.546.486.48
382.453.333.33
370.872.582.58
343.454.484.48
497.573.953.95
391.432.512.51
234.312.512.51
307.763.313.31
248.281.111.11
360.462.842.84
388.463.913.91
315.403.293.29
299.332.562.56
360.832.442.44
327.413.753.75
380.502.662.66
236.731.941.94
375.360.600.60
204.273.003.00
247.103.483.48
315.353.373.37
316.413.023.02
329.814.064.06
372.400.950.95
198.222.342.34
384.440.820.82
467.553.943.94
228.252.422.42
315.393.893.89
530.373.453.45
355.784.214.21
503.584.794.79
423.534.274.27
386.361.821.82
433.311.571.57
288.393.313.31
320.402.612.61
276.133.713.71
521.582.212.21
396.452.022.02
283.291.871.87
410.313.343.34
384.341.131.13
389.423.303.30
376.515.185.18
332.271.341.34
301.260.380.38
432.683.803.80
405.390.930.93
325.373.453.45
370.442.492.49
268.732.402.40
406.313.783.78
383.862.922.92
319.262.282.28
322.393.223.22
319.672.092.09
327.341.641.64
410.463.073.07
424.503.663.66
334.373.483.48
262.272.652.65
351.484.164.16
339.423.353.35
327.412.812.81
213.283.313.31
293.241.031.03
433.585.205.20
267.25-0.01-0.01
272.423.883.88
342.834.984.98
321.255.215.21
361.853.683.68
510.695.745.74
354.793.643.64
340.773.333.33
302.281.321.32
354.504.524.52
226.324.254.25
354.432.542.54
512.635.585.58
566.404.504.50
530.373.483.48
368.441.121.12
371.894.504.50
305.402.132.13
243.313.403.40
290.342.742.74
375.434.474.47
320.373.833.83
391.834.054.05
313.614.484.48
332.154.034.03
306.324.484.48
382.372.682.68
305.384.584.58
305.333.333.33
317.191.421.42
217.302.322.32
419.483.533.53
402.454.864.86
421.574.294.29
407.522.942.94
409.875.125.12
396.472.782.78
309.804.524.52
342.463.153.15
383.411.481.48
388.542.552.55
309.462.212.21
404.562.462.46
431.342.732.73
280.742.722.72
269.303.123.12
280.333.563.56
596.434.504.50
357.442.692.69
296.352.492.49
202.211.501.50
302.281.321.32
187.312.492.49
379.855.115.11
514.224.684.68
315.414.154.15
360.442.642.64
330.35-0.04-0.04
418.523.243.24
486.984.404.40
320.371.571.57
497.505.515.51
303.263.313.31
304.292.352.35
451.645.575.57
495.001.831.83
338.413.053.05
333.374.844.84
250.371.711.71
176.221.171.17
430.334.324.32
244.333.573.57
323.403.023.02
319.362.992.99
272.693.383.38
428.494.254.25
361.423.563.56
273.384.014.01
277.321.841.84
235.291.881.88
361.853.683.68
445.484.264.26
377.471.881.88
342.261.961.96
464.864.454.45
394.341.811.81
331.372.852.85
421.414.704.70
380.502.522.52
373.212.322.32
289.242.802.80
330.424.294.29
437.523.933.93
356.382.882.88
317.194.084.08
212.303.073.07
304.804.694.69
481.961.971.97
372.282.862.86
246.262.792.79
328.372.352.35
304.192.732.73
345.352.702.70
315.361.891.89
337.453.853.85
374.493.233.23
430.513.513.51
462.552.942.94
169.181.731.73
416.503.483.48
355.394.814.81
406.474.414.41
388.492.752.75
504.334.354.35
423.882.922.92
267.292.652.65
339.423.773.77
402.324.324.32
348.413.913.91
410.483.863.86
442.955.005.00
297.383.963.96
278.413.303.30
325.781.471.47
233.313.553.55
263.273.333.33
278.403.473.47
438.552.662.66
277.123.113.11
276.362.612.61
253.742.962.96
387.493.963.96
354.371.851.85
289.293.563.56
289.763.613.61
368.443.173.17
213.353.273.27
356.841.751.75
314.292.892.89
423.904.184.18
317.403.823.82
285.733.043.04
224.301.221.22
312.353.033.03
296.414.304.30
592.643.003.00
297.311.961.96
403.453.323.32
