ID: ALA1794578
Type: Functional
Description: PUBCHEM_BIOASSAY: SAR Analysis of small molecule inhibitors of Sentrin-specific protease 7 (SENP7) using a Luminescent assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID434973, AID434986]
Bioactivity
Activity Types for Assay ALA1794578
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
292.34 | 2.71 | 2.71 |
286.72 | 4.11 | 4.11 |
308.34 | 3.05 | 3.05 |
278.31 | 3.30 | 3.30 |
278.72 | 3.80 | 3.80 |
210.25 | 1.88 | 1.88 |
222.25 | 2.97 | 2.97 |
310.40 | 4.76 | 4.76 |
298.73 | 4.27 | 4.27 |
277.23 | 2.95 | 2.95 |
280.33 | 4.02 | 4.02 |
321.34 | 3.57 | 3.57 |
256.23 | 3.15 | 3.15 |
249.27 | 3.30 | 3.30 |
333.44 | 2.74 | 2.74 |
397.44 | 2.34 | 2.34 |
351.38 | 4.67 | 4.67 |
273.32 | 2.66 | 2.66 |
350.42 | 4.43 | 4.43 |
278.35 | 4.15 | 4.15 |
280.28 | 3.32 | 3.32 |
261.32 | 3.43 | 3.43 |
445.34 | 4.74 | 4.74 |
272.30 | 4.11 | 4.11 |
490.99 | 4.34 | 4.34 |
320.35 | 3.31 | 3.31 |
320.14 | 3.43 | 3.43 |
296.39 | 4.08 | 4.08 |
284.27 | 1.77 | 1.77 |
414.53 | 5.00 | 5.00 |
398.37 | 3.41 | 3.41 |
366.47 | 2.74 | 2.74 |
408.55 | 3.53 | 3.53 |
307.35 | 3.68 | 3.68 |
463.36 | 3.82 | 3.82 |
278.27 | 0.68 | 0.68 |
399.29 | 4.39 | 4.39 |
507.64 | 4.41 | 4.41 |
354.41 | 3.32 | 3.32 |
316.40 | 4.03 | 4.03 |
364.43 | 4.58 | 4.58 |
322.32 | 2.78 | 2.78 |
264.32 | 3.76 | 3.76 |
459.37 | 5.13 | 5.13 |
268.34 | 4.28 | 4.28 |
321.35 | 4.66 | 4.66 |
253.33 | 3.95 | 3.95 |
289.72 | 3.63 | 3.63 |
282.27 | 3.75 | 3.75 |
408.94 | 4.89 | 4.89 |
252.73 | 3.30 | 3.30 |
315.41 | 4.18 | 4.18 |
307.35 | 4.11 | 4.11 |
308.82 | 4.57 | 4.57 |
294.31 | 3.62 | 3.62 |
294.79 | 4.26 | 4.26 |
340.43 | 5.02 | 5.02 |
432.27 | 4.26 | 4.26 |
330.84 | 4.73 | 4.73 |
416.30 | 5.44 | 5.44 |
315.41 | 4.18 | 4.18 |
299.28 | 2.45 | 2.45 |
295.34 | 3.41 | 3.41 |
292.75 | 4.10 | 4.10 |
300.75 | 4.50 | 4.50 |
436.47 | 5.34 | 5.34 |
423.52 | 5.08 | 5.08 |
465.54 | 5.29 | 5.29 |
397.43 | 3.08 | 3.08 |
352.44 | 2.83 | 2.83 |
394.29 | 4.70 | 4.70 |
264.28 | 3.61 | 3.61 |
342.83 | 5.52 | 5.52 |
336.37 | 3.19 | 3.19 |
401.92 | 5.55 | 5.55 |
368.41 | 2.76 | 2.76 |
302.26 | 4.32 | 4.32 |
478.04 | 5.18 | 5.18 |
346.80 | 3.73 | 3.73 |
