Basic Information
ID: ALA1794542
Type: Functional
Description: PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of estrogen receptor alpha signaling. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA1794542
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 357.79 | 3.93 | 3.93 |
| 441.55 | 4.37 | 4.37 |
| 391.56 | 6.86 | 6.86 |
| 268.36 | 4.83 | 4.83 |
| 333.45 | 3.93 | 3.93 |
| 270.24 | 2.58 | 2.58 |
| 248.72 | 2.52 | 2.52 |
| 300.44 | 5.60 | 5.60 |
| 253.28 | 1.37 | 1.37 |
| 270.24 | 2.58 | 2.58 |
| 394.42 | 3.70 | 3.70 |
| 254.24 | 2.87 | 2.87 |
| 212.20 | 1.37 | 1.37 |
| 280.45 | 5.88 | 5.88 |
| 182.19 | 0.07 | 0.07 |
| 387.52 | 5.70 | 5.70 |
| 387.52 | 5.70 | 5.70 |
| 853.92 | 3.74 | 3.74 |
| 406.91 | 6.61 | 6.61 |
| 305.50 | 3.20 | 3.20 |
| 314.47 | 4.72 | 4.72 |
| 110.11 | 1.10 | 1.10 |
| 300.44 | 5.60 | 5.60 |
| 133.19 | 1.33 | 1.33 |
| 399.44 | 2.87 | 2.87 |
| 369.59 | 4.84 | 4.84 |
| 352.77 | 2.81 | 2.81 |
| 151.16 | 1.35 | 1.35 |
| 301.34 | 3.60 | 3.60 |
| 354.49 | 6.50 | 6.50 |
| 282.34 | 3.32 | 3.32 |
| 106.12 | 1.50 | 1.50 |
| 253.27 | 0.83 | 0.83 |
| 254.24 | 2.87 | 2.87 |
| 766.96 | 3.09 | 3.09 |
| 502.77 | 7.28 | 7.28 |
| 241.29 | 3.75 | 3.75 |
| 182.17 | -3.59 | -3.59 |
| 320.43 | 5.17 | 5.17 |
| 290.45 | 3.96 | 3.96 |
| 608.69 | 4.17 | 4.17 |
| 268.22 | 3.10 | 3.10 |
| 269.13 | 4.00 | 4.00 |
| 356.06 | 5.86 | 5.86 |
| 563.65 | 6.00 | 6.00 |
| 394.32 | 4.13 | 4.13 |
| 136.20 | 1.33 | 1.33 |
| 505.46 | 4.18 | 4.18 |
| 372.81 | 4.41 | 4.41 |
| 361.78 | 4.60 | 4.60 |
| 147.09 | -0.68 | -0.68 |
| 180.21 | 2.78 | 2.78 |
| 471.50 | 6.34 | 6.34 |
| 270.24 | 1.89 | 1.89 |
| 270.24 | 1.37 | 1.37 |
| 289.55 | 5.14 | 5.14 |
| 305.21 | 1.93 | 1.93 |
| 215.89 | 4.30 | 4.30 |
| 198.14 | 0.19 | 0.19 |
| 1202.63 | ||
| 518.56 | 6.38 | 6.38 |
| 53.06 | 0.70 | 0.70 |
| 208.22 | 2.46 | 2.46 |
| 240.21 | 1.87 | 1.87 |
| 410.51 | 1.52 | 1.52 |
| 361.40 | 4.11 | 4.11 |
| 154.12 | -0.30 | -0.30 |
| 481.34 | 4.76 | 4.76 |
| 202.55 | 2.16 | 2.16 |
| 407.99 | 4.46 | 4.46 |
| 228.25 | 2.97 | 2.97 |
| 318.33 | 3.56 | 3.56 |
| 286.46 | 5.51 | 5.51 |
| 351.45 | 4.99 | 4.99 |
| 266.34 | 4.66 | 4.66 |
| 384.65 | 7.62 | 7.62 |
| 197.45 | 3.35 | 3.35 |
| 166.13 | 1.08 | 1.08 |
| 284.44 | 5.72 | 5.72 |
| 211.27 | 3.15 | 3.15 |
| 225.29 | 4.30 | 4.30 |
| 267.16 | 3.75 | 3.75 |
| 193.25 | 3.58 | 3.58 |
