Assay Report Card

Basic Information

ID: ALA1803436

Type: Functional

Description: Agonist activity at human SXR transfected in human HepG2 cells coexpressing GAL4 assessed as activation of receptor-mediated CYP3A4 gene transcription at 1 X 10'-6 M after 48 hrs by luciferase reporter gene assay

Organism: Homo sapiens

Cell type: HepG2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
822.954.344.34
324.424.444.44
392.546.166.16
460.667.897.89
376.547.197.19
444.668.928.92
384.526.696.69
452.648.418.41
240.303.743.74