Basic Information
ID: ALA1799011
Type: Functional
Description: Antagonist activity at TLR7 expressed in HEK293 cells co-transfected with NF-kappaB/sAP gene assessed as inhibition of 1 ug/ml of gardiquimod-induced NF-kappaB activation by reporter gene assay
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1799011
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 346.43 | 3.75 | 3.75 |
| 264.33 | 2.33 | 2.33 |
| 240.31 | 2.23 | 2.23 |
| 283.33 | 3.88 | 3.88 |
| 259.31 | 3.79 | 3.79 |
| 371.48 | 5.69 | 5.69 |
| 289.38 | 4.27 | 4.27 |
| 265.36 | 4.17 | 4.17 |
| 367.54 | 5.65 | 5.65 |
| 415.58 | 6.93 | 6.93 |
| 333.48 | 5.51 | 5.51 |
| 309.46 | 5.41 | 5.41 |
| 486.60 | 6.26 | 6.26 |