| 330.47 | 3.84 | 3.84 |
| 268.28 | 0.79 | 0.79 |
| 256.35 | 5.76 | 5.76 |
| 228.29 | 3.42 | 3.42 |
| 227.05 | 2.75 | 2.75 |
| 510.06 | 6.08 | 6.08 |
| 437.15 | 4.28 | 4.28 |
| 213.66 | 3.30 | 3.30 |
| 198.13 | 1.52 | 1.52 |
| 170.21 | 3.06 | 3.06 |
| 200.32 | 3.99 | 3.99 |
| 231.89 | 4.01 | 4.01 |
| 384.45 | 6.46 | 6.46 |
| 281.35 | 1.04 | 1.04 |
| 178.23 | 3.99 | 3.99 |
| 386.45 | 5.28 | 5.28 |
| 663.90 | 4.75 | 4.75 |
| 326.23 | 3.99 | 3.99 |
| 350.42 | 5.46 | 5.46 |
| 260.33 | 2.02 | 2.02 |
| 416.95 | 4.61 | 4.61 |
| 192.12 | -1.25 | -1.25 |
| 220.36 | 4.69 | 4.69 |
| 147.18 | 1.66 | 1.66 |
| 402.44 | 3.86 | 3.86 |
| 531.44 | 4.21 | 4.21 |
| 318.38 | 2.46 | 2.46 |
| 247.25 | 4.49 | 4.49 |
| 257.44 | 2.16 | 2.16 |
| 219.29 | 4.58 | 4.58 |
| 464.07 | 5.08 | 5.08 |
| 217.31 | 3.69 | 3.69 |
| 543.87 | 6.47 | 6.47 |
| 245.88 | 2.52 | 2.52 |
| 118.13 | 2.43 | 2.43 |
| 320.05 | 5.93 | 5.93 |
| 409.78 | 5.68 | 5.68 |
| 345.65 | 5.21 | 5.21 |
| 317.60 | 4.60 | 4.60 |
| 354.49 | 6.50 | 6.50 |
| 242.32 | 3.81 | 3.81 |
| 313.35 | 3.10 | 3.10 |
| 548.63 | 3.48 | 3.48 |
| 461.56 | 5.86 | 5.86 |
| 448.09 | 6.07 | 6.07 |
| 166.22 | 2.40 | 2.40 |
| 123.15 | 1.28 | 1.28 |
| 262.44 | 5.28 | 5.28 |
| 364.94 | 5.24 | 5.24 |
| 211.22 | 1.62 | 1.62 |
| 370.49 | 5.60 | 5.60 |
| 302.34 | 1.52 | 1.52 |
| 403.39 | 4.09 | 4.09 |
| 300.59 | 2.91 | 2.91 |
| 166.22 | 2.40 | 2.40 |
| 376.58 | 5.51 | 5.51 |
| 244.21 | -3.17 | -3.17 |
| 764.95 | 3.25 | 3.25 |
| 345.42 | 2.90 | 2.90 |
| 312.45 | 4.64 | 4.64 |
| 362.77 | 4.43 | 4.43 |
| 230.22 | 2.03 | 2.03 |
| 340.42 | 3.57 | 3.57 |
| 650.98 | 3.95 | 3.95 |
| 312.45 | 4.64 | 4.64 |
| 293.75 | 3.12 | 3.12 |
| 1255.44 | ||
| 350.59 | 4.72 | 4.72 |
| 494.48 | 6.38 | 6.38 |
| 340.51 | 5.90 | 5.90 |
| 404.82 | ||
| 625.56 | 4.18 | 4.18 |
| 563.99 | 1.03 | 1.03 |
| 387.82 | 4.24 | 4.24 |
| 317.33 | 2.00 | 2.00 |
| 297.27 | -2.63 | -2.63 |
| 490.64 | 4.62 | 4.62 |
| 370.92 | 2.47 | 2.47 |
| 408.92 | 2.17 | 2.17 |
| 334.52 | 4.60 | 4.60 |
| 318.37 | 3.58 | 3.58 |
| 287.17 | 4.56 | 4.56 |
| 385.48 | ||
| 367.04 | ||
| 306.36 | 4.16 | 4.16 |
| 322.40 | 3.29 | 3.29 |
| 265.31 | ||
| 579.99 | 0.00 | 0.00 |
| 1229.32 | ||
| 291.82 | 3.35 | 3.35 |
| 220.36 | 4.54 | 4.54 |
| 406.27 | 4.67 | 4.67 |
| 596.12 | ||
| 265.91 | 4.04 | 4.04 |
| 376.67 | 4.60 | 4.60 |
| 414.47 | 6.06 | 6.06 |
| 320.05 | 5.93 | 5.93 |
