Assay Report Card

Basic Information

ID: ALA1798117

Type: Binding

Description: Inhibition of endothelin A receptor in New Zealand white rabbit aortic rings assessed as inhibition of endothelin-1-induced vascular contraction at 10'-6 M

Organism: Oryctolagus cuniculus

Strain: New Zealand white

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
551.634.204.20
378.433.523.52
450.494.084.08
464.524.474.47
478.554.864.86
478.554.724.72
532.624.634.63
468.554.564.56
420.514.344.34
434.544.734.73
420.473.473.47
434.493.863.86
448.524.264.26
462.554.654.65
476.575.045.04
504.635.825.82
476.574.894.89
462.554.504.50
462.554.504.50
449.513.613.61
478.503.323.32
492.533.713.71
482.544.774.77
512.564.784.78
496.565.085.08
483.524.164.16
483.524.164.16
496.564.704.70
510.595.095.09
436.463.693.69
378.432.902.90
373.413.443.44
438.535.155.15
360.413.383.38
392.463.563.56
406.483.953.95
418.494.114.11
468.555.135.13