ID: ALA1794568
Type: Functional
Description: PUBCHEM_BIOASSAY: qHTS of small molecules that selectively kill Giardia lamblia: Hit Validation in HepG2 cytotox. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540272]
Organism: Giardia
Bioactivity
Activity Types for Assay ALA1794568
Potency
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
257.24 | 3.03 | 3.03 |
399.97 | 5.97 | 5.97 |
278.24 | 3.12 | 3.12 |
260.25 | 1.11 | 1.11 |
285.69 | -0.30 | -0.30 |
200.15 | -0.08 | -0.08 |
520.50 | 3.30 | 3.30 |
296.55 | 3.62 | 3.62 |
183.25 | 3.11 | 3.11 |
226.24 | 0.12 | 0.12 |
282.30 | 2.23 | 2.23 |
321.33 | -0.59 | -0.59 |
225.21 | 2.69 | 2.69 |
235.29 | 3.24 | 3.24 |
291.35 | 4.42 | 4.42 |
291.35 | 4.42 | 4.42 |
274.37 | 4.47 | 4.47 |
366.41 | 1.12 | 1.12 |
235.28 | 0.49 | 0.49 |
265.31 | 0.50 | 0.50 |
1101.28 | ||
546.53 | 5.09 | 5.09 |
233.18 | 1.84 | 1.84 |
290.32 | 2.89 | 2.89 |
262.22 | 2.45 | 2.45 |
238.24 | 2.25 | 2.25 |
233.18 | 1.84 | 1.84 |
317.30 | 2.28 | 2.28 |
326.35 | 3.59 | 3.59 |
299.24 | 2.02 | 2.02 |
268.27 | 3.17 | 3.17 |
358.37 | 2.32 | 2.32 |
275.29 | 2.42 | 2.42 |
438.53 | 4.66 | 4.66 |
418.49 | 4.28 | 4.28 |
272.30 | 2.66 | 2.66 |
270.72 | 4.37 | 4.37 |
433.51 | 4.21 | 4.21 |
418.40 | 0.28 | 0.28 |
348.36 | -1.31 | -1.31 |
297.35 | 0.16 | 0.16 |
289.32 | 2.73 | 2.73 |
266.26 | 2.01 | 2.01 |
462.98 | 5.25 | 5.25 |
307.40 | 3.13 | 3.13 |
429.95 | 3.17 | 3.17 |
399.54 | 3.53 | 3.53 |
360.64 | 5.10 | 5.10 |
360.64 | 5.10 | 5.10 |
360.64 | 5.10 | 5.10 |
339.39 | 0.73 | 0.73 |
265.31 | 0.50 | 0.50 |
395.41 | 2.78 | 2.78 |
290.37 | 3.94 | 3.94 |
337.38 | 3.24 | 3.24 |
207.19 | -1.32 | -1.32 |
456.46 | 7.63 | 7.63 |
489.65 | 4.64 | 4.64 |
309.33 | 1.03 | 1.03 |
410.43 | 1.58 | 1.58 |
284.27 | 2.54 | 2.54 |
356.37 | 3.38 | 3.38 |
266.23 | 2.07 | 2.07 |
255.28 | 2.37 | 2.37 |
228.21 | -2.14 | -2.14 |
276.34 | 3.70 | 3.70 |
234.25 | -0.71 | -0.71 |
371.33 | 4.42 | 4.42 |
260.21 | 2.40 | 2.40 |
387.87 | 3.12 | 3.12 |
340.45 | 5.33 | 5.33 |
223.23 | 2.70 | 2.70 |
333.39 | 3.54 | 3.54 |
223.28 | 3.01 | 3.01 |
329.38 | 3.84 | 3.84 |
271.71 | 3.47 | 3.47 |
329.38 | 2.23 | 2.23 |
262.32 | 2.98 | 2.98 |
309.35 | 4.14 | 4.14 |