| 234.73 | 2.70 | 2.70 |
| 436.75 | 6.57 | 6.57 |
| 316.88 | 3.88 | 3.88 |
| 266.09 | -1.08 | -1.08 |
| 373.91 | 2.50 | 2.50 |
| 142.59 | 1.50 | 1.50 |
| 158.20 | 2.00 | 2.00 |
| 780.95 | 2.22 | 2.22 |
| 403.82 | 2.57 | 2.57 |
| 315.59 | 5.29 | 5.29 |
| 345.23 | 4.22 | 4.22 |
| 303.85 | ||
| 325.51 | ||
| 527.41 | 7.18 | 7.18 |
| 317.71 | 0.61 | 0.61 |
| 332.48 | 4.40 | 4.40 |
| 380.87 | 5.87 | 5.87 |
| 313.87 | 4.17 | 4.17 |
| 249.71 | 2.66 | 2.66 |
| 444.70 | 5.80 | 5.80 |
| 361.49 | 5.77 | 5.77 |
| 598.09 | 6.56 | 6.56 |
| 350.30 | 3.73 | 3.73 |
| 204.18 | 1.95 | 1.95 |
| 391.56 | 6.86 | 6.86 |
| 311.41 | 3.49 | 3.49 |
| 150.18 | 1.75 | 1.75 |
| 488.59 | 5.20 | 5.20 |
| 100.12 | 0.55 | 0.55 |
| 452.45 | 0.27 | 0.27 |
| 295.34 | 4.01 | 4.01 |
| 429.60 | 5.41 | 5.41 |
| 106.55 | 1.55 | 1.55 |
| 344.39 | 1.43 | 1.43 |
| 248.71 | 2.97 | 2.97 |
| 462.12 | 6.38 | 6.38 |
| 286.33 | 3.27 | 3.27 |
| 250.34 | 4.12 | 4.12 |
| 218.68 | 3.64 | 3.64 |
| 267.24 | 2.68 | 2.68 |
| 314.30 | 2.01 | 2.01 |
| 822.95 | 4.34 | 4.34 |
| 260.34 | 5.17 | 5.17 |
| 690.82 | 6.47 | 6.47 |
| 336.74 | ||
| 252.32 | 5.64 | 5.64 |
| 222.24 | 1.24 | 1.24 |
| 214.22 | 2.61 | 2.61 |
| 294.18 | ||
| 271.50 | ||
| 72.11 | 0.80 | 0.80 |
| 240.67 | 1.50 | 1.50 |
| 211.69 | 2.67 | 2.67 |
| 311.85 | 4.16 | 4.16 |
| 341.50 | 4.26 | 4.26 |
| 211.65 | 2.07 | 2.07 |
| 220.36 | 4.11 | 4.11 |
| 350.48 | 3.92 | 3.92 |
| 155.16 | 1.56 | 1.56 |
| 252.32 | 5.64 | 5.64 |
| 123.15 | 1.28 | 1.28 |
| 169.21 | -1.03 | -1.03 |
| 226.32 | 4.25 | 4.25 |
| 217.44 | 1.16 | 1.16 |
| 181.32 | 3.24 | 3.24 |
| 164.25 | 2.12 | 2.12 |
| 178.02 | 2.28 | 2.28 |
| 183.32 | ||
| 428.48 | 1.62 | 1.62 |
| 298.00 | ||
| 197.45 | 3.35 | 3.35 |
| 296.28 | 3.31 | 3.31 |
| 241.29 | 2.67 | 2.67 |
| 350.46 | 6.20 | 6.20 |
| 398.44 | 2.45 | 2.45 |
| 302.32 | 0.49 | 0.49 |
| 214.22 | 0.46 | 0.46 |
| 546.81 | 11.25 | 11.25 |
| 320.25 | 1.99 | 1.99 |
| 269.77 | 3.12 | 3.12 |
| 305.83 | 0.76 | 0.76 |
| 130.19 | 2.97 | 2.97 |
| 140.14 | 1.34 | 1.34 |
| 130.20 | 1.37 | 1.37 |
| 358.55 | 6.46 | 6.46 |
| 306.49 | 6.14 | 6.14 |
| 231.89 | 4.01 | 4.01 |
| 367.82 | 4.24 | 4.24 |
| 330.21 | 1.69 | 1.69 |
| 927.02 | 4.39 | 4.39 |
| 268.40 | 5.28 | 5.28 |
| 213.35 | 3.27 | 3.27 |
| 411.80 | 5.38 | 5.38 |
| 337.42 | 3.93 | 3.93 |
| 125.17 | 1.21 | 1.21 |
| 223.49 | 3.41 | 3.41 |
| 150.18 | 2.15 | 2.15 |
