Basic Information
ID: ALA1799012
Type: Functional
Description: Antagonist activity at TLR8 expressed in HEK293 cells co-transfected with NF-kappaB/sAP gene assessed as inhibition of CL075-induced NF-kappaB activation by reporter gene assay
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1799012
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 298.39 | 2.46 | 2.46 |
| 314.39 | 1.70 | 1.70 |
| 417.51 | 3.72 | 3.72 |
| 346.43 | 3.75 | 3.75 |
| 264.33 | 2.33 | 2.33 |
| 240.31 | 2.23 | 2.23 |
| 317.39 | 4.02 | 4.02 |
| 303.37 | 3.63 | 3.63 |
| 283.33 | 3.88 | 3.88 |
| 259.31 | 3.79 | 3.79 |
| 323.44 | 4.40 | 4.40 |
| 371.48 | 5.69 | 5.69 |
| 309.41 | 4.01 | 4.01 |
| 289.38 | 4.27 | 4.27 |
| 265.36 | 4.17 | 4.17 |
| 367.54 | 5.65 | 5.65 |
| 415.58 | 6.93 | 6.93 |
| 353.51 | 5.26 | 5.26 |
| 333.48 | 5.51 | 5.51 |
| 309.46 | 5.41 | 5.41 |
| 486.60 | 6.26 | 6.26 |