240.20 | 1.95 | 1.95 |
277.35 | 4.12 | 4.12 |
454.87 | 4.06 | 4.06 |
334.44 | 4.46 | 4.46 |
260.25 | 3.06 | 3.06 |
260.25 | 3.06 | 3.06 |
339.46 | 4.64 | 4.64 |
344.15 | 3.26 | 3.26 |
299.36 | 3.13 | 3.13 |
270.25 | -0.56 | -0.56 |
343.13 | 2.71 | 2.71 |
420.96 | 3.74 | 3.74 |
485.96 | 5.68 | 5.68 |
413.46 | 3.16 | 3.16 |
476.55 | 6.18 | 6.18 |
488.71 | 4.43 | 4.43 |
345.75 | 2.68 | 2.68 |
326.72 | 2.18 | 2.18 |
254.24 | 2.57 | 2.57 |
478.64 | 3.95 | 3.95 |
235.25 | -0.67 | -0.67 |
283.29 | 0.87 | 0.87 |
295.25 | 1.33 | 1.33 |
315.33 | 3.43 | 3.43 |
576.71 | 5.33 | 5.33 |
271.34 | 3.21 | 3.21 |
223.23 | 2.24 | 2.24 |
307.29 | 1.83 | 1.83 |
294.65 | 3.30 | 3.30 |
303.71 | 0.69 | 0.69 |
379.39 | 2.61 | 2.61 |
406.83 | 1.77 | 1.77 |
381.37 | 1.46 | 1.46 |
348.31 | 3.56 | 3.56 |
498.57 | 2.95 | 2.95 |
313.72 | 2.72 | 2.72 |
342.17 | 3.00 | 3.00 |
323.26 | 2.19 | 2.19 |
312.33 | 5.30 | 5.30 |
316.27 | 2.13 | 2.13 |
260.25 | 3.06 | 3.06 |
385.38 | 2.09 | 2.09 |
275.76 | 3.86 | 3.86 |
254.21 | 0.14 | 0.14 |
490.59 | 5.01 | 5.01 |
256.21 | 2.06 | 2.06 |
318.13 | 3.67 | 3.67 |
318.40 | 4.53 | 4.53 |
306.37 | 3.43 | 3.43 |
440.57 | 4.27 | 4.27 |
369.38 | 3.62 | 3.62 |
343.41 | 3.02 | 3.02 |
385.38 | 1.31 | 1.31 |
246.22 | 2.75 | 2.75 |
338.36 | 4.40 | 4.40 |
277.31 | 2.62 | 2.62 |
427.29 | 4.04 | 4.04 |
325.25 | 3.33 | 3.33 |
538.27 | 2.65 | 2.65 |
434.50 | 3.25 | 3.25 |
468.39 | 2.07 | 2.07 |
316.57 | 3.41 | 3.41 |
338.46 | 3.47 | 3.47 |
373.37 | 4.37 | 4.37 |
265.32 | 3.38 | 3.38 |
364.45 | 1.74 | 1.74 |
386.41 | 2.89 | 2.89 |
420.85 | 3.40 | 3.40 |
271.27 | 3.65 | 3.65 |
409.42 | 2.62 | 2.62 |
204.19 | 1.69 | 1.69 |
410.52 | 4.75 | 4.75 |
330.21 | 2.82 | 2.82 |
284.27 | 2.72 | 2.72 |
297.32 | 0.83 | 0.83 |
488.71 | 4.43 | 4.43 |
267.29 | 2.82 | 2.82 |
247.21 | 1.51 | 1.51 |
386.41 | 2.74 | 2.74 |
319.36 | 2.19 | 2.19 |
354.16 | 2.72 | 2.72 |
335.34 | 2.48 | 2.48 |
288.22 | 1.64 | 1.64 |
281.27 | 3.38 | 3.38 |
234.33 | 2.31 | 2.31 |
374.45 | 2.79 | 2.79 |
275.76 | 3.86 | 3.86 |
266.32 | 2.68 | 2.68 |
411.25 | 2.42 | 2.42 |
386.41 | 2.74 | 2.74 |
335.75 | 3.69 | 3.69 |
256.31 | 3.39 | 3.39 |
394.41 | 1.52 | 1.52 |
323.31 | 3.67 | 3.67 |