299.333.603.60
277.352.922.92
266.753.343.34
346.864.594.59
427.572.632.63
325.393.773.77
256.302.112.11
287.343.663.66
478.261.631.63
382.424.134.13
452.492.322.32
232.710.060.06
327.251.601.60
513.543.133.13
319.363.643.64
343.322.322.32
437.913.233.23
410.482.412.41
312.813.123.12
413.391.181.18
204.302.592.59
299.242.372.37
368.402.352.35
383.845.255.25
328.421.961.96
351.413.703.70
439.952.852.85
360.894.964.96
348.341.811.81
414.552.912.91
361.330.340.34
362.303.443.44
341.392.652.65
273.333.813.81
348.502.552.55
370.914.004.00
532.465.365.36
417.514.094.09
326.472.642.64
331.722.932.93
280.334.004.00
530.744.654.65
445.484.264.26
234.282.072.07
370.411.481.48
261.733.713.71
438.533.643.64
346.491.961.96
439.523.683.68
308.342.742.74
492.156.806.80
279.723.843.84
284.272.622.62
204.231.831.83
296.184.364.36
288.313.703.70
443.644.464.46
532.533.553.55
231.683.603.60
259.341.291.29
303.302.612.61
485.032.912.91
218.210.590.59
252.302.922.92
315.352.672.67
245.283.193.19
272.292.962.96
245.283.193.19
252.302.922.92
230.231.221.22
414.402.972.97
418.455.875.87
425.534.134.13
318.793.363.36
220.302.552.55
556.675.835.83
428.624.404.40
306.312.802.80
284.343.013.01
282.092.022.02
336.433.023.02
299.353.353.35
296.332.492.49
508.602.072.07
298.344.484.48
302.332.842.84
543.573.903.90
284.342.702.70
165.221.601.60
284.343.013.01
298.250.550.55
450.626.706.70
441.984.644.64
302.351.721.72
256.332.832.83
452.513.823.82
184.250.880.88
298.344.484.48
557.594.214.21
449.513.933.93
296.414.644.64
478.574.724.72
331.321.351.35
326.402.912.91
348.453.683.68
416.614.244.24
208.652.482.48
273.333.813.81
180.231.891.89
277.282.382.38
250.090.300.30
261.283.273.27
279.241.841.84
249.251.221.22
501.533.683.68
362.462.782.78
441.984.644.64
298.373.013.01
227.222.662.66
308.344.304.30
333.272.542.54
290.282.922.92
390.783.393.39
363.243.463.46
311.773.353.35
380.492.022.02
529.504.044.04
382.492.802.80
295.294.074.07
286.293.133.13
557.594.214.21
454.574.924.92
332.401.961.96
367.872.902.90
326.373.473.47
522.574.164.16
300.271.081.08
299.374.294.29
338.322.432.43
593.227.937.93
305.762.632.63
372.302.862.86
468.513.523.52
245.230.610.61
452.104.094.09
312.433.623.62
318.332.652.65
315.464.044.04
312.240.240.24
482.655.955.95
332.363.673.67
305.250.090.09
288.354.044.04
357.392.902.90
429.523.693.69
364.844.174.17
368.330.800.80
305.250.090.09
466.954.694.69
237.272.402.40
392.381.871.87
449.533.873.87
264.163.143.14
438.421.181.18
351.433.493.49
355.423.443.44
406.283.423.42
339.423.693.69
408.381.571.57
360.33-0.04-0.04
274.281.041.04
394.422.032.03
289.250.390.39
291.751.231.23
332.362.362.36
433.944.274.27
373.321.821.82
412.452.522.52
279.321.391.39
434.473.773.77
388.433.983.98
449.490.910.91
362.781.701.70
423.524.884.88
321.413.583.58
445.593.183.18
318.331.451.45
340.772.592.59
424.452.042.04
293.351.781.78
319.363.403.40
452.513.913.91
342.793.083.08
325.393.383.38
410.453.913.91
345.352.702.70
330.31-0.05-0.05
315.402.212.21
288.783.113.11
426.483.983.98
358.151.691.69
329.793.213.21
323.701.041.04
466.683.923.92
454.892.562.56
336.762.152.15
321.25-0.20-0.20
323.354.044.04
338.413.343.34
331.322.312.31
367.793.953.95
387.243.183.18
394.422.032.03
241.681.741.74
325.371.641.64
414.513.323.32