Basic Information
ID: ALA1794575
Type: Functional
Description: PUBCHEM_BIOASSAY: MITF: Counter assay: A375 proliferation Measured in Cell-Based System Using Plate Reader - 2084-03_Inhibitor_Dose_CherryPick_Activity_Set2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488944]
Organism: Homo sapiens
Cell type: A-375
Activity Charts
Bioactivity
Activity Types for Assay ALA1794575
AC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 327.39 | 5.09 | 5.09 |
| 323.36 | 1.51 | 1.51 |
| 288.31 | 3.36 | 3.36 |
| 324.38 | 3.49 | 3.49 |
| 283.71 | 3.63 | 3.63 |
| 365.39 | 2.71 | 2.71 |
| 307.40 | 3.13 | 3.13 |
| 344.54 | 3.83 | 3.83 |
| 441.02 | 5.14 | 5.14 |
| 244.30 | 2.37 | 2.37 |
| 290.32 | 3.66 | 3.66 |
| 284.27 | 2.54 | 2.54 |
| 300.37 | 4.45 | 4.45 |
| 481.35 | 4.07 | 4.07 |
| 336.39 | 3.56 | 3.56 |
| 241.08 | 2.54 | 2.54 |
| 414.98 | 3.52 | 3.52 |
| 309.41 | 3.76 | 3.76 |
| 319.77 | 3.34 | 3.34 |
| 406.79 | 5.06 | 5.06 |
| 349.83 | 3.12 | 3.12 |
| 383.32 | 3.28 | 3.28 |
| 279.34 | 3.51 | 3.51 |
| 473.23 | 4.43 | 4.43 |
| 440.32 | 4.41 | 4.41 |
| 271.75 | 3.69 | 3.69 |
| 476.53 | 4.00 | 4.00 |
| 279.73 | 2.22 | 2.22 |
| 458.97 | 4.21 | 4.21 |
| 311.37 | 3.50 | 3.50 |
| 254.24 | 2.57 | 2.57 |
| 317.26 | 2.70 | 2.70 |
| 428.34 | 4.81 | 4.81 |
| 416.78 | 5.61 | 5.61 |
| 464.64 | 3.84 | 3.84 |
| 424.50 | 3.61 | 3.61 |
| 362.47 | 4.64 | 4.64 |
| 343.38 | 3.91 | 3.91 |
| 350.37 | 3.63 | 3.63 |
| 397.82 | 3.25 | 3.25 |
| 336.35 | 3.12 | 3.12 |
| 303.16 | 3.65 | 3.65 |
| 334.34 | 3.99 | 3.99 |
| 324.17 | 2.14 | 2.14 |
| 307.31 | 3.45 | 3.45 |
| 238.29 | 2.79 | 2.79 |
| 383.40 | 5.58 | 5.58 |
| 397.43 | 1.85 | 1.85 |
| 279.68 | 2.96 | 2.96 |
| 272.30 | 3.13 | 3.13 |
| 439.40 | 4.67 | 4.67 |
| 519.91 | 5.90 | 5.90 |
| 304.31 | 3.27 | 3.27 |
| 387.48 | 4.54 | 4.54 |
| 281.36 | 3.22 | 3.22 |
| 422.96 | 5.09 | 5.09 |
| 341.19 | 3.56 | 3.56 |
| 450.29 | 5.40 | 5.40 |
| 404.35 | 4.11 | 4.11 |
| 333.44 | 2.74 | 2.74 |
| 348.43 | 4.03 | 4.03 |
| 322.39 | 1.42 | 1.42 |
| 280.33 | 3.68 | 3.68 |
| 352.03 | 2.38 | 2.38 |
| 487.42 | 3.93 | 3.93 |
| 266.35 | 2.46 | 2.46 |
| 245.35 | 2.57 | 2.57 |
| 344.40 | 3.17 | 3.17 |
| 374.23 | 4.31 | 4.31 |
| 297.74 | 3.94 | 3.94 |
| 407.54 | 3.91 | 3.91 |
| 283.33 | 3.37 | 3.37 |
| 342.83 | 4.38 | 4.38 |
| 513.48 | 4.12 | 4.12 |
| 379.48 | 5.15 | 5.15 |
| 449.53 | 2.98 | 2.98 |
| 438.40 | 4.46 | 4.46 |