485.16 | 3.97 | 3.97 |
320.29 | 2.61 | 2.61 |
420.43 | 3.40 | 3.40 |
474.41 | 5.39 | 5.39 |
306.26 | 2.55 | 2.55 |
312.32 | 3.66 | 3.66 |
230.29 | 3.07 | 3.07 |
283.28 | 2.55 | 2.55 |
327.32 | 0.16 | 0.16 |
293.26 | 2.03 | 2.03 |
360.35 | 2.28 | 2.28 |
385.76 | 4.35 | 4.35 |
291.74 | 2.37 | 2.37 |
376.78 | 4.19 | 4.19 |
394.44 | 2.49 | 2.49 |
335.12 | 3.64 | 3.64 |
363.46 | 2.68 | 2.68 |
341.28 | 3.29 | 3.29 |
299.33 | 2.56 | 2.56 |
365.82 | 3.68 | 3.68 |
454.91 | 3.74 | 3.74 |
306.24 | 3.04 | 3.04 |
314.30 | 2.90 | 2.90 |
269.31 | 1.73 | 1.73 |
281.25 | 1.60 | 1.60 |
387.37 | 3.76 | 3.76 |
458.45 | 3.42 | 3.42 |
347.33 | 1.54 | 1.54 |
220.36 | 4.11 | 4.11 |
283.36 | 3.41 | 3.41 |
395.50 | 4.28 | 4.28 |
320.35 | 3.17 | 3.17 |
279.35 | 2.72 | 2.72 |
353.24 | 2.33 | 2.33 |
527.60 | 4.78 | 4.78 |
436.44 | 2.65 | 2.65 |
350.29 | 3.64 | 3.64 |
446.89 | 5.00 | 5.00 |
236.27 | 1.13 | 1.13 |
429.88 | 3.05 | 3.05 |
311.41 | 3.92 | 3.92 |
247.32 | 2.04 | 2.04 |
246.22 | 2.75 | 2.75 |
323.74 | 2.57 | 2.57 |
384.13 | ||
495.59 | 4.32 | 4.32 |
361.32 | 3.15 | 3.15 |
338.32 | 2.90 | 2.90 |
287.25 | 0.18 | 0.18 |
298.32 | 4.06 | 4.06 |
456.49 | 3.80 | 3.80 |
306.27 | 0.23 | 0.23 |
343.86 | 3.64 | 3.64 |
360.28 | 2.51 | 2.51 |
303.32 | 2.41 | 2.41 |
283.24 | 2.99 | 2.99 |
415.53 | 4.40 | 4.40 |
383.45 | 4.24 | 4.24 |
324.13 | 3.07 | 3.07 |
283.29 | 0.35 | 0.35 |
219.63 | 0.70 | 0.70 |
393.78 | 3.19 | 3.19 |
283.29 | 0.35 | 0.35 |
304.29 | 2.75 | 2.75 |
362.46 | 4.34 | 4.34 |
310.27 | 3.44 | 3.44 |
322.41 | 3.95 | 3.95 |
375.34 | 3.76 | 3.76 |
375.72 | 3.94 | 3.94 |
415.36 | 1.95 | 1.95 |
402.62 | 4.17 | 4.17 |
362.32 | 1.31 | 1.31 |
315.24 | 2.29 | 2.29 |
341.37 | 1.85 | 1.85 |
264.27 | 2.70 | 2.70 |
318.37 | 3.52 | 3.52 |
236.27 | 3.42 | 3.42 |
299.29 | 1.96 | 1.96 |
340.34 | 2.98 | 2.98 |
460.53 | 5.27 | 5.27 |
468.56 | 4.31 | 4.31 |
416.48 | 3.99 | 3.99 |
294.38 | 3.17 | 3.17 |
298.30 | 2.23 | 2.23 |
388.25 | 3.92 | 3.92 |
324.71 | 3.10 | 3.10 |
277.70 | ||
235.25 | 0.12 | 0.12 |
259.26 | 2.61 | 2.61 |
252.29 | 2.29 | 2.29 |
460.80 | 3.45 | 3.45 |
287.30 | 2.42 | 2.42 |
321.34 | 3.63 | 3.63 |
252.19 | 0.45 | 0.45 |
213.20 | -0.44 | -0.44 |
