Basic Information
ID: ALA1799368
Type: Binding
Description: Inhibition of recombinant perforin mediated lysis of human Jurkat cells pre-incubated for 30 mins with perforin followed by incubation with Jurkat cells at 37 degC for 4 hrs in presence of 0.1% BSA by [51Cr] release assay
Cell type: Jurkat
Activity Charts
Bioactivity
Activity Types for Assay ALA1799368
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 325.41 | 4.94 | 4.94 |
| 366.38 | 2.84 | 2.84 |
| 440.46 | 2.36 | 2.36 |
| 318.34 | 2.49 | 2.49 |
| 382.38 | 2.34 | 2.34 |
| 396.41 | 2.60 | 2.60 |
| 410.44 | 2.95 | 2.95 |
| 410.44 | 2.99 | 2.99 |
| 424.46 | 3.39 | 3.39 |
| 424.46 | 3.38 | 3.38 |
| 369.38 | 2.85 | 2.85 |
| 394.44 | 3.16 | 3.16 |
| 408.47 | 3.50 | 3.50 |
| 426.44 | 1.97 | 1.97 |
| 440.46 | 2.36 | 2.36 |
| 456.46 | 1.33 | 1.33 |
| 487.52 | 3.61 | 3.61 |
| 352.36 | 2.58 | 2.58 |
| 380.41 | 3.18 | 3.18 |
| 380.41 | 3.23 | 3.23 |
| 396.41 | 2.20 | 2.20 |
| 410.44 | 2.59 | 2.59 |
| 410.44 | 2.59 | 2.59 |
| 426.44 | 1.56 | 1.56 |
| 423.48 | 2.77 | 2.77 |
| 463.55 | 3.70 | 3.70 |
| 465.52 | 2.54 | 2.54 |
| 457.50 | 3.85 | 3.85 |
| 396.41 | 2.65 | 2.65 |
| 416.83 | 3.00 | 3.00 |
| 412.41 | 2.35 | 2.35 |
| 410.44 | 2.96 | 2.96 |
| 410.44 | 2.96 | 2.96 |
| 332.36 | 2.80 | 2.80 |
| 352.78 | 3.14 | 3.14 |
| 348.36 | 2.50 | 2.50 |
| 346.39 | 3.11 | 3.11 |
| 346.39 | 3.11 | 3.11 |