| 251.08 | ||
| 284.44 | 5.72 | 5.72 |
| 192.21 | 1.79 | 1.79 |
| 368.37 | 6.26 | 6.26 |
| 101.19 | 1.40 | 1.40 |
| 344.05 | 0.94 | 0.94 |
| 198.22 | 3.83 | 3.83 |
| 298.29 | 0.15 | 0.15 |
| 278.34 | 3.61 | 3.61 |
| 177.20 | 1.60 | 1.60 |
| 128.17 | 1.37 | 1.37 |
| 231.89 | 4.01 | 4.01 |
| 323.83 | 3.80 | 3.80 |
| 326.05 | 3.82 | 3.82 |
| 410.49 | 4.34 | 4.34 |
| 348.48 | 5.57 | 5.57 |
| 140.18 | 0.95 | 0.95 |
| 326.50 | 5.57 | 5.57 |
| 374.40 | 4.70 | 4.70 |
| 324.79 | 2.04 | 2.04 |
| 383.37 | 5.00 | 5.00 |
| 403.89 | 2.80 | 2.80 |
| 284.48 | 6.19 | 6.19 |
| 187.31 | 2.74 | 2.74 |
| 319.94 | 4.12 | 4.12 |
| 428.12 | 4.40 | 4.40 |
| 639.83 | 5.73 | 5.73 |
| 384.52 | 6.19 | 6.19 |
| 407.62 | 5.46 | 5.46 |
| 326.23 | 3.99 | 3.99 |
| 160.56 | 1.74 | 1.74 |
| 300.36 | 3.82 | 3.82 |
| 380.91 | 4.48 | 4.48 |
| 290.83 | 3.64 | 3.64 |
| 731.97 | 5.49 | 5.49 |
| 205.26 | 2.22 | 2.22 |
| 407.33 | 1.42 | 1.42 |
| 465.09 | 5.99 | 5.99 |
| 241.87 | 0.48 | 0.48 |
| 914.14 | 5.52 | 5.52 |
| 241.36 | 2.23 | 2.23 |
| 276.34 | 6.33 | 6.33 |
| 411.17 | ||
| 409.78 | 5.68 | 5.68 |
| 359.42 | 5.18 | 5.18 |
| 368.42 | 4.89 | 4.89 |
| 513.59 | 4.94 | 4.94 |
| 157.21 | 0.67 | 0.67 |
| 319.84 | 3.34 | 3.34 |
| 296.56 | 3.26 | 3.26 |
| 1008.26 | 5.60 | 5.60 |
| 422.03 | 2.92 | 2.92 |
| 338.19 | 2.30 | 2.30 |
| 263.90 | 4.61 | 4.61 |
| 514.08 | 5.72 | 5.72 |
| 185.23 | 3.14 | 3.14 |
| 345.39 | 2.78 | 2.78 |
| 255.21 | -0.23 | -0.23 |
| 380.78 | 3.65 | 3.65 |
| 308.46 | 4.22 | 4.22 |
| 542.71 | 4.92 | 4.92 |
| 253.09 | 2.09 | 2.09 |
| 385.18 | ||
| 728.78 | -1.51 | -1.51 |
| 375.73 | 4.49 | 4.49 |
| 305.45 | 4.18 | 4.18 |
| 247.68 | 3.30 | 3.30 |
| 249.09 | 3.24 | 3.24 |
| 461.15 | 5.47 | 5.47 |
| 240.22 | 2.72 | 2.72 |
| 349.07 | 3.52 | 3.52 |
| 242.06 | 3.24 | 3.24 |
| 214.35 | 4.08 | 4.08 |
| 411.33 | 5.94 | 5.94 |
| 351.85 | ||
| 401.83 | 1.32 | 1.32 |
| 333.86 | 3.86 | 3.86 |
| 408.38 | 4.17 | 4.17 |
| 314.22 | 3.66 | 3.66 |
| 336.23 | 4.51 | 4.51 |
| 178.23 | 0.05 | 0.05 |
| 577.93 | 6.58 | 6.58 |
| 322.43 | 5.55 | 5.55 |
| 527.84 | 4.09 | 4.09 |
| 458.83 | 4.56 | 4.56 |
| 290.06 | ||
| 389.32 | 4.45 | 4.45 |
| 334.87 | 3.60 | 3.60 |
| 224.15 | 1.48 | 1.48 |
| 254.41 | 5.03 | 5.03 |
| 260.68 | 2.64 | 2.64 |
| 697.61 | 5.62 | 5.62 |
| 347.00 | ||
| 285.80 | ||
| 602.81 | 4.17 | 4.17 |
| 1732.15 | ||
| 676.84 | 3.03 | 3.03 |