Basic Information
ID: ALA1799013
Type: Functional
Description: Antagonist activity at TLR7 expressed in HEK293 cells co-transfected with NF-kappaB/sAP gene assessed as inhibition of gardiquimod-induced NF-kappaB activation at 250 uM by reporter gene assay
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1799013
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 314.39 | 1.70 | 1.70 |
| 417.51 | 3.72 | 3.72 |
| 284.36 | 2.08 | 2.08 |
| 317.39 | 4.02 | 4.02 |
| 365.44 | 5.31 | 5.31 |
| 303.37 | 3.63 | 3.63 |
| 323.44 | 4.40 | 4.40 |
| 309.41 | 4.01 | 4.01 |
| 353.51 | 5.26 | 5.26 |