344.87 | 5.60 | 5.60 |
261.33 | 3.01 | 3.01 |
348.79 | 5.40 | 5.40 |
265.27 | 3.83 | 3.83 |
445.57 | 4.12 | 4.12 |
313.38 | 3.02 | 3.02 |
356.76 | 5.22 | 5.22 |
429.95 | 5.65 | 5.65 |
260.34 | 3.61 | 3.61 |
392.55 | 4.68 | 4.68 |
316.45 | 4.95 | 4.95 |
294.81 | 4.47 | 4.47 |
350.90 | 5.61 | 5.61 |
316.74 | 3.98 | 3.98 |
279.30 | 3.31 | 3.31 |
290.37 | 4.86 | 4.86 |
337.81 | 5.17 | 5.17 |
368.39 | 3.23 | 3.23 |
291.76 | 3.54 | 3.54 |
449.97 | 5.06 | 5.06 |
387.41 | 4.97 | 4.97 |
313.43 | 4.23 | 4.23 |
266.27 | 4.05 | 4.05 |
339.44 | 5.44 | 5.44 |
308.29 | 0.69 | 0.69 |
307.35 | 4.11 | 4.11 |
336.44 | 3.12 | 3.12 |
368.44 | 2.53 | 2.53 |
278.31 | 3.92 | 3.92 |
342.38 | 3.33 | 3.33 |
291.29 | 3.92 | 3.92 |
720.46 | 8.45 | 8.45 |
363.43 | 5.61 | 5.61 |
303.29 | 4.63 | 4.63 |
249.32 | 3.92 | 3.92 |
274.37 | 3.92 | 3.92 |
368.35 | 3.08 | 3.08 |
366.51 | 6.11 | 6.11 |
385.82 | 5.32 | 5.32 |
342.78 | 4.58 | 4.58 |
359.86 | 5.79 | 5.79 |
238.25 | 3.11 | 3.11 |
330.84 | 5.36 | 5.36 |
327.18 | 4.67 | 4.67 |
456.35 | 3.77 | 3.77 |
411.46 | 5.10 | 5.10 |
297.75 | 4.14 | 4.14 |
383.90 | 4.36 | 4.36 |
242.23 | 2.06 | 2.06 |
294.79 | 4.26 | 4.26 |
429.35 | 3.83 | 3.83 |
316.47 | 5.16 | 5.16 |
426.32 | 3.76 | 3.76 |
393.41 | 6.15 | 6.15 |
392.17 | 4.65 | 4.65 |
260.34 | 3.61 | 3.61 |
413.48 | 4.04 | 4.04 |
314.77 | 4.89 | 4.89 |
330.48 | 5.26 | 5.26 |
280.30 | 4.35 | 4.35 |
308.82 | 4.57 | 4.57 |
269.74 | 4.27 | 4.27 |
252.27 | 3.45 | 3.45 |
308.36 | 4.60 | 4.60 |
408.55 | 3.36 | 3.36 |
336.35 | 3.93 | 3.93 |
209.27 | 1.28 | 1.28 |
342.81 | 5.26 | 5.26 |
369.42 | 4.83 | 4.83 |
421.88 | 5.53 | 5.53 |
466.52 | 3.48 | 3.48 |
330.31 | 5.32 | 5.32 |
317.44 | 4.35 | 4.35 |
343.41 | 5.27 | 5.27 |
437.97 | 4.54 | 4.54 |
330.48 | 5.26 | 5.26 |
536.51 | 5.45 | 5.45 |
425.49 | 5.49 | 5.49 |
394.38 | 4.00 | 4.00 |
471.65 | 5.34 | 5.34 |
253.28 | 3.75 | 3.75 |
329.23 | 4.92 | 4.92 |
294.79 | 4.26 | 4.26 |
374.18 | 4.51 | 4.51 |
395.35 | 5.72 | 5.72 |
310.38 | 4.33 | 4.33 |
335.41 | 4.46 | 4.46 |
402.28 | 3.56 | 3.56 |
314.77 | 4.74 | 4.74 |
249.32 | 3.92 | 3.92 |
325.42 | 5.14 | 5.14 |
487.58 | 3.75 | 3.75 |
262.31 | 4.22 | 4.22 |