341.32 | 2.45 | 2.45 |
273.29 | 3.40 | 3.40 |
416.48 | 5.02 | 5.02 |
276.30 | 2.57 | 2.57 |
249.25 | 2.30 | 2.30 |
332.25 | 1.23 | 1.23 |
294.25 | 2.21 | 2.21 |
336.37 | 2.51 | 2.51 |
214.18 | 0.20 | 0.20 |
309.33 | 1.64 | 1.64 |
267.33 | 2.61 | 2.61 |
320.31 | 2.36 | 2.36 |
260.25 | 3.06 | 3.06 |
309.12 | 2.57 | 2.57 |
231.21 | 2.46 | 2.46 |
307.33 | 2.85 | 2.85 |
380.79 | 1.49 | 1.49 |
250.25 | 1.63 | 1.63 |
301.73 | 3.37 | 3.37 |
309.37 | 3.57 | 3.57 |
277.37 | 2.58 | 2.58 |
537.69 | 4.13 | 4.13 |
268.27 | 2.46 | 2.46 |
283.36 | 3.31 | 3.31 |
399.36 | 1.81 | 1.81 |
321.25 | 1.57 | 1.57 |
313.38 | 3.55 | 3.55 |
402.79 | 2.33 | 2.33 |
388.41 | 2.77 | 2.77 |
299.29 | 0.05 | 0.05 |
364.27 | 2.85 | 2.85 |
406.83 | 3.15 | 3.15 |
271.30 | 3.86 | 3.86 |
366.49 | 4.22 | 4.22 |
305.21 | 2.55 | 2.55 |
357.41 | 0.63 | 0.63 |
407.56 | 4.28 | 4.28 |
350.29 | 3.64 | 3.64 |
328.28 | 3.11 | 3.11 |
350.29 | 3.64 | 3.64 |
303.32 | 3.85 | 3.85 |
491.39 | 3.18 | 3.18 |
279.30 | 0.85 | 0.85 |
270.25 | -0.56 | -0.56 |
398.38 | 1.69 | 1.69 |
398.90 | 2.39 | 2.39 |
269.26 | 0.04 | 0.04 |
355.31 | 3.59 | 3.59 |
350.84 | 2.29 | 2.29 |
434.45 | 3.71 | 3.71 |
274.23 | 2.64 | 2.64 |
163.14 | 1.24 | 1.24 |
338.41 | 3.07 | 3.07 |
512.56 | 4.25 | 4.25 |
395.39 | 1.77 | 1.77 |
347.37 | 2.35 | 2.35 |
262.22 | 2.45 | 2.45 |
329.34 | 3.87 | 3.87 |
482.76 | 5.96 | 5.96 |
445.57 | 4.40 | 4.40 |
424.43 | 3.90 | 3.90 |
305.21 | 2.55 | 2.55 |
347.31 | 2.82 | 2.82 |
332.45 | 4.97 | 4.97 |
501.61 | 4.78 | 4.78 |
319.36 | 4.34 | 4.34 |
325.32 | 1.84 | 1.84 |
258.31 | 2.35 | 2.35 |
324.34 | 2.99 | 2.99 |
328.15 | 3.07 | 3.07 |
392.32 | 2.56 | 2.56 |
312.31 | 3.48 | 3.48 |
400.44 | 3.13 | 3.13 |
535.05 | 4.79 | 4.79 |
483.71 | 3.76 | 3.76 |
239.28 | 2.95 | 2.95 |
342.44 | 3.79 | 3.79 |
256.26 | 2.37 | 2.37 |
482.54 | 1.77 | 1.77 |
372.38 | 2.50 | 2.50 |
376.14 | 2.20 | 2.20 |
312.08 | 2.60 | 2.60 |
291.33 | 3.18 | 3.18 |
263.28 | 2.61 | 2.61 |
264.67 | 2.46 | 2.46 |
373.39 | 1.88 | 1.88 |
330.32 | 3.27 | 3.27 |
572.62 | 5.66 | 5.66 |
263.28 | 2.61 | 2.61 |
296.24 | 3.01 | 3.01 |
374.35 | 3.05 | 3.05 |
372.43 | 3.70 | 3.70 |
198.18 | 1.19 | 1.19 |
371.31 | 3.29 | 3.29 |