| 251.76 | 3.59 | 3.59 |
| 322.32 | 2.50 | 2.50 |
| 420.00 | 4.68 | 4.68 |
| 337.42 | 2.76 | 2.76 |
| 373.43 | 1.65 | 1.65 |
| 403.51 | 4.85 | 4.85 |
| 472.37 | 4.70 | 4.70 |
| 519.44 | 5.04 | 5.04 |
| 365.47 | 4.49 | 4.49 |
| 489.53 | 3.30 | 3.30 |
| 475.46 | 5.79 | 5.79 |
| 423.95 | 4.34 | 4.34 |
| 358.83 | 3.57 | 3.57 |
| 404.81 | 3.16 | 3.16 |
| 404.45 | 3.54 | 3.54 |
| 360.46 | 3.95 | 3.95 |
| 508.32 | 5.99 | 5.99 |
| 378.45 | 2.50 | 2.50 |
| 308.29 | 2.50 | 2.50 |
| 287.77 | 1.45 | 1.45 |
| 447.02 | 4.40 | 4.40 |
| 293.28 | 3.30 | 3.30 |
| 488.20 | 5.36 | 5.36 |
| 448.49 | 6.21 | 6.21 |
| 364.41 | 3.17 | 3.17 |
| 336.35 | 3.06 | 3.06 |
| 375.51 | 5.49 | 5.49 |
| 443.02 | 4.17 | 4.17 |
| 273.09 | 2.74 | 2.74 |
| 322.32 | 2.60 | 2.60 |
| 425.96 | 4.59 | 4.59 |
| 439.54 | 2.20 | 2.20 |
| 459.01 | 5.28 | 5.28 |
| 369.89 | 4.35 | 4.35 |
| 425.36 | 5.93 | 5.93 |
| 273.38 | 3.53 | 3.53 |
| 380.58 | 5.01 | 5.01 |
| 315.84 | 3.75 | 3.75 |
| 339.40 | 3.75 | 3.75 |
| 297.22 | 1.64 | 1.64 |
| 444.04 | 5.08 | 5.08 |
| 373.92 | 4.54 | 4.54 |
| 318.17 | 3.06 | 3.06 |
| 443.39 | 4.57 | 4.57 |
| 485.07 | 5.36 | 5.36 |
| 376.43 | 4.50 | 4.50 |
| 404.37 | 3.86 | 3.86 |
| 237.31 | 3.29 | 3.29 |
| 294.40 | 3.43 | 3.43 |
| 259.29 | 3.55 | 3.55 |
| 289.36 | 2.04 | 2.04 |
| 262.19 | -0.33 | -0.33 |
| 311.34 | 3.51 | 3.51 |
| 396.45 | 3.05 | 3.05 |
| 276.34 | 3.90 | 3.90 |
| 448.97 | 3.53 | 3.53 |
| 403.51 | 4.67 | 4.67 |
| 273.31 | 3.52 | 3.52 |
| 257.29 | 2.72 | 2.72 |
| 313.34 | 3.15 | 3.15 |
| 237.26 | 3.11 | 3.11 |
| 290.37 | 3.94 | 3.94 |
| 330.37 | 2.88 | 2.88 |
| 249.32 | 3.21 | 3.21 |
| 227.27 | 1.30 | 1.30 |
| 361.81 | 2.94 | 2.94 |
| 376.45 | 2.49 | 2.49 |
| 322.32 | 2.81 | 2.81 |
| 482.88 | 4.98 | 4.98 |
| 471.03 | 4.72 | 4.72 |
| 541.63 | 2.65 | 2.65 |
| 332.38 | 2.91 | 2.91 |
| 298.37 | 3.34 | 3.34 |
| 459.91 | 3.53 | 3.53 |
| 262.70 | 3.48 | 3.48 |
| 355.73 | 3.37 | 3.37 |
| 246.27 | 2.26 | 2.26 |
| 313.28 | 3.29 | 3.29 |
| 286.25 | 1.47 | 1.47 |
| 307.81 | 3.26 | 3.26 |
| 501.45 | 4.52 | 4.52 |
| 564.47 | 5.39 | 5.39 |
| 293.33 | 4.50 | 4.50 |
| 363.48 | 5.71 | 5.71 |
| 318.42 | 3.94 | 3.94 |
| 405.84 | 3.50 | 3.50 |
| 484.50 | 5.80 | 5.80 |
| 329.38 | 3.35 | 3.35 |
| 444.36 | 4.06 | 4.06 |
| 438.02 | 4.28 | 4.28 |
| 284.74 | 3.43 | 3.43 |
| 383.24 | 1.92 | 1.92 |
| 358.42 | 2.32 | 2.32 |
| 277.66 | 3.74 | 3.74 |