457.45 | 1.23 | 1.23 |
295.78 | 3.66 | 3.66 |
265.32 | 3.62 | 3.62 |
437.33 | 2.90 | 2.90 |
379.28 | 5.25 | 5.25 |
443.50 | 5.09 | 5.09 |
355.44 | 5.14 | 5.14 |
382.83 | 3.75 | 3.75 |
402.28 | 5.83 | 5.83 |
412.49 | 1.23 | 1.23 |
422.34 | 5.48 | 5.48 |
284.37 | 2.05 | 2.05 |
333.34 | 4.46 | 4.46 |
384.44 | 1.30 | 1.30 |
443.53 | 5.54 | 5.54 |
364.47 | 5.95 | 5.95 |
375.35 | 2.88 | 2.88 |
294.79 | 4.26 | 4.26 |
308.82 | 4.57 | 4.57 |
391.25 | 4.08 | 4.08 |
314.41 | 4.43 | 4.43 |
328.78 | 4.95 | 4.95 |
308.34 | 3.92 | 3.92 |
280.29 | 3.52 | 3.52 |
444.00 | 3.62 | 3.62 |
476.96 | 4.03 | 4.03 |
439.46 | 6.13 | 6.13 |
358.89 | 5.99 | 5.99 |
359.47 | 4.57 | 4.57 |
425.33 | 4.10 | 4.10 |
300.36 | 4.25 | 4.25 |
431.34 | 3.59 | 3.59 |
318.37 | 2.61 | 2.61 |
423.52 | 4.66 | 4.66 |
299.33 | 4.46 | 4.46 |
356.22 | 4.86 | 4.86 |
282.30 | 3.20 | 3.20 |
334.27 | 5.06 | 5.06 |
407.84 | 2.76 | 2.76 |
328.80 | 5.13 | 5.13 |
312.76 | 4.57 | 4.57 |
206.18 | 2.08 | 2.08 |
300.38 | 4.48 | 4.48 |
276.34 | 4.47 | 4.47 |
459.57 | 4.81 | 4.81 |
474.55 | 5.64 | 5.64 |
440.31 | 3.56 | 3.56 |
235.29 | 3.61 | 3.61 |
262.31 | 4.22 | 4.22 |
441.55 | 6.82 | 6.82 |
403.51 | 4.54 | 4.54 |
266.27 | 4.05 | 4.05 |
352.44 | 2.83 | 2.83 |
358.40 | 3.41 | 3.41 |
325.80 | 5.14 | 5.14 |
333.39 | 3.74 | 3.74 |
436.27 | 5.51 | 5.51 |
273.30 | 3.78 | 3.78 |
382.91 | 3.61 | 3.61 |
278.33 | 3.75 | 3.75 |
362.48 | 3.79 | 3.79 |
316.45 | 4.95 | 4.95 |
446.99 | 5.34 | 5.34 |
279.25 | 0.08 | 0.08 |
288.76 | 4.62 | 4.62 |
254.25 | 2.81 | 2.81 |
298.73 | 4.27 | 4.27 |
352.26 | 5.20 | 5.20 |
284.27 | 4.19 | 4.19 |
400.44 | 1.01 | 1.01 |
388.25 | 3.17 | 3.17 |
259.24 | 2.81 | 2.81 |
451.98 | 4.67 | 4.67 |
386.89 | 3.48 | 3.48 |
303.81 | 4.58 | 4.58 |
291.29 | 3.92 | 3.92 |
370.25 | 5.25 | 5.25 |
324.41 | 3.96 | 3.96 |
284.27 | 4.19 | 4.19 |
266.28 | 4.05 | 4.05 |
274.33 | 1.65 | 1.65 |
308.34 | 3.92 | 3.92 |
294.33 | 4.61 | 4.61 |
332.36 | 3.21 | 3.21 |
353.45 | 4.53 | 4.53 |
452.51 | 3.91 | 3.91 |
299.40 | 3.74 | 3.74 |
475.98 | 2.90 | 2.90 |
318.71 | 4.84 | 4.84 |
459.50 | 4.94 | 4.94 |
581.16 | 3.84 | 3.84 |
311.27 | 3.95 | 3.95 |
308.30 | 3.40 | 3.40 |
353.38 | 2.89 | 2.89 |