364.32 | 3.95 | 3.95 |
253.26 | 3.39 | 3.39 |
311.35 | 1.09 | 1.09 |
257.31 | 3.71 | 3.71 |
411.46 | 1.82 | 1.82 |
392.80 | 2.76 | 2.76 |
408.46 | 2.80 | 2.80 |
317.33 | 2.00 | 2.00 |
367.11 | 4.13 | 4.13 |
396.49 | 2.12 | 2.12 |
472.57 | 4.41 | 4.41 |
271.35 | 3.21 | 3.21 |
323.31 | 3.43 | 3.43 |
309.37 | 4.25 | 4.25 |
273.34 | 2.24 | 2.24 |
303.30 | 2.86 | 2.86 |
323.33 | 3.97 | 3.97 |
326.34 | 3.49 | 3.49 |
269.30 | 3.02 | 3.02 |
287.32 | 2.51 | 2.51 |
328.74 | 2.50 | 2.50 |
487.58 | 2.41 | 2.41 |
318.38 | 3.18 | 3.18 |
399.41 | 2.39 | 2.39 |
263.28 | 2.61 | 2.61 |
283.36 | 3.49 | 3.49 |
266.30 | 3.43 | 3.43 |
355.42 | 4.14 | 4.14 |
342.32 | 1.71 | 1.71 |
282.25 | 3.59 | 3.59 |
319.30 | 3.06 | 3.06 |
364.37 | 3.88 | 3.88 |
357.35 | 3.75 | 3.75 |
366.44 | 2.35 | 2.35 |
351.75 | 2.93 | 2.93 |
488.71 | 4.73 | 4.73 |
297.32 | 0.83 | 0.83 |
255.35 | 3.51 | 3.51 |
364.32 | 3.95 | 3.95 |
336.39 | 3.59 | 3.59 |
378.82 | 3.24 | 3.24 |
364.79 | 2.85 | 2.85 |
359.36 | 1.49 | 1.49 |
260.25 | 2.01 | 2.01 |
355.40 | 1.99 | 1.99 |
266.64 | 3.09 | 3.09 |
401.44 | 2.39 | 2.39 |
258.30 | 3.07 | 3.07 |
481.00 | 3.99 | 3.99 |
143.01 | 1.48 | 1.48 |
238.24 | 2.20 | 2.20 |
274.28 | 2.05 | 2.05 |
288.31 | 3.70 | 3.70 |
518.56 | 1.14 | 1.14 |
548.59 | 1.15 | 1.15 |
325.68 | 2.80 | 2.80 |
273.29 | 3.40 | 3.40 |
467.56 | 1.43 | 1.43 |
414.53 | 3.57 | 3.57 |
330.34 | 3.07 | 3.07 |
296.75 | 2.34 | 2.34 |
428.84 | 3.90 | 3.90 |
312.72 | 2.38 | 2.38 |
427.46 | 1.42 | 1.42 |
434.51 | 2.70 | 2.70 |
280.29 | 1.36 | 1.36 |
398.50 | 2.44 | 2.44 |
333.37 | 2.75 | 2.75 |
370.58 | 4.40 | 4.40 |
436.49 | 3.07 | 3.07 |
285.37 | 4.00 | 4.00 |
438.89 | 2.99 | 2.99 |
399.19 | 3.36 | 3.36 |
258.32 | 3.53 | 3.53 |
428.34 | 3.11 | 3.11 |
278.31 | 2.74 | 2.74 |
253.35 | 3.44 | 3.44 |
452.25 | 2.57 | 2.57 |
317.26 | 1.61 | 1.61 |
365.37 | 2.22 | 2.22 |
399.81 | 2.13 | 2.13 |
271.32 | 3.53 | 3.53 |
238.25 | 1.87 | 1.87 |
353.34 | 1.63 | 1.63 |
241.23 | 1.69 | 1.69 |
412.97 | 4.97 | 4.97 |
338.32 | 2.43 | 2.43 |
253.26 | 2.22 | 2.22 |
289.25 | 1.72 | 1.72 |
625.76 | 5.05 | 5.05 |
274.23 | 2.64 | 2.64 |
354.44 | 2.60 | 2.60 |
386.43 | 1.84 | 1.84 |
411.50 | 4.62 | 4.62 |
