Basic Information
ID: ALA1799370
Type: Binding
Description: Inhibition of perforin released from human KHYG-1 NK cells assessed as inhibition of perforin mediated lysis of human K562 cells at 20 uM in presence of 10% mouse serum by [51Cr] release assay
Organism: Homo sapiens
Cell type: K562
Activity Charts
Bioactivity
Activity Types for Assay ALA1799370
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 325.41 | 4.94 | 4.94 |
| 366.38 | 2.84 | 2.84 |
| 382.38 | 2.34 | 2.34 |
| 396.41 | 2.60 | 2.60 |
| 410.44 | 2.95 | 2.95 |
| 410.44 | 2.99 | 2.99 |
| 424.46 | 3.39 | 3.39 |
| 424.46 | 3.38 | 3.38 |
| 369.38 | 2.85 | 2.85 |
| 408.47 | 3.50 | 3.50 |
| 426.44 | 1.97 | 1.97 |
| 352.36 | 2.58 | 2.58 |
| 380.41 | 3.23 | 3.23 |
| 396.41 | 2.20 | 2.20 |
| 410.44 | 2.59 | 2.59 |
| 410.44 | 2.59 | 2.59 |
| 426.44 | 1.56 | 1.56 |
| 465.52 | 2.54 | 2.54 |
| 457.50 | 3.85 | 3.85 |
| 396.41 | 2.65 | 2.65 |
| 410.44 | 2.96 | 2.96 |
| 410.44 | 2.96 | 2.96 |