| 347.44 | 4.98 | 4.98 |
| 285.69 | 2.55 | 2.55 |
| 215.30 | 2.96 | 2.96 |
| 406.83 | 3.15 | 3.15 |
| 337.76 | 2.70 | 2.70 |
| 348.45 | 4.25 | 4.25 |
| 434.45 | 3.71 | 3.71 |
| 202.21 | 2.02 | 2.02 |
| 427.29 | 2.01 | 2.01 |
| 522.41 | 4.32 | 4.32 |
| 307.35 | 2.29 | 2.29 |
| 305.21 | 2.55 | 2.55 |
| 396.56 | 4.69 | 4.69 |
| 437.93 | 4.05 | 4.05 |
| 382.35 | 3.03 | 3.03 |
| 268.27 | 2.62 | 2.62 |
| 297.14 | 3.41 | 3.41 |
| 297.27 | 2.91 | 2.91 |
| 364.38 | 3.09 | 3.09 |
| 321.33 | 3.08 | 3.08 |
| 278.31 | 3.28 | 3.28 |
| 425.53 | 4.84 | 4.84 |
| 452.51 | 4.71 | 4.71 |
| 417.42 | 2.09 | 2.09 |
| 357.45 | 3.26 | 3.26 |
| 277.33 | 2.67 | 2.67 |
| 510.43 | 4.86 | 4.86 |
| 442.67 | 4.61 | 4.61 |
| 275.70 | 2.42 | 2.42 |
| 359.39 | 3.85 | 3.85 |
| 395.53 | 2.71 | 2.71 |
| 238.29 | 3.31 | 3.31 |
| 304.18 | 2.00 | 2.00 |
| 327.38 | 4.56 | 4.56 |
| 382.42 | 4.13 | 4.13 |
| 417.92 | 3.10 | 3.10 |
| 344.21 | 4.46 | 4.46 |
| 312.87 | 2.71 | 2.71 |
| 405.46 | 3.37 | 3.37 |
| 301.30 | 3.03 | 3.03 |
| 288.80 | 4.59 | 4.59 |
| 501.77 | 4.42 | 4.42 |
| 356.81 | 3.72 | 3.72 |
| 291.78 | 3.62 | 3.62 |
| 467.32 | 3.76 | 3.76 |
| 279.30 | 3.73 | 3.73 |
| 223.66 | 2.60 | 2.60 |
| 507.25 | 4.68 | 4.68 |
| 325.37 | 3.51 | 3.51 |
| 267.28 | 3.04 | 3.04 |
| 244.16 | 0.26 | 0.26 |
| 548.68 | 5.01 | 5.01 |
| 232.24 | 1.41 | 1.41 |
| 496.08 | 5.42 | 5.42 |
| 385.52 | 4.53 | 4.53 |
| 333.39 | 2.54 | 2.54 |
| 346.49 | 1.96 | 1.96 |
| 594.15 | 5.70 | 5.70 |
| 496.59 | 1.54 | 1.54 |
| 227.27 | 3.03 | 3.03 |
| 459.36 | 2.67 | 2.67 |
| 269.22 | 3.87 | 3.87 |
| 447.37 | 3.04 | 3.04 |
| 281.78 | 2.32 | 2.32 |
| 529.62 | 2.41 | 2.41 |
| 279.39 | 2.84 | 2.84 |
| 427.55 | 5.04 | 5.04 |
| 333.26 | 1.66 | 1.66 |
| 364.20 | 2.07 | 2.07 |
| 271.32 | 2.86 | 2.86 |
| 349.76 | 3.82 | 3.82 |
| 460.56 | 2.02 | 2.02 |
| 401.55 | 2.93 | 2.93 |
| 302.76 | 2.71 | 2.71 |
| 251.29 | 2.51 | 2.51 |
| 402.50 | 3.21 | 3.21 |
| 237.28 | 1.64 | 1.64 |
| 292.68 | 2.79 | 2.79 |
| 295.39 | 2.32 | 2.32 |
| 329.83 | 3.50 | 3.50 |
| 336.40 | 2.90 | 2.90 |
| 364.41 | 2.16 | 2.16 |
| 302.34 | 3.76 | 3.76 |
| 335.19 | 4.72 | 4.72 |
| 339.42 | 3.16 | 3.16 |
| 371.38 | 2.08 | 2.08 |
| 421.91 | 2.98 | 2.98 |
| 324.30 | 2.78 | 2.78 |
| 320.82 | 2.84 | 2.84 |
| 458.43 | 1.68 | 1.68 |
| 286.29 | 2.55 | 2.55 |
| 309.42 | 2.30 | 2.30 |
| 346.82 | 2.93 | 2.93 |
| 297.36 | 2.15 | 2.15 |
| 307.35 | 4.34 | 4.34 |