231.25 | 1.58 | 1.58 |
290.37 | 3.71 | 3.71 |
473.55 | 1.10 | 1.10 |
316.40 | 4.24 | 4.24 |
351.24 | 3.50 | 3.50 |
281.34 | 4.20 | 4.20 |
246.31 | 3.99 | 3.99 |
144.18 | 1.94 | 1.94 |
145.18 | 1.06 | 1.06 |
291.40 | 3.06 | 3.06 |
461.52 | 3.64 | 3.64 |
343.43 | 1.97 | 1.97 |
193.16 | 0.96 | 0.96 |
346.22 | 4.74 | 4.74 |
425.48 | 5.25 | 5.25 |
314.82 | 4.22 | 4.22 |
366.46 | 1.38 | 1.38 |
276.30 | 3.53 | 3.53 |
289.38 | 4.05 | 4.05 |
378.49 | 5.12 | 5.12 |
461.61 | 4.71 | 4.71 |
312.37 | 3.77 | 3.77 |
306.39 | 3.85 | 3.85 |
444.43 | 2.76 | 2.76 |
337.38 | 3.71 | 3.71 |
462.47 | 5.83 | 5.83 |
447.47 | 2.28 | 2.28 |
295.77 | 4.64 | 4.64 |
349.76 | 3.82 | 3.82 |
236.27 | 2.77 | 2.77 |
349.30 | 3.85 | 3.85 |
287.30 | 2.47 | 2.47 |
465.26 | 4.93 | 4.93 |
265.27 | 0.97 | 0.97 |
375.26 | 4.28 | 4.28 |
288.26 | 1.75 | 1.75 |
289.32 | 2.73 | 2.73 |
316.70 | 3.84 | 3.84 |
339.76 | 3.08 | 3.08 |
317.30 | 2.33 | 2.33 |
367.41 | 5.22 | 5.22 |
428.45 | 5.12 | 5.12 |
299.24 | 2.70 | 2.70 |
326.40 | 3.55 | 3.55 |
322.25 | 1.96 | 1.96 |
295.33 | 1.44 | 1.44 |
355.35 | 3.87 | 3.87 |
286.32 | 3.20 | 3.20 |
279.28 | 1.45 | 1.45 |
235.27 | 1.39 | 1.39 |
324.30 | 2.74 | 2.74 |
302.29 | 2.06 | 2.06 |
300.34 | 3.51 | 3.51 |
320.40 | 3.29 | 3.29 |
305.38 | 4.31 | 4.31 |
445.56 | 4.30 | 4.30 |
345.36 | 3.06 | 3.06 |
293.31 | 1.31 | 1.31 |
395.01 | 2.53 | 2.53 |
353.23 | 5.47 | 5.47 |
303.27 | 2.03 | 2.03 |
321.36 | 2.44 | 2.44 |
309.80 | 4.95 | 4.95 |
289.32 | 2.35 | 2.35 |
277.24 | 2.16 | 2.16 |
318.36 | 2.53 | 2.53 |
390.36 | 4.07 | 4.07 |
276.28 | 1.82 | 1.82 |
289.25 | 1.37 | 1.37 |
373.35 | 1.84 | 1.84 |
343.30 | 1.59 | 1.59 |
318.25 | 1.79 | 1.79 |
295.35 | 2.41 | 2.41 |
251.24 | 1.83 | 1.83 |
287.32 | 1.70 | 1.70 |
465.49 | 2.41 | 2.41 |
340.36 | 3.28 | 3.28 |
333.32 | 1.95 | 1.95 |
354.19 | 3.18 | 3.18 |
331.37 | 3.24 | 3.24 |
313.27 | 1.91 | 1.91 |
309.34 | 4.14 | 4.14 |
270.32 | 1.77 | 1.77 |
303.23 | 1.68 | 1.68 |
355.17 | 2.58 | 2.58 |
303.27 | 2.03 | 2.03 |
320.31 | 1.68 | 1.68 |
253.24 | 1.33 | 1.33 |
401.38 | 3.80 | 3.80 |
345.42 | 2.29 | 2.29 |
328.44 | 4.11 | 4.11 |
483.55 | 3.06 | 3.06 |
435.83 | 4.46 | 4.46 |
305.31 | 1.84 